upper gi microbiology Flashcards

1
Q

What is the most common bacterial cause of cavities?

A

Strep mutans - gram (+) bacteria

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2
Q

Describe the pathogens that cause periodontis

A
Red group pathogens
keystone
gram (-) anerobes
Treponema denticola
Tannerela forythia
porphyromomas gingivalis
Aggregatoribactor actinomycetemcomitans
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3
Q

How would you treat thrush?

A
  1. clotrimazole/nystatin mouthwash
  2. fluconazole
  3. IV Amphotericin
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4
Q

What are the symptoms of Ludwig’s angina?

A

breathing/swallowing problems
AMS
fever
neck pain/swelling/redness

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5
Q

Name as many virulence factors as you dare for Heliobacter pylori

A

catalase oxidase urease (+)
VacA - pore forming cytotoxin
CagA: T4SS injection of inflammatory stuff
adhesions
immuno-evasion with ROS and NOS
motility/chemotaxis - flagellate to low pH area

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6
Q

How does H. pylori cause disease?

A
  1. Elicit an immune response

2. Produce toxins

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7
Q

Describe the mechanism by which h. pylori causes disease

A

microbe attracts inflammatory cells
inflammatory cells can’t kill microbe
repeated inflammation causes damage

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8
Q

How can you distinguish gastritis from a gastric ulcer?

A

Gastric ulcers are worse on empty stomach, transient and cause night flares. Both have burning/aching, fullness of upper abdomen

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9
Q

How do you treat gastric ulcers, yo?

A

Triple therapy - 2 ab (clarithomycin + Amox) and PPI

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10
Q

Most common cancer caused by H. pylori

A

Gastric carcinoma - 65-80% of cases are caused by it

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11
Q

Describe why MALT B-cell lymphoma is a cancer that can be treated with antiobiotics

A

Antibiotics can arrest the long term inflammation that initially caused the cancer.

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12
Q

How would you treat serious peridontitis?

A

soft tissue/bone grafts

surgery

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