Urinary Flashcards
Micturition/urination
Process of eliminating urine
How does urinary system stabilize blood pH
Controls loss of H+ and bicarbonate
Which ribs are the kidneys found near
11th and 12th
“Barely protected”
Function of renal lobule
Produce urine
When is the waste in the urinary tract called urine
When it reaches renal pelvis
After it passes minor calyx
Basic unit of a kidney
Nephron
Function of nephron
Produce urine
Cortical nephrons
Nephrons that have loop of henles mostly in the renal cortex
What is a juxtamedullary nephron
Nepohrons that have loops that extend mostly into renal pyramids
Where do nephrons start
Renal corpuscle
Function of glomerulus
Filters fluid and solutes from blood into capsule
Filtrate description
Protein and cell free solution
Renal corpuscle is for production of filtrate true/false
True
Proximal convoluted tubule function
For water & solute reabsorption
What substances are secreted into filtrate by tubule system
Ions, acids, drugs, & toxins
Where does tubule system release secretions into filtrate via hormones
Distal convoluted tubule
Most common nephrons in the kidneys
Cortical nephrons
Podocytes
Cells in glomerulus capsule that act as filtration slits
Filtration slits
Narrow gaps between adjacent pedocytes
Juxtaglomerular complex
Structure containing macula densa and juxtaglomerular cells
Macula densa
Cells that line distal convoluted tubule
Function of mesangual cells
Control diameter and rate of capillary blood flow,
Which tube is important solutes reabsorbed from filtrate
Proximal convoluted tubule
Organc nitrogenous waste products
Urea, creatinine, and uric acid, ammonia
What causes fatal dehydration from urinary system
Failure to concentrate filtrate in glomerular filtration
Where does active secretion occur in nephron
Distal convoluted tubule
Examples of substances that act as cotransporter
Glucose and sodium together
Renal threshold
Plasma concentration a specific compound or ion begins to appear in urine
Where do substances reabsorbed from filtrate go
Vasa recta or peritubular capillaries
How is small proteins reabsorbed at the distal convoluted tubule
Pinocytosis
Relationship of capillary hydrostatic pressure and glomerular hydrostatic pressure
Capillary hydrostatic pressure opposes glomerular hydrostatic pressure
-like BCOP
Glomerular filtration rate
The amount of filtrate kidneys produce each minute
What is creatinine clearance test
Examines how well the kidney is filtering the blood by estimating GFR
How is glomerular filtration rate maintained
Autoregulation, hormonal, and autonomic regulation
Countercurrent
One end is concentrating filtrate (medulla) another end is diluting it (cortex)
Benefits of countercurrent multiplication
- Efficiently reabsorbs solute and water
- Establish concentration gradient
Less ADH effect on water excretion
Increase loss of water
More ADH effect on water excretion
Less water loss
Diuresis
Elimination of urine
Pyuria
Excretion of excess of WBC
What action moves urine
Peristalsis
Where does peristalsis begin in urinary system
Renal pelvis
Capacity of bladder (average)
1L of urine
What holds bladder in place
Ligaments
Incontinence
Inability to control urination
Location of EPO and renin production
Juxtaglomerular complex/apparatus
How much filtrate is made in a day
180L or 48 gallons
How much filtrate is reabsorbed
98%
Filtrate components
Water, glucose, amino acids, nitrogenous waste.
Glomerular filtration rate
Rate at which you make filtrate
Anuria
Condition of not making enough urine
Average glomerular filtration rate
120-125mL per minute
2 ways to control filtration?
Control vasomotor regulation, and or mesangial cells
Symport
When 2 substances transport together through cells
Antiport
When 2 substances transport opposite of each other through a cell
Which tubes function in obligatory water reabsorption
PCT AND DCT
Which tubule functions in facultative water reabsorption
Collecting duct
What is the difference between facultative reabsorption and obligatory
Facultative is adjustable while obligatory is not
Transport maxium
The concept related to renal threshold
Countercurrent multiplier
The multiplying of the solute concentration of filtrate within the tubule
How is countercurrent multiplier’s effect diluted
Active transport, removing solutes
What is the osmolality of blood in glomerulus
300 mOsm
Function of vasa recta
Maintain salty gradient in medulla
What is the function of urea recycling? Like why do we do it
Last ditch effort to conserve water
Diuretics
Chemical that enhances urinary output