urinary systems and components 1 Flashcards

1
Q

what are the components are the urinary system?

A

2 kidneys, 2 ureters, a urinary bladder and urethra.

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2
Q

what is nephrology?

A

scientific study of anatomy, physiology and pathology of kidney

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3
Q

what is urology ?

A

a branch of medicine dealing with male and female urinary systems and male reproductive system.

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4
Q

what are the 8 functions of kidney?

A

1) regulation of blood ion composition (Na +, K+, Ca2+, [HPO4]2-.
2) maintenance of blood osmolarity.( regulating loss of water and solutes in urine, maintains 290mOsm/litre)
3) regulation of blood volume ( by conserving or eliminating water).
4) regulation of blood pressure.
5) regulation of blood pH
6) release of hormones (calcitriol and erythropoietin)
7) regulation of blood glucose level
8) secretion of waste & foreign substances.

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5
Q

How do kidneys regulate blood pressure ?

A
  • Adjusting blood volume (= adjusting blood pressure)
  • Renin secretion (increases vasoconstriction & blood volume = increased blood pressure)
  • adjusts renal resistance (increases renal resistance = increased blood pressure)
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6
Q

what waste and foreign substances does the kidneys secrete through urine?

A

-Ammonia and urea (from AA)
- bilirubin (from catabolism of Hb)
- creatinine (from breakdown of creatinine phosphate in muscles)
- uric acid (from catabolism of nucleic acids
- drugs and environmental toxins.

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7
Q

Where are the kidneys found in the body?

A

Paired above waist at concave side, all blood & lymphatic vessels, nerves and ureter enter/leave by the renal hilum.

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8
Q

what are the 3 layers of tissue surrounding the kidneys?

A

renal capsule, adipose capsule, renal fascia.

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9
Q

describe the renal cortex in the kidneys.

A

outer, smooth, reddish.

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10
Q

what are the portions that extend between the renal pyramids called?

A

renal columns.

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11
Q

Describe the renal medulla in the kidneys.

A

Inner, reddish/brown. consists of 8-18 cone shaped renal pyramids.

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12
Q

where are the renal papilla found ?

A

the part of the renal pyramid that points to the centre.

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13
Q

what is the renal parenchyma?

A

the functional part of the kidney. composed of renal cortex and renal pyramids

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14
Q

Describe nephrons in the kidneys.

A

Functional unit of the kidney, within parenchyma, 1 million microscopic units.

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15
Q

where is urine formed?

A

in the nephron.

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16
Q

Explain how urine travels.

A

Urine formed in nephron – papillary ducts – minor or major – renal pelvis – ureter – urinary bladder

17
Q

explain the renal corpuscle .

A

It filters the plasma,
- glomerulus , mass of capillary loops
- Bowmans capsule - glomerular capsule surrounds glomerulus.

18
Q

explain renal tubules

A

into which filtered fluid passes-
1 - proximal convoluted - attached to Bowman’s capsule.
2) loop of henle - descending, hairpin, ascending
3) distal convoluted tubule.

19
Q

do kidneys contain abundant supply of blood vessels?

A

yes, they remove waste from blood and regulate its volume and composition.

20
Q

what % of kidneys take up body mass?

A

Less than 0.5 %, but recieve 20-25% cardiac output via L & R renal arteries.

21
Q

What is an adults renal blood flow per minute?

A

1.2 litres per minute.

22
Q

explain the path of blood Flow through the kidneys.

A

Large arteries to small, small to large veins.

23
Q

Explain the composition of glomerular (bowmans) capsule.

A
  • Outer parietal layer wall of simple squamous epithelium.
  • inner visceral layer of specialised simple squamous epithelial cells = podocytes.
24
Q

what do podocytes (inner visceral cells) do?

A

podocytes - wrap around the glomerular capillaries.

25
Q

what 2 things make up the filtration membrane?

A

podocytes and fenestrated capillaries, it is 0.1 mm thick.

26
Q

what passes from blood to capsular space if molecule is less than 6nm? what stays in blood?

A

H2O, Glucose, Vitamins, AA, Small plasma proteins, urea, ammonia, ions.
Stays in blood - albumen 7.1nm, plasma proteins, platelets, rbc , wbc

27
Q

what does prominent brush border of microvilli in proximal convoluted tubule cells do?

A

increases surface area for reabsorption and secretion.

27
Q

Last portion of distal collecting duct has 2 different cells, what are they?

A

Mainly - principal cells(receptors for ADH and aldosterone)
fewer - intercalated cells ( apical microvilli and many mitochondria , play a role in haemostasis of blood pH.

Drain to large papillary ducts. lined by simple columnar epithelial cells.