unit 10: endocrine system Flashcards
endocrine glands
ductless
function= synthesize and secrete hormones
ex: pituitary gland secretes growth hormone
isolated endocrine cells in other tissue/organs
ex: the Leydig cells in the testes secrete testosterone
Neurons – secrete neurohormones that circulate in the blood
E.g.1: neurons in the hypothalamus secrete several different
“releasing hormones”, like Growth Hormone Releasing Hormone
(GHRH) that act on the anterior pituitary gland.
Properties of hormones: More than one hormone can be produced in a single endocrine gland
E.g.1: the pituitary gland synthesizes and secretes 6 different
hormones.
Properties of hormones: Different tissues can secrete the same hormone
E.g.1: The hypothalamus and the pancreas secrete somatostatin (an inhibitory hormone)
Properties of hormones: A single hormone can act on multiple different target cells in
different organs
E.g.1: epinephrine and norepinephrine released by the
adrenal gland can act on cells in the heart, blood vessels,
airways of the respiratory tract, etc
Properties of hormones: Multiple hormones can bind to receptors and produce responses
in a single target cell.
norepinephrine, epinephrine, angiotensin, and vasopressin
can all act on the smooth muscle cells of blood vessels to regulate
blood flow and blood pressure
Properties of hormones: Hormone secretion can vary over time and can be affected by
changes in the environment
E.g.1: Circadian rhythms involved in release of cortisol and
melatonin. Cortisol secretion from adrenal gland peaks in the early
morning and decreases at night
Properties of hormones: Hormones have a half life =length of time required to reduce
hormone concentration in the blood by half
a) Single amino acid derived hormones = minutes
b) Peptide and protein hormones = minutes to hours
c) Steroid hormones = hours
Hormones control
Metabolism
Ø Reproduction
Ø Growth and development
Ø Water and electrolyte balance
Ø Digestion and absorption of nutrients
Ø Blood cell production and development
Ø Etc.
Ø i.e. hormones regulate homeostasis.
Hormones function by controlling the
- rates of enzymatic reactions in cells
- transport of ions or molecules across cell membranes
- gene expression and protein synthesis.