Urology Meds and treatments

Question 1

Alpha-1 adrenergic antagonist used in treatment of BPH

Answer 1

Terazosin
Doxazosin
Tamulosin - least effect on BP, low risk hypotension
Alfuzosin
Silodosin 

Relaxes smooth muscle in the bladder neck, Prostate capsule, prostatic urethra

S/E: postural hypotension

Question 2

5 alpha reductase inhibitors used to treat BPH

Answer 2

finasteride
dutasteride

Inhibits the conversion of testosterone to dihydrotestosterone
Decreases the size of the prostate
Decreases PSA

S/E: decreased libid, ED

Question 3

Phosphodiesterase-5 inhibitor used in the treatment of BPH

Answer 3

tadalafil

Improves urinary symptoms

S/E: potentiates hypotensive effects of Alpha blockers

Question 4

Anticholinergics using the treatment of BPH

Answer 4

Oxybutynin
tolterodine
darifenacin

Improve urinary urgency and frequency

S/E: dry mouth, urinary retention, constipation