first line of defense Flashcards
define innate immunity
inborn, natural, body components that block, destroy and or remove microbes
how does the mucociliary escalator protect the lungs
mucus traps unwanted particles and wave like motion of cilia expell microbes
eg of chemical barriers
stomach acid- low pH hostile environment for many enzymes
fn of lysozyme
breaks open bacterial cell wall causing lysis
where is lysozyme found
bllody fluids like tears, saliva and breastmilk
eg of genetic barrier
sickle cell anemia protects against malaria (RBC have abnormal hemoglobin- Plasmodium parasite cannot multiply)
how can some be naturally immune to HIV
lack coreceptors on CD4/T helper lymphocytes. requires binding to receptors in order to enter host cell
what are co receptors
kind of receptor for chemokine