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LAT > Unit 1 Exam: Ch 1-4 > Flashcards

Unit 1 Exam: Ch 1-4 Flashcards

1
Q

What is the primary federal granting agency through which the United States conducts and supports biomedical research?

A

National Institues of Health (NIH)

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2
Q

What is an animal use protocol?

A

A detailed explanation of a research project involving animals

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3
Q

What does the Institutional Animal Care and Use Committee (IACUC) do?
A- review animal use protocols
B- conduct inspections of animal facilities and reviews institutional animal use programs at least every 6 months
C- serve as an information and resource liaison on animal welfare and research concerns
D- all of the above

A

D- all of the above

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4
Q

What is the purpose of the IACUC’s protocol review?

A

A postapproval monitoring program that helps ensure the IACUC-approved procedures are being followed

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5
Q

Which statement regarding the postapproval monitoring (PAM) program is true?
A- a PAM program is mandated by law
B- a PAM program is typically under the control of the attending veterinarian
C- a PAM program helps ensure that IACUC approved procedures are being followed
D- the staff of the PAM program decides what punitive actions are required if deficiencies are noted

A

C- a PAM program helps ensure that IACUC approved procedures are being followed

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6
Q

A systematic investigation to establish facts is the definition of what term?

A

Research

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7
Q

What is the correct name for the acronym IACUC?
A- informational Animal Care and Use Committee
B- Institutional Animal Care and Use Council
C- Instiutional Animal Care and Use Committee
D- Institutional Animal Costs and Use Committee

A

C- Institutional Animal Care and Use Committee

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8
Q

What is the name of the paperwork necessary to request research money?

A

Grant application

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9
Q

What documentation is required before an investigator can begin a study using animals?

A

IACUC approval of the animal use protocol

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10
Q

Which feature must be provided for nonhuman primates as required by the Animal Welfare Act (AWA)?

A

Psychological enrichment

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11
Q

What document must an institution have before the Public Health Service (PHS) will award a grant or contract that involves the use of animals?

A

An approved Animal Welfare Assurance

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12
Q

What must an institution housing USDA- covered animals do annually as required by the Animal Welfare Regulations (AWR)?

A

Submit a report

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13
Q

According to the Guide, how often must the IACUC conduct the facility inspections and program review?

A

At least once per year

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14
Q 
Which animal is covered under the Animal Welfare Act (AWA)?
A- Guinea pigs
B- Poultry
C- Birds
D- Horses not used for research
A

A- Guinea pigs

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15
Q

Good Laboratory Practices (GLP) regulations are most likely to be maintained for which type of study?

A

Food, drug, or environmental safety

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16
Q

What is an Animal Welfare Assurance?

A

An agreement from a research institution outlining how it complies with the Public Health Service Policy

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17
Q

Which word is used in the Guide to describe aspects of an animal care program that are essential or imperative to the proper humane care and use of laboratory animals?

A

Must

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18
Q

How often does the AAALAC perform site visits of accredited institutions?

A

Every 3 years

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19
Q

What must a facility create and follow as required by GLP Regulations?

A

Standard Operating Procedures (SOP)

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20
Q

Who is responsible for monitoring a study and ensuring compliance with GLPs?

A

Quality assurance unit (QAU)

21
Q 
Which animals below are covered under the Public Health Service (PHS) Policy's?
A- all vertebrate animals
B- all invertebrate animals
C- all vertebrates except mice
D- all vertebrates and invertebrates
A

A- All vertebrate animals

22
Q

What is a requirement to maintain AAALAC accreditation?
A- an inspection report from the USDA
B- An annual report by the institution that describes changes to the animal care and use program
C- a $500 certification fee
D- proof of animal welfare training being offered every 6 months

A

B- an annual report by the institution that describes changes to the animal care and use program

23
Q

What is the purpose of having standard operating procedures?

A

To ensure uniformity in animal care

24
Q

What is the correct name for the acronym AAALAC?

A

Association for assessment and accreditation of laboratory animal care

25
Q

Which USDA pain category would correspond with experiments, teaching, research, experiments, or tests causing pain or distress to the animals, for which appropriate anesthetic, analgesic, or tranquilizing drugs were used?

A

Category D

26
Q

What resource provides guidelines for programs that use agricultural animals for agricultural research or teaching?

A

Guide for the care and use of agricultural animals in research and training

27
Q

Which organization publishes the guidelines on euthanasia?

A

American veterinary medical association (AVMA)

28
Q

Which of the 3R principles is addressed if nonanimal alternatives are used instead of animals?

A

Replacement

29
Q

Which of the following is an example of the 3Rs principle of replacement?
A- adding environmental enrichment to a cage
B- providing anesthesia after surgery
C- using computer models to provide data
D- using rats instead of mice

A

C- using computer models to provide data

30
Q

What is the general term for the policy at an institution that protects individuals from reprisal if the report a problem?

A

Whistleblower policy

31
Q

What term refers to the concept that the way people behave is based on commonly held core values?

A

Ethics

32
Q

According to the Guide, what is the term defined as the actions taken to assure that laboratory Nimals are treated according to high ethical and scientific standards?

A

Humane care

33
Q

When fewer animals are used Ina study, which of the 3Rs principles is being applied?

A

Reduction

34
Q

What term refers to knowing and following the rules?

A

Compliance

35
Q

In the decision-making process, which step would come before gathering and accessing all the facts involved?

A

Identify the issue of concern

36
Q

What is the aim of ethical decisions?

A

For a balance of cost and benefits for human and animals

37
Q

When organizing your to-do list, how would you prioritize tasks?

A

In order of importance and deadline demands

38
Q

What is included in the health record for a nonhuman primate?

A

Physical exams

39
Q

How long are all assurance records related to NIH-funded grants to be maintained?

A

At least 3 years free completion of the study

40
Q

Which is an example of a centralized management system?
A- the main facility is run by one department and satellite facilities are run by the primary investigation group
B- each department maintains its own facility
C- expenditures and records involving animals are maintained by a separate department that serves all the institution’s animal care needs
D- each department is responsible for its own animal care staffing

A

C- expenditures and records involving animals are maintained by a separate department that serves all the instituion’s animal care needs

41
Q 
What is an example of a direct cost?
A- animals
B- maintenance
C- equipment depreciation
D- security
A

A- animals

42
Q 
Which expense is an example of an indirect cost?
A- bedding
B- animals
C- feed
D- telephone system
A

D- telephone system

43
Q

If each department within an institution maintains its own animal facility and operating budget, it is considered what type of management system?

A

Decentralized

44
Q

What is a cost center?

A

An activity that has expenses but does not directly produce revenue

45
Q

What should you do after you delegate a task?

A

Follow up to be sure it has been completed

46
Q 
Which of the following is important whe working with co-workers?
A- listening
B- clear communication
C- conflict resolution
D- all of the above
A

D- all of the above

47
Q

Per diem costs are the expenses required to maintain one animal or one cage of animals for how long?

A

1 day

48
Q

If it costs $54,750 per year to maintain 100 rats, what would the per diem cost?

A

54750/365/100 = $1.50

49
Q 
Which time kept onsite requires a current DEA license?
A- cleaners
B- toxic substances
C- anesthetics
D- controlled substances
A

D- controlled substances

LAT (23 decks)

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