Bone structure 19 Flashcards

1
Q

Describe and name types of long bones.

A

Longer rather than wide bones such as thigh, leg, arm, forearm, fingers & toes.

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2
Q

Describe and name types of short bones.

A

Almost cubed shaped bones such as most wrist and ankle bones.

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3
Q

Describe and name types of Flat bones.

A

Bones with a thin and extensive surface such as cranial bones, sternum, ribs and scapulae.

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4
Q

Describe and name types of irregular bones.

A

Bones that don’t fit in any other category such as vertebrae and some facial bones.

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5
Q

What are the four bone shapes?

A

Long, flat, short, irregular.

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6
Q

Extracellular matrix consists of what (including %)

A

25% water, 25% collagen fibres, 50% crystallised mineral salts called hydroxyapatite (hydrated calcium phosphate).

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7
Q

What do osteogenic cells develop into?

A

Osteoblasts.

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8
Q

Where are osteogenic cells found?

A

Periosteum.

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9
Q

Explain the functions of osteoblasts.

A

Secrete collagen fibres. Build matrix & become trapped in lacunae to become osteocytes.

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10
Q

Explain how osteoblasts become osteocytes.

A

osteoblasts become trapped in lacunae.

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11
Q

What is the function of osteocytes.

A

To maintain bone.

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12
Q

What are osteoclasts formed from?

A

Monocytes (white blood cell)

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13
Q

What is the function of osteoclasts?

A

Digest, breakdown bone matrix for normal bone turnover.

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14
Q

Describe The microscopic structure of bone.

A

Osteogenic cells (found in periosteum) develop into osteoblasts (secrete collagen fibres, forms matrix) and become osteocytes (by becoming trapped in lacunae). Osteocytes maintain bone tissue. White blood cells (monocytes) form osteoclasts (digest, breakdown bone matrix for normal bone turnover.

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15
Q

Compact bone structure takes up what % of bone in the body?

A

80%

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16
Q

Spongy/cancellous bone takes up what percentage of bone in the body?

A

20%

17
Q

what do ‘volkmanns (perforating) canals’ do?

A

Complete the communication pathway from the outside of the bone to its interior. These run into the compact bone at right angles to the shaft.

18
Q

what part of the bone uses osteons as units?

A

Compact bone structure.

19
Q

What part of the bone include both lacunae and canaliculae?

A

Both parts; compact bone structure & spongy/cancellous bone.

20
Q

What are the 6 functions of the bone.

A

support,
protection,
leverage - for motion,
mineral homeostasis e.g. calcium,
blood cell production - haemopoiesis in red bone marrow,
triglyceride (fat) storage- yellow bone marrow.

21
Q

Negative feedback loops control blood levels of what mineral during homeostasis?

A

Calcium (Ca2+)

22
Q

What 3 hormones are used during homeostasis to regulate calcium transport in the blood?

A

Parathyroid Hormone, Calcitriol, calcitonin.

23
Q

What does parathyroid hormone do?

A

Detect lowered calcium levels. Increases osteoclast activity & decreases loss in urine.

24
Q

What does hormone Calcitriol do?

A

Secreted from kidneys, increases absorption of calcium from the blood.

25
Q

What does hormone Calcitonin do?

A

Secreted from thyroid glands, opposes parathyroid hormone. Decreases osteoclast activity.

26
Q

In the macroscopic structure of a bone, what is the shaft known as?

A

Diaphysis.

27
Q

In the macroscopic structure of a bone, what is the terminal portion known as?

A

Epiphysis

28
Q

In the macroscopic structure of a bone, describe the metaphysis.

A

vascular region adjoining epiphyseal cartilage.

29
Q

In the macroscopic structure of a bone, what is the part situated at a joint known as?

A

Articular Cartilage.

30
Q

In the macroscopic structure of a bone, what is the fibrous membrane called?

A

Periosteum.

31
Q

In the macroscopic structure of a bone, what is the central hollow space called?

A

Medullary cavity.

32
Q

In the macroscopic structure of a bone, what is the membrane lining the inner cavity called?

A

Endosteum.

33
Q

draw an osteogenic cell.

A

Now draw an osteoblast, an osteocyte & an Osteoclast

34
Q

what does lacunae contain?

A

osteocytes.