Test 1 Flashcards
What is tumor suppresor gene
Gene that limits cell proliferation
Carcinogenesis steps
Mutation, proto oncogene, oncogene expressed BAD protein, contagious cancer?
Karyotype
Individual complete set of chromosomes
2 advantages of karyotyping
Identify fetus gender and chromosomal anamolies
Stages of meiosis an mitosis
Prophase- metaphase- anaphase and telophase occurs twice in meiosis twice in mitosis
Features of phases for meiosis and mitosis
Chromosomes condense and the centrosomes begin to form early spindle
Difference of cell mitosis and meiosis
Mitosis produces 2 identical “daughter cells” while meiosis produces cells that are genetically unique and contain half as much dna
G0 phase description
The cell is not dividing or preparing to divide
What events occur during the s phase of the cell cycle
The dna replication and the duplication of the centriole
What is the purpose of DNA polymerase DNA helicase DNA ligase
DNA helicase unwinds the double helix seperatibg the 2 strands so they may be replicated by dna polymerase.dna ligates seals the gaps between the fragments
What are the steps of a protein that is produced or exported
Extracellular proteins are exported from the cell by the endoplasmic reticulum, proteins get folded into their correct shapes in the ER
Polyribosome
Group of ribosomes bound to an mRNA molecule. Translates mRNA instructions into polypeptides
Name all stop condons
UAG, UAA, UGA
Exon and intron
Exons are termed nucleic acid coding sequences, which are present in the mRNA. Introns are non coding sequences in the hnRNA which are removed by RNA splicing before translation
Rna polymerase definition and purpose
Multi unit enzyme that synthesizes rna molecules from a template of dna through a process called transcription
Kinetochore
Complex of proteins associated with the centromere of a chromosome during cell division, which the microtubules of the spindle attach
What is the start codon for translation
AUG Codon
Definition of gene
Is a dna sequence that codes for a specific protein
Dna replication is caused by
Semiconservative replication
Difference between sister and non sister chromatids
Sister chromatids are genetically identical and non sister share similar features but are not identical coming from the homologous chromosome pair
Define chromotin
Mixture of dna and proteins that form chromosomes
Define chromosome
Chromosomes are found in the nucleus and are made up of dna, tightly coiled around proteins easily observed in during cell division
Nitrogenous bases
Adenine, thymine, cytosine, guanine
How many rings in purine and pyrimidines
Purines have 2 rings pyrimidines have one ring
What are the purines and what are the pyrimidines
Adenine and cytosine are purines and thymine and uracil are pyrimindines
What holds nitrogenous bases together in double stranded DNA
Hydrogen bonds
How many hydrogen bonds bind A-T and G-C
2 A-T
3 G-C
Define nucleotide
Form basic structural unit of DNA
differences between active and passive transport
Active requires ATP, and moves things against concentration gradient. Passive is the opposite