Small Intestine/ Colon Path Flashcards
necrosis of small and large bowels, 1st week of life in preemies
neonatal necrotizing entercolitis
describe drug induced enterocolitis
NSAIDs, chemo cause lesions of entire GI tract
lamina propria inflammation, increased plasma cells, intra-eptithelial lymphocyts and surface epthelial damage are all seen in this colitis
microscopic lymphocytic colitis
chronic bowel syndrome with no know cause, chronic replasping paing and and a normal colonscopy
irritiable bowel syndrome
sigmoid divericulitis is caused by this
elevated intraluminal pressure causing multiple inflamed diverticuli
malfunction of the puborectalis muscles is called this
solitary rectal ulcer syndrome
hamartomous solitary polyps of the rectum, no risk of malignancy
juvenile/retention polyps
syndrome with arbor like smooth muscle pattern, multiple polyps and mucocutanous hyper pigmentation
peutz-jeghers
non- malignant small polyps of the L colon/rectum are called this
hyperplastic polyps
these polyps are precursors to adenocarcinoma and occur anywhere in the colon.
adenomatous polyp
R colon precursor to adenocarcinoma without adenomatous epithelium
sessile serrated adenoma
What is Gardner’s syndrome?
FAP + desmoid tumors + osteoma + dental abnormalities+ thyroid tumors + epidermal cyst
what are the 2 types of Turcot syndrome?
FAP - medulloblastoma
HNPCC - glioblastoma multiformes
This syndrome of CRC cancer may spread as cancert to stomach/small bowel, liver or brain
Lynch Syndrome
What are risk factors for Colorectal adenocarcinoma?
diet low in fiber, high in carbs, smoking, obesity,
Loss of normal propulsive action of bowel
illeus
adhesions can cause these secondary problems
obstruction and int. herniation
malformed mucosal and submucosl vessels usually of the cecum
angiodysplasia
tests that can be done for celiac sprue
IgA, IgG, small bowel biopsy
Symptoms of this autosomal recessive mutation in microsomal tr-glyceride transporter protein include ftt, diarrhea, steatorrhea, and vit. def.
A-b lipoproteinemia
What is Whipple disease?
Systemic infection w/actinomycete tropheryma whippelii that causes lymph obstruction, abd. pain, diarrhea, arthritsis, fever etc.
This deficiency causes diarrhea, flatulence and distension
disaccharide def.
Describe symptoms of left sided small bowel adenomcarcinoma.
cramping, LLQ discomfort, change in bowel habits and bleeding
What is the most common GI tract neuroendocrine tumor?
small bowel
Describe neuroendocrine tumors of the colon
bulky R-sided high grade carcinoma
disorder in which laxative use turns the colonic mucosa brown
melanosis coli
Lymphomatosis is also called this
mantle cell lymphoma of large bowel
Busted open appendiceal mucinous tumors cause this disorder
pseudomyxoma peritonei
where do anal fissures usually occur?
90% posterior
anogential wart caused by HPV
Conydloma accuminatum
This neoplasia is pre-malignant squamous dysplasia of anal canal caused by HPV
Anal intraepithelial neoplasia
