Rhabdomyolysis

Question 0

Inhaling cocaine can cause?

Answer 0

Pneumonitis or ARDS

Question 1

Treatment for suspected rhabdomyolysis?

Answer 1

1. Aggressive IV hydration with normal saline

2. Chemical restraint of patient to prevent further damage

Question 2

Treatment of cocaine induced cardiac ischemia?

Answer 2

Aspirin, benzodiazepines, and nitrates

Avoid beta blockers because they may exacerbate alpha-mediated vasoconstriction

Question 3

Cocaine can cause rhabdomyolysis how? PCP?

Answer 3

Direct my toxicity or vasoconstrictive ischemia

Muscle breakdown from overexertion

Question 4

Drugs that cause of rhabdomyolysis?

Answer 4

Drugs (cocaine, amphetamine, LSD, heroin, PCP, alcohol)

Medications (diuretics, narcotics, theophylline, steroids, benzodiazepines, tricyclics)

Question 5

Other causes of rhabdomyolysis?

Answer 5

Trauma
High temperatures
Heatstroke
Strenuous exercise
Seizures

Question 6

Mechanisms of the effects of muscle breakdown on kidney?

Answer 6

1. Myoglobin can precipitate kidney tubules causing the acute renal failure
2. Damage muscle cancer sequester fluid leading to intravascular depletion and hypovolemia
3. Free iron toxic to renal tubules

Question 7

Key finding in urine analysis of rhabdomyolysis?

Answer 7

Urine dipstick shows blood but no red blood cells seen on microscopy Indicates (hemoglobinuria or myoglobinuria)

Question 8

Left untreated, early complications of rhabdomyolysis?

Answer 8

Hyperkalemia, hypocalcemia, arrhythmias, cardiac arrest

Question 9

Did not give patients with rhabdomyolysis these drugs, as they may worsen the situation?

Answer 9

Diuretics