Peripheral Vascular Dz Flashcards
Most important risk factors for peripheral artery disease? Other risk factors?
Cigarette smoking and diabetes mellitus
Hypertension, dyslipidemia, elevated homocysteine
Ankle brachial index? Determined by?
Ratio of ankle brachial systolic blood-pressure. determined using Doppler ultrasound
Peripheral artery disease confers the same risk of cardiovascular death as?
Prior myocardial infarction or stroke
Patient with aortoiliac disease may complain of exertional pain where?
Thighs or butt
Rest pain in peripheral arterial disease indicates?
Severe occlusion
Bruits on physical exam indicate?
Accelerated blood flow velocity and turbulence at the sites of stenosis
In a patient with a peripheral artery disease, elevation of the feet will induce? If feet are then placed in dependent position?
Pallor in the soles. Redness as a result of reactive hyperemia
Chronic arterial insufficiency may cause what findings? In severe cases?
Hair loss on legs and feet, thickened toenails, atrophic shiny skin
Ulcers or gangrene
Normal ankle brachial index? In patients with claudication? In patients with critical leg ischemia?
1+
.41 - .90
Less than .40
Mortality rate in patients with symptomatic peripheral artery disease
50% in 10 years
Intervention that reduces the risk of fatal or nonfatal MIs by as much as 50%?
Smoking cessation
Drug approved for the treatment of claudication? Mechanism of action?
Cilostazol. Phosphodiesterase inhibitor with vasodilatory and antiplatelet properties
Treatment of PAD includes?
- Treat cardiovascular risk factors (smoking cessation, hyperlipidemia, hypertension, aspirin, ACE inhibitor)
- Assess severity of claudication with treadmill test or maximal walking distance
- Angioplasty or bypass grafting
Who should be evaluated for revascularization?
patients with ankle brachial index less than .4, severe claudication, rest pain, or nonhealing ulcers should be evaluated for?
An ideal candidate for revascularization?
Ideal candidates have discrete stenosis of large vessels (Diffuse or small-vessel disease patients respond poorly)