Endo quick associations Flashcards

1
Q

DM drug that decreases the absorption of starch and disaccharides

A

Acarbose

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2
Q

DM drug that stimulates insulin release by inhibiting potassium ATP channel

A

sulfonylurease

meglitinides

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3
Q

DM drug that decreases hepatic gluconeogenesis

A

metformin

TZDs

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4
Q

DM drug mimics the action of GLP-1: lower glucagon, increased insulin, delays gastric emptying

A

GLP1 receptor agonists

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5
Q

DM drug that inhibits DPP-4 -> lower glucagon, increased insulin, delays gastric emptying

A

DPP4 inhibitors

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6
Q

DM drug that increases urinary elimination of sugar

A

SGLT2 inhibitors

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7
Q

Lactic acidosis is a rare But worrisome side effect

A

Metformin

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8
Q

Most common side effect is hypoglycemia

A

sulfonylurease

meglitinides

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9
Q

Oldest and cheapest to the oral non-insulin agents

A

sulfonylureas

metformin

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10
Q

First line for type II diabetes

A

metformin

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11
Q

Non-insulin drug not safe in setting of severe CHF

A

pioglitazone
TZDs
SGLT2

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12
Q

Non-insulin agent that should not be used in patients with renal dysfunction

A

SGLT2 inhibitors

caution - metformin

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13
Q

Non-insulin agents that are acceptable choices in patients with mild to moderate renal disease

A

TZDs
DPP4-inhibitors
Metformin

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14
Q

Non-insulin agents that increases risk for UTI and yeast infections

A

SGLT2-inhibitor

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15
Q
Patient presents with hypoglycemia labs reveal:
Elevated insulin level
Low C-peptide
Low pro-insulin
Sulfonylurea screen - negative
A

Excess Exogenous insulin

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16
Q
Patient presents with hypoglycemia labs reveal:
Elevated insulin level
Elevated C-peptide
Elevated pro insulin
Sulfonylurea screen: positive
A

Adverse effect of sulfonylurea use

17
Q
Patient presents with hypoglycemia with fasting, labs reveal:
Elevated insulin level
Elevated C-peptide
Elevated pro insulin
Sulfonylurea screen - negative
A

Insulinoma - usually in pancreas

CT/MRI to localize
Tx: diazoxide and octreotide

18
Q

Painless goiter + hypothyroid

Increased risk of B cell lymphoma of thyroid

A

Hashimoto thyroiditis

19
Q

Painful goiter + fever

Hyper or hypothyroidism

A

subacute thyroiditis

20
Q

Fixed, hard, rock-like, painless thyroid in young patient

euthyroid or hypothyroid

A

Riedel’s thyroiditis

21
Q

RET oncogene

A

MENII syndromes