Unit 8 Ab-Ag interaxn and aplplications

Question 1

Ag-Ab binding required what bonds

Answer 1

formation of non covalent bonds (weak attractive forces btwn Ab and Ag)

Question 2

name non-covalent forces

Answer 2

electrostatic, hydrogen, van der waals and hydrophobic forces

Question 3

specificity and affinity of Ab to Ag determined by (3)

Answer 3

good fit, max attractive forces, min repulsive forces, Ab affinity (intrinsic)

Question 4

what is Ab affinity

Answer 4

sum of attractive + repulsive forces

Question 5

eg of Ab affiity

Answer 5

strength of bond btwn monovalent Ab (Fab site) and monovalent Ag (single epitote)