Unit 1 Quiz

Question 1

Serum proteins that increase in concentration within 24 to 48 hours of the onset of infection or injury are called:

(a) reagins
(b) immunoglobulins
(c) complement proteins
(d) acute-phase proteins

Answer 1

(d) acute-phase proteins

Question 2

The purpose of negative selection of B cells is to:

(a) Eliminate B cells that don’t express mu.
(b) Prevent activation of B cells in the bone marrow.
(c) Direct more B cells to become plasma cells.
(d) Eliminate B cells that are specific for self-antigens

Answer 2

(d) Eliminate B cells that are specific for self-antigens

Question 3

Which is a characteristic of circulating neutrophils?

(a) Kill cells with granzymes
(b) Membranes express antigen-specific receptors
(c) Membranes express pathogen receptors
(d) Activated by Alpha-1-antitrypsin

Answer 3

(c) Membranes express pathogen receptors

Question 4

Which immunoglobulin appears first in the primary response?

(a) IgG
(b) IgM
(c) IgA
(d) IgE

Answer 4

(b) IgM

Question 5

Multiple cytokines are activated to cause similar biological effects. What is this process called?

(a) Pleiotropy
(b) Redundancy
(c) Synergism
(d) Antagonism

Answer 5

(b) Redundancy

Question 6

T lymphocytes undergo antigen-independent maturation in the:

(a) Thymus
(b) Bone marrow
(c) Lymph node
(d) Spleen

Answer 6

(a) Thymus

Question 7

What is the major function of C-reactive protein?

(a) Opsonization
(b) Binding hemoglobin
(c) Causing vasodilation
(d) Promoting clot formation

Answer 7

(a) Opsonization

Question 8

Predominant cell types involved in the humoral immune responses are:

(a) Eosinophils
(b) Macrophages
(c) Neutrophils
(d) B cells

Answer 8

(d) B cells

Question 9

All of the following cells are considered part of innate, natural immunity EXCEPT?

(a) Eosinophils
(b) B lymphocytes
(c) Monocytes
(d) Neutrophils

Answer 9

(b) B lymphocytes

Question 10

The internal defense system includes which of the following?

(a) Cilia
(b) Mucous membranes
(c) Acute-phase reactants
(d) Acidity of the skin

Answer 10

(c) Acute-phase reactants

Question 11

The receptor for antigen on a mature naïve B cell is:

(a) Class I MHC
(b) Class II MHC
(c) IgG
(d) IgM

Answer 11

(d) IgM

Question 12

Antibodies are secreted by:

(a) Plasma cells
(b) B cells
(c) T cells
(d) Dendritic cells

Answer 12

(a) Plasma cells

Question 13

Which factors are only associated with the alternative pathway?

(a) Factor B and Factor D
(b) Factor D and C3
(c) Factor B and C2
(d) C2 and MBL

Answer 13

(a) Factor B and Factor D

Question 14

Which of the following is part of the external defense system?

(a) Ceruloplasmin
(b) Skin
(c) Neutrophils
(d) Complement

Answer 14

(b) Skin

Question 15

Which acute-phase reactant is an important clotting factor?

(a) Haptoglobin
(b) Ceruloplasmin
(c) Fibrinogen
(d) Alpha-2 macroglobulin

Answer 15

(c) Fibrinogen