Unit 1 Exam: Ch 1-4 Flashcards
What is the primary federal granting agency through which the United States conducts and supports biomedical research?
National Institues of Health (NIH)
What is an animal use protocol?
A detailed explanation of a research project involving animals
What does the Institutional Animal Care and Use Committee (IACUC) do?
A- review animal use protocols
B- conduct inspections of animal facilities and reviews institutional animal use programs at least every 6 months
C- serve as an information and resource liaison on animal welfare and research concerns
D- all of the above
D- all of the above
What is the purpose of the IACUC’s protocol review?
A postapproval monitoring program that helps ensure the IACUC-approved procedures are being followed
Which statement regarding the postapproval monitoring (PAM) program is true?
A- a PAM program is mandated by law
B- a PAM program is typically under the control of the attending veterinarian
C- a PAM program helps ensure that IACUC approved procedures are being followed
D- the staff of the PAM program decides what punitive actions are required if deficiencies are noted
C- a PAM program helps ensure that IACUC approved procedures are being followed
A systematic investigation to establish facts is the definition of what term?
Research
What is the correct name for the acronym IACUC?
A- informational Animal Care and Use Committee
B- Institutional Animal Care and Use Council
C- Instiutional Animal Care and Use Committee
D- Institutional Animal Costs and Use Committee
C- Institutional Animal Care and Use Committee
What is the name of the paperwork necessary to request research money?
Grant application
What documentation is required before an investigator can begin a study using animals?
IACUC approval of the animal use protocol
Which feature must be provided for nonhuman primates as required by the Animal Welfare Act (AWA)?
Psychological enrichment
What document must an institution have before the Public Health Service (PHS) will award a grant or contract that involves the use of animals?
An approved Animal Welfare Assurance
What must an institution housing USDA- covered animals do annually as required by the Animal Welfare Regulations (AWR)?
Submit a report
According to the Guide, how often must the IACUC conduct the facility inspections and program review?
At least once per year
Which animal is covered under the Animal Welfare Act (AWA)? A- Guinea pigs B- Poultry C- Birds D- Horses not used for research
A- Guinea pigs
Good Laboratory Practices (GLP) regulations are most likely to be maintained for which type of study?
Food, drug, or environmental safety
What is an Animal Welfare Assurance?
An agreement from a research institution outlining how it complies with the Public Health Service Policy
Which word is used in the Guide to describe aspects of an animal care program that are essential or imperative to the proper humane care and use of laboratory animals?
Must
How often does the AAALAC perform site visits of accredited institutions?
Every 3 years
What must a facility create and follow as required by GLP Regulations?
Standard Operating Procedures (SOP)
Who is responsible for monitoring a study and ensuring compliance with GLPs?
Quality assurance unit (QAU)
Which animals below are covered under the Public Health Service (PHS) Policy's? A- all vertebrate animals B- all invertebrate animals C- all vertebrates except mice D- all vertebrates and invertebrates
A- All vertebrate animals
What is a requirement to maintain AAALAC accreditation?
A- an inspection report from the USDA
B- An annual report by the institution that describes changes to the animal care and use program
C- a $500 certification fee
D- proof of animal welfare training being offered every 6 months
B- an annual report by the institution that describes changes to the animal care and use program
What is the purpose of having standard operating procedures?
To ensure uniformity in animal care
What is the correct name for the acronym AAALAC?
Association for assessment and accreditation of laboratory animal care
Which USDA pain category would correspond with experiments, teaching, research, experiments, or tests causing pain or distress to the animals, for which appropriate anesthetic, analgesic, or tranquilizing drugs were used?
Category D
What resource provides guidelines for programs that use agricultural animals for agricultural research or teaching?
Guide for the care and use of agricultural animals in research and training
Which organization publishes the guidelines on euthanasia?
American veterinary medical association (AVMA)
Which of the 3R principles is addressed if nonanimal alternatives are used instead of animals?
Replacement
Which of the following is an example of the 3Rs principle of replacement?
A- adding environmental enrichment to a cage
B- providing anesthesia after surgery
C- using computer models to provide data
D- using rats instead of mice
C- using computer models to provide data
What is the general term for the policy at an institution that protects individuals from reprisal if the report a problem?
Whistleblower policy
What term refers to the concept that the way people behave is based on commonly held core values?
Ethics
According to the Guide, what is the term defined as the actions taken to assure that laboratory Nimals are treated according to high ethical and scientific standards?
Humane care
When fewer animals are used Ina study, which of the 3Rs principles is being applied?
Reduction
What term refers to knowing and following the rules?
Compliance
In the decision-making process, which step would come before gathering and accessing all the facts involved?
Identify the issue of concern
What is the aim of ethical decisions?
For a balance of cost and benefits for human and animals
When organizing your to-do list, how would you prioritize tasks?
In order of importance and deadline demands
What is included in the health record for a nonhuman primate?
Physical exams
How long are all assurance records related to NIH-funded grants to be maintained?
At least 3 years free completion of the study
Which is an example of a centralized management system?
A- the main facility is run by one department and satellite facilities are run by the primary investigation group
B- each department maintains its own facility
C- expenditures and records involving animals are maintained by a separate department that serves all the institution’s animal care needs
D- each department is responsible for its own animal care staffing
C- expenditures and records involving animals are maintained by a separate department that serves all the instituion’s animal care needs
What is an example of a direct cost? A- animals B- maintenance C- equipment depreciation D- security
A- animals
Which expense is an example of an indirect cost? A- bedding B- animals C- feed D- telephone system
D- telephone system
If each department within an institution maintains its own animal facility and operating budget, it is considered what type of management system?
Decentralized
What is a cost center?
An activity that has expenses but does not directly produce revenue
What should you do after you delegate a task?
Follow up to be sure it has been completed
Which of the following is important whe working with co-workers? A- listening B- clear communication C- conflict resolution D- all of the above
D- all of the above
Per diem costs are the expenses required to maintain one animal or one cage of animals for how long?
1 day
If it costs $54,750 per year to maintain 100 rats, what would the per diem cost?
54750/365/100 = $1.50
Which time kept onsite requires a current DEA license? A- cleaners B- toxic substances C- anesthetics D- controlled substances
D- controlled substances
