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LAT > Chapter 2: Policies, Guidlines, And Regulations In Animal Research > Flashcards

Chapter 2: Policies, Guidlines, And Regulations In Animal Research Flashcards

1
Q

True or False

The USDA requires that common laboratory rodents are shipped with a health certificate

A

False

One must accompany a dog, cat, or nonhuman primate

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2
Q

True or False

Specific state regulations on the sale and shipment of dogs exist because of distemper vaccination requirements

A

False

Regulations exist because of rabies vaccination requirements

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3
Q

The Guide for the Care and Use of Laboratory Animals (the guide) is an important source of information on animal care and use program management and is endorsed by the text Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International as one of its standards for the accreditation of laboratory animal programs

A

True

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4
Q

Who registers institutions using species covered by the Animal Welfare Act (AWA)

A

USDA

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5
Q

Who requires compliance with the Good Laboratory Practices (GLPs)

A

FDA

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6
Q

Who describes what a facility must do to comply with the Animal Welfare Act (AWA)

A

AWR

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7
Q

Who publishes the Policy on the Humane Vare and Use of Laboratory Animals

A

PHS

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8
Q

Who provides peer evaluation of animal care and use programs

A

AAALAC

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9
Q

According to the American Veterinary Medical Association (AVMA) Guidelines on Euthanasia, what step must be taken before and animal carcass disposal?

A

Death must be confirmed

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10
Q

A _____ _______ includes the animals or any other entity that is administered a substance.

A

Test system

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11
Q

The ________ __________ is the person responsible for all aspects of a study.

A

Study director

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12
Q

The ___________ ____________ ____________ audits studies to ensure compliance with GLPs.

A

Quality assurance unit

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13
Q

The ________ _________ __________ is a detailed description of a procedure to be performed. These help to ensure standardization of procedures.

A

Standard operation procedure

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14
Q

The observations, measurements, and specimens related to a study are called the ________ ________.

A

Raw data

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15
Q

The two federal agencies that require compliance with the GLPs are the _________ and the ________.

A

Environmental protection agency

Food and drug administration

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16
Q

How many biosafety levels are described in the Biosafety in Microbiological and Biomedical Laboratories (BMBL)?

A 
4
1- BSL-1
2- BSL-2
3- BSL-3
4- BSL-4
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17
Q

The word ______ is used in the Guide to describe aspects of a program that are essential or imperative to humane care and use of laboratory animals.

A

Must

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18
Q

The word ______ is used in the Guide to describe aspects of a program that are strong recommendations to achieve a goal.

A

Should

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19
Q

Which document is used by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) and the United States Depratment of Agriculture (USDA) when inspecting agricultural animals used in biomedical research?

A

Guide for the care and use of agricultural animals I research and teaching

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20
Q

What type of animals are covered in Appendix II of the Convention on International trade in Endangered Species of Wild Fauna and Flora (CITES)?

A

Species that are likely to become endangered

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21
Q

What must the institution submit to the United States Department of Agriculture (USDA) each year?

A

Annual report

22
Q

Who conducts an unannounced inspection of registered institutions?

A

USDA veterinary medical officers

23
Q

How often must the institution update its registration with the United States Department of Agriculture (USDA) if using Animal Welfare Act (AWA) covered species?

A

Every 3 years

24
Q

What pain category identifies teaching, experiments, research, surgery, or tests causing pain or distress to the animals, for which appropriate anesthetic, analgesic, or tranquilizing drugs were not used because they would have adversely affected the procedures, results, or interpretation

A

Category E

25
Q

What pain category identifies animals being bred, conditioned, or held for use in teaching, testing, experiments, research, or surgery, but not yet used for such purposes

A

Category B

26
Q

What pain category identifies teaching, research, experiments, or tests conducted that cause no pain or distress and thus do not require the use of pain-relieving drugs

A

Category C

27
Q

What pain category identifies experiments, teaching, research, experiments, or tests causing pain or distress to the animals, for which appropriate anesthetic, analgesic, or tranquilizing drugs were used

A

Category D

28
Q

What is the classification of a person who raises and sells purpose-bred animals

A

Class A dealer

29
Q

What is the classification of a person who purchases and resells animals

A

Class B dealer

30
Q

What agency enforces the PHS Policy?

A

Office of Laboratory Animal Welfare (OLAW)

31
Q

What document is signed by the Institutional Official (IO) and is filed to commit the institution to compliance with the PHS Policy?

A

Animal Welfare Assurance

32
Q

What animals are covered under the PHS Policy?

A

All vertebrates

33
Q

What is a requirement of AWA/AWR.

A
  • minimum of 3 members on the IACUC
  • they conduct inspections annually
  • enforced for USDA, APHIS
34
Q

What are requirements of PHS Policy?

A
  • covers all vertebrate animals
  • enforced by OLAW
  • minimum of 5 members on the IACUC
  • inspections are for cause
35
Q

What key words best fit US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training I

A

Compliance with the Animal Welfare Act

36
Q

What key words best fit US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training II

A

Relevance to health or society

37
Q

What key words best fit US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training III

A

Selection of animals

38
Q

What key words best fit US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training IV

A

Proper use of animals

39
Q

What key words best fit US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training V

A

Managing pain or distress

40
Q

What key words best fit US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training VI

A

Euthanasia

41
Q

What key words best fit US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training VII

A

Animals’ living conditions

42
Q

What key words best fit US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training VIII

A

Personnel qualifications and experience

43
Q

What key words best fit US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training IX

A

Handling exceptions to the Principles

44
Q

True or False:

The safety and emotional reactions of personnel are not a consideration in euthanasia methods.

A

False

They are considerations

45
Q

True or False

The AVMA’s term for recommended methods of euthanasia is “ideal”

A

False

“Acceptable”

46
Q

The AVMA’s term for methods that should not be used is “unacceptable”

47
Q

For research animals, the euthanasia method must be described in the protocol and approved by the IACUC

48
Q

What is the name of the reference document used for guidance on occupational health and safety programs?

A

Occupational health and sFety in the care and use of research animals

49
Q

True or False

All institutions are required to have the same occupational health and safety program

A

False

It varies among institutions

50
Q

True or False
An occupational health and safety program should reflect the nature of the work and the health and safety needs of personnel

51
Q

True or False
A training program on occupational health and safety should be comprehensive for the risks likely to occur in the institution

52
Q

True or False

Small institutions are exempt from the requirements for an occupational health and safety program

A

False

No institution is exempt

LAT (23 decks)

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