UNIT 2: IMMUNIZATIONS & COMMUNICABLE DISEASES Flashcards
Vaccines stimulate the ______ to produce antibodies?
Immune system
Vaccines use the ____ antigens as disease but killed or weakened
Same
What happens after antibodies disappear after destorying antigens..
Memory cells are formed
Who decides what vaccines?
- Advisory committee on immunization practices (ACIP)
- Centers for disease control and prevention
- pink book
- Committee on infectious diseases
- American Academy of pediatrics
- Red book
Why vaccinate?
- Prevent infectious disease
- Society
- Decrease/eliminate certain infectious diseases
- heard immunity
- Potentaial for reemergence if we dont have enough of the population vaccinated
Other than vaccinations how else can we prevent infections?
- Immunization
- handwashing
- reduce cross-transmission of organisms
- follow isolation protcol
- infection control policies
- sneeze and cough etiquette
What do we need to know about active immunity?
gernalized
- Endogenous production of antibodies
- Takes weeks/months to develop
- Long-lasting
What are 2 ways to acquire active immunity?
- Survive infection
- Vaccination
Active immunity is actively formed by….
The persons own immune system in repsonce to an antigen
What should we know about passive immunity?
Generalized
- Antiboides given to a person
- Immediate protection
- Short-lived
- Most common- maternal/infant
True or false: Babies born at full term will have the same antibodies that mom has and it can protect the baby up to 1 year of life?
True
What are different types of antibody sources?
provide passive immunity
- Blood products
- any blood product… there are antibodies in it
- Immune globulin
- Taken from 1000 adult donors… has lots of different antibodies.
- Hyperimmune globulins
- High concentration of a spcecific antibodies
- Antitoxin
- Derived from an animal for example horses… so horse is vaccinated and then we will use the antibodies from them. Often times people will experience an adverse reaction to the horse protien.. which can cause serum sickness
What are 2 types of vaccines?
- Live attenuated vaccines
- Inactivated vaccines
What do we need to know about live attenuated vaccines?
- Weakened form of “wild” virus/bacterium
- Must replicate
- Blood products might affect the vaccine from replicating which effects its effectiveness
- Issues with effectiveness
- Damage to organism
- circulating antibody: anything that damages that live organism or interferes with the organisms ability to replicate affects its ability to protect.
- Specific handeling/storage
What are examples of live attenuated vaccines?
- Measles
- Mumps
- Rubella
- Varicella
- Rotavirus
- Intranasal influenza
What do we need to know about inactivated vaccines?
- Produced in a culture media
- Cannot replicate
- Multiple doses
- Less affected by ciruclating antibody
- Blood transfusions can be given at the same time since it doest effect
- Antibody titer diminishes over time
- Booster
What are examples of inactivated vaccines?
- Polio
- Hep A &B
- Rabies
- Influeza
- Acellular pertusis
- Human papillomavirus
- diphtheria
- Tetanus
- Pneumococacal
- Meningocococal
Why are move inactivated vaccines given more than once?
1st dose usually primes the immune system… we start gaining immunity after the 2-3 dose
What factors could cause vaccine failure?
- Age/maternal antibody
- dose
- route
- storage and handling
- nutritional status
- Coexisting disease
- genetics
What information do we need to gather in order to prep for vaccine administration?
- Immunization history
- Should be done at every visit
- Recommened schedule
- Screening
- For contraindications
- discuss benefits/risks
- VIS statements
- After care instructions
- education on s/s to expect and appropritate times to take tylenol and motrin
What are nursing considerations/communications in regards to vaccinations?
- Provide accurate user-friendly information
- Explain they are needed what is going to help prevent
- Parent is expressing concern for childs health
- Be genuine & Empathetic r/t parents concerns
- Avoid judgmental/threatening language
- Be knowledgable
- Give VIS before vaccination & Anwser question
- Be flexible
- Parents may want to spread out vaccines
- Involve parent in minimizing adverse effects
- Rescpect parents ultimate wishes
What documentation must we have for vaccinations?
- Day, month & year of administration
- vaccine manufacturer
- Vaccine lot number
- Name and title of person administering vaccine & Address of facility
- Vaccine information statement
- Route
- Site
- Informed concent
- Vaccine refusal
What are some important issues regarding vaccines?
- Spacing of vaccines
- Interval between doses of same vaccine
- timing of antibody-containing blood products
- Live Vaccines: If given to close together it can alter the effectiveness of the vaccine
- inactivated vaccines: not typically affected - Screening
- Idenitfy contraindications/precautions: usuing standardized screening forms
Allergy to vaccine or component is it contraindicated in live attenuated and/or inactivated?
Live: Contraindicated
Inactivated: Contraindicated
Encephalophathy: Is it contraindiated to give a live attenuated or inactivated vaccine?
Live: —
Inactivated: Contraindicated
Pregnancy: is it contraindicated to give a live attenuated or inactivated vaccine?
Live: Contraindicated
Inactivated: Vaccinate w/some exceptions
immunosuppression: Is it contraindicated to give a live attenuated or inactivated vaccine?
Live: Contraindicated
Inactivated:Vaccinate with some exceptions
Moderate to severe illness: Is it contraindicated to give a live attenuated or inactivated vaccine?
Live: Precaution
Inactivated: Precaution
Recent blood products: Is it contraindicated to give live attenuated or inactivated vaccines?
Live: Precaution
Inactivated: Vaccinate
What are some common misconceptions/myths with vaccinations?
Invalid “contraindications”
1. Mild Illness
2. antimicrobial therapy
3. preganant or immunosuppressed person in the househould
4. breastfeeding- Okay with all but NOT small pox
5. Preterm Birth: Must be atleast 2 kilos
6. Allergy to products not in vaccine: important to know whats in the vaccine
7. Multple vaccines: No evidence.. but it is important to keep on tract.
What are some local reactions to vaccines?
- Mild/self-limited
- Pain/swelling/redness at injection site
- Within hours of injection
- Common with inactivated vaccines
What are some systemic reactions to vaccinations?
- Fever/malaise/headache/myalgia/loss of appetite
- Reactions following live vaccines may be simiular to mild form of disease
- Can occur 7-21 days after the vaccine administration
How long should we observe a patient for adverse events after a vaccine
15 mins
What should we do if a patient has a adverse event?
- Vaccine adverse event reporting system (VAERS)
- Any clinically significant adverse event
- Even if you are unsure if the vaccine caused it
Which vaccines are given subQ?
- MMR (measles, mumps, rubella)
- Varicella
What vaccines are given intramusclular?
- dTaP/Tdap (diphtheria, tetanus, aceullar pertussis
- Hep a
- Hep B
- HIB (Haemophilus influenzae type B)
- HPV (Human papillomavirus)
- IPV (Inactivated polio vaccine) IM or sub Q
- PCV (Pneumococcal vaccine) IM or sub Q
- MCV (Meningococcal vaccine) IM or sub Q
Do we aspirate w/ vaccinations?
Aspiration not required w/vaccines
1. No reports of injury
2. Veins/Arteries too small to allow IVP of vaccine
3. Study in canada: Patient expereienced less pain when vaccine given rapidly w/out aspiration.
What should we take in consideration with children with bleeding disorders and vaccinations?
- Potential for hematoma with IM injection
- Physician needs to be made aware if not already
- Hemophilia- Factor replacement? Will need to know when there last dose of factor replacement was
- 23 gauage or finer needle
- Firm pressure for 2 miniutes
- Do not rub/massage site
How do we provide atraumatic care when giving vaccinations?
- Distraction that is developmentally appropriate
- Parent cuddling/holding, pacifiers
- Sweet tasting solutions (oral sucrose)
- Breastfeeding
- Injection technique
- Order of injections
- Tactile stimulation (rub/stroke near injection site/buzzy)
- Topical anesthetic
What are some different types of communicable diseases?
- Pertusis
- chicken pox
- Rubeola
- Mumps
- Rubella
- Scarlet fever
- Coronavirus/ Covid 19
What is a macule?
Flat discoloration of skin
What is a papule?
Solid raised lesion on skin
What is a vesicular?
Fluid filled sac
What is maculopapular?
Raised discolored lesion
How is pertusis (whooping cough) spread?
- Respiratory secrtions (direct/indirect)
- Most contagious during the Catarrhal stage
What are the s/s of pertusis (whooping cough) during the Catarrhal stage
Catarrhal stage
1. Respiratory symptoms
2. Low grade fever
3. Last 1-2 weeks