Urosepsis Flashcards

0
Q

Risk factors for UTIs?

A

Incontinence, prior UTIs, neurologic impairment, anti-cholinergics

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1
Q

Most common infections in patients older than 65 years?

A

Pneumonia >UTIs

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2
Q

In symptomatic patients how much bacteria is typically found in the urine?

A

10^5 colony forming units from a clean catch specimen

10^2 from catheterization

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3
Q

Leukocyte esterase versus nitrites?

A

Pyuria versus bacteriuria

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4
Q

Clinical syndromes of UTIs?

A

Acute uncomplicated cystitis – lower tract infection

Acute uncomplicated pyelonephritis – upper tract infection

Complicated UTI – associated with urinary catheter or functional abnormalities

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5
Q

Symptoms of cystitis Versus pyelonephritis?

A

Dysuria, frequency, urgency, hematuria versus Fevers, chills, and nausea, with or without symptoms of cystitis

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6
Q

Suspected UTI, begin treatment when?

A

Immediately (before results of cultures)

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7
Q

Treatment for uncomplicated UTIs? In patients presenting with clinical picture of sepsis?

A

Fluoroquinolones (ciprofloxacin and gatifloxacin)

Gentamicin, imipenem, Bactrim

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8
Q

Hypovolemic shock results with how much loss of fluid?

A

20 to 40% blood volume

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9
Q

Treatment of cardiogenic shock?

A
  1. Maintain blood pressure dopamine or norepinephrine
  2. Relieve pulmonary edema with diuretics
  3. Reduce cardiac afterload with intrathoracic balloon pump
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10
Q

Distributive shock?

A

Increase in cardiac output with inability to maintain vascular resistance (inappropriately vasodilation)

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11
Q

Phases of distributive shock?

A
  1. Initially, extremities are warm and well perfused

2. Cardiac output falls causing intense vasoconstriction (cold things)

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12
Q

Causes of distributive shock?

A
  1. Septic shock

2. Neurogenic shock from spinal cord injury or adrenal crisis

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13
Q

Treatment of Distributive shock?

A
  1. Isotonic volume repletion
  2. Vasopressors support (dopamine)
  3. Mechanical ventilation
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14
Q

Mortality from all types of shock?

A

50%

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15
Q

Only type of patient to benefit from asymptomatic bacteriuria? Why?

A

Pregnant patients. Prevents upper tract infection, preterm delivery, fetal loss

16
Q

Dose regimens for UTIs?

A

Acute uncomplicated cystitis – Single-dose ciprofloxacin or 3 Day dose bactrim useful

Pyelonephritis – 14 day course of IV then oral gatifloxacin

17
Q

Ways to increase BP in shock?

A
  1. Volume resuscitation
  2. Dopamine/norepinephrine
  3. Corticosteroids