Unit 1: Histology Flashcards
Basement membrane
Thin layer of fibrous material that anchors epithelial tissue to connective tissue
Histology
Study of tissues and how they form organs
Tissue
Group of similar cells and cell products
Organ
2 or more tissues working together
Types of tissues
Epithelial, connective, muscle, nervous
Hist
Tissue
Squam
Flat
Gen
To create
Fibro
Fiber
Striat
Striped
Chondr
Cartilage
Blast
To create
Cardi
Heart
Neuro
Nervous system
Describe composition of epithelial tissue: Composition Where Layers Shapes
Composition: 1+ layers of flat packed cells and little ECM
Where: upper surface faces external environment or body cavity
Layers: simple (1 layer)
stratified (2+ layers)
pseudostratified (simple but appears stratified)
Shapes: squamous (flat)
cuboidal (square)
columnar (rectangular)
Appearance and function of squamous cells
Flat and scale like
Allow for rapid diffusion and secretes serous fluid
Appearance and function of cuboidal cells
Square
Absorbs and secretes
Produces mucus
Appearance and function of columnar cells
Rectangular
Absorbs and secretes
Secretes mucus
Ciliated
What tissue are glands?
Epithelial tissue
Define exocrine glands
Maintain connection to the surface with ducts
Define endocrine glands
Have no ducts, directly secrete hormones into bloodstream
Define basement membrane
Anchors epithelium to underlying connective tissue with collagen and proteins
Define avascular
Depends on connective tissue for oxygen from blood
Functions of epithelium
Protect Absorb Filtrate Excrete Secrete Sensory reception
Name 3 glands and their secretions
Serous - thin watery (tears, digestive juices, sweat)
Mucous - thick glycoprotein mucin (mucus)
Cytogenic - release whole cells (sperm or egg cells)
Define intercellular junction
Anchors cells to each other or to the ECM
Functions and characteristics of desmosomes
Strong
Connect cells and hold against mechanical stress
Gaps filled with mesh
Functions and characteristics of tight junctions
Weak
Creates barrier over cells and prevents substances between cells, joins to surrounding cells
Functions and characteristics of gap junctions
Channels
Aid in cell communication
Water-filled channels formed from trans membrane proteins, substances pass directly from cell to cell
Describe composition of connective tissue:
Widely spaced cells with large extra cellular matrix
Ground substance
Gelatinous or rubbery material between cells
ECM is made up of
Ground substance and fibers
Functions of connective tissue
Connect structures Support Protect Store energy Transport materials
Ground substance is made of
Proteoglycans and adhesive glycoproteins
Most common and variable tissue
Connective tissue
3 fibers in connective tissue
Collagen, reticular, and elastic
Describe collagen fibers
Made of collagen protein
Very strong
Flexible but do not stretch
Where would you find collagen fiber?
Tendons, ligament, dermis
Describe reticular fibers
Thin collagen fibers coated with glycoprotein
Create a web or frame
Where would you find reticular fibers?
Spleen, lymph nodes
Describe elastic fibers
Thin, branching fibers made of elastin
Stretch and recoil
Where would you find elastin?
Skin, heart, lungs
What are the main types of cells in connective tissue?
Blast cells
White blood cells
Mast cells
Adipocytes
Define blast cells
Mitotic cells which secrete ground substance and fibers
What do fibroblasts produce?
Protein fibers and ground substance
Where would you find chondroblasts?
Cartilage
Where would you find osteoblasts?
Bone
What do hemocytoblasts produce and where?
Blood cells
Bone marrow
What is the function of white blood cells?
Immune system
What are mast cells and what do they do?
Cells that produce heparin (inhibits clotting) and histamine (dilates blood cells)
What do adipocytes do?
Store fat
________ connective tissue contains gel-like substance between cells with few fibers
Loose
_____ connective tissues have many fibers which fill the space between cells
Dense
Name the types of connective tissue:
Adipose, areolar, cartilage, bone, blood, reticular
Describe adipose tissue and it’s location
Loose
Store energy and provide cushioning and insulation
Located in subcutaneous fat under skin and visceral fat surrounding organs
Describe areolar tissue and where it’s found
“Packing material” Loose and fibrous Very common Support and bind tissues Hold bodily fluids Defend against infection Found under dermis and under epithelial tissue
Describe reticular tissue and where it’s found
Loose
Made of reticular fibers and ground substance
“Net” that supports other cells
Found in bone marrow, lymph nodes, spleen
Describe bone tissue
Dense
Can be spongey or compact
Describe cartilage, it’s types, and where it’s found
Dense
Supportive with rubbery matrix
No blood vessels
Fibrocartilage - strong cartilage that resists compression
Pubic symphysis and intervertebral discs
Hyaline - dispersed collagen
Flexible
Joints, larynx, trachea
Elastic - flexible but maintains shape
More elastin than hyaline
Ear, epiglottis
Describe blood
Liquid connective tissue
Contains white and red blood cells and platelets
Function of muscular tissue
Long cells which exert force on other tissues
Contract to move, push substances, pump blood
Types of muscular tissue
Skeletal, cardiac, smooth
Describe skeletal muscle
Long, cylindrical
Multiple nuclei
Voluntary
Striated
Describe cardiac muscle
Short, branched
1 nucleus
Striated
Involuntary
Describe smooth muscles
Short Not striated 1 nucleus Create sheets of muscle “Push” substances
Describe nervous tissue and it’s components
Conductive and secrete
Large neurons with dendrite and axon send messages
Small glial cells protect neurons
Found in brain, spinal cord, nerves, ganglia
Describe mucous membranes and where they are found
Made up of epithelial and connective tissue with underlying muscle
Line passageways exposed to exterior with mucus
Found in digestive, respiratory, urinary, and reproductive tracts
Describe cutaneous membranes
“Protect”
Skin atop connective tissue
Dry membrane
Describe synovial membranes
Lines and lubricates joints
Connective tissue which secretes synovial fluid
Describe serous membranes
“Glide”
Protects and lines outside of organs and body cavities
Produce serous fluid