Guide For The Care & Use Of Laboratory Animals

Question 1

Which statement describes the concept of refinement?
A- strategies that result in the same scientific outcomes with using fewer animals per experiment
B- using non-animal methods of obtaining scientific data
C- strategies that result in procedures that enhance anima wellbeing and minimize pain and distress
D- using invertebrate animas instead of vertebrate animals in research

Answer 1

C- strategies that result in procedures that enhance animal wellbeing and minimize pain and distress

Question 2

What is an engineering standard?

Answer 2

A guideline that specifies in detai a method or technique for achieving a desired outcome

Question 3

How does the Guide describe a Policy?

Answer 3

A practical statement of collective wisdom

Question 4

Which of the following describes the Guide’s definition of “should”?
A- an action that is considered mandatory
B- a suggestion to be considered
C- a strong recommendation
D- a general guideline

Answer 4

C- a strong recommendation

Question 5

According to the Guide, which member is NOT required on the IACUC?
A- veterinarian 
B- committee chair
C- scientist
D- a general guideline

Answer 5

B- committee chair

Question 6

Which of these tasks is a function of the IACUC?
A- submitting inspection reports to the facility veterinarian
B- conducting the animal census
C- inspecting animal facilities
D- determining per diem rates

Answer 6

C- inspecting animal facilities

Question 7

The IACUC should meet at least how often?

Answer 7

As often as necessary to fulfill its obligations

Question 8

What does the acronym IACUC stand for?

Answer 8

Institutional Animal Care and Use Committee

Question 9

Which topic should be considered in the preparation and review of an animal care and use protocol?
A- unnecessary duplication of experiments and method of euthanasia
B- the animal vendor used and delivery method
C- current animal census and per diem rates
D- animal technician scheduling

Answer 9

A- unnecessary duplication of experiments and method of euthanasia

Question 10

Which statement is an important guideline when using physical restraints?
A- restraint devices are not to be considered normal methods of housing
B- animals must be able to eat and drink while being restrained
C- restraint must not exceed 12 hours under any circumstances
D- veterinary staff must be present while the animal is being restrained

Answer 10

A- restraint devices are not to be considered normal methods of housing

Question 11

Which statement about major survival surgery is NOT true?
A- major survival surgery includes any procedure conducted under anesthesia
B- whether a procedure is considered “major” may be decided by the IACUC and veterinarian, for non-USDA covered species
C- major survival surgery may include laparoscopic surgery
D- major survival surgery includes any surgical procedure that produces substantial pain

Answer 11

A- major survival surgery includes any procedure conducted under anesthesia

Question 12

Which statement is a valid justification for allowing multiple major survival surgeries?
A- the surgeries are related components of a esearch project
B- it wil save the investigators time
C- the animals used are very expensive
D- the investigator wants to reuse the animal on a new protocol

Answer 12

A- the surgeries are related components of a research project

Question 13

If an animal of a species covered by the Animal Welfare Act has undergone one major survival surgery, and an investigator requests to use the animal on a different protocol which includes another major survival surgery, what agency must approve this?

Answer 13

USDA

Question 14

Animals on a fluid regulation protocol should have their body weights recorded at least how often?

Answer 14

Once a week

Question 15

Who is responsible for providing formal or on-the-job training to personnel for animals?

Answer 15

The institution

Question 16

True or False
Non-degree training, such as certification programs for laboratory animal technicians and technologists, is an accepted means for obtaining qualifications for working with laboratory animals.

Answer 16

True

Question 17

The extent and level of participation of personnel in the occupational health and safety program depends on all of the following except:
A- the hazards posed by the animals
B- exposure intensity
C- susceptibility of personnel
D- personnel employment status

Answer 17

D- personnel employment status

Question 18

All of the following are important parts of an occupational health program EXCEPT:
A- pre-employment healthy evaluation
B- appropriate immunization schedule
C- collection and storage of blood serum samples for all employees
D- early diagnosis of allergies

Answer 18

C- collection and storage of blood serum samples for all employees

Question 19

All of the following are recommended for personnel working with nonhuman primates, EXCEPT:
A- access to antibiotic drugs
B- access to a bite and scratch kit
C- instruction in the proper use of a bite kit
D- tuberculosis screening

Answer 19

A- access to antibiotic drugs

Question 20

When conducting scientific research using hazardous biological agents, what publication should be consulted and followed?

Answer 20

Biosafety in Microbiological and Biomedical Laboratories

Question 21

Who should be involved in determining the humane endpoints in a study?

Answer 21

IACUC, the veterinarian, and the PI

Question 22

When is it permissible to use non-pharmaceutical grade substances on animals?

Answer 22

When permission is granted from the IACUC

Question 23

Whic of the following should NOT be included in the facility’s disaster plan?
A- how the facility will protect irreplaceable animals
B- how the facility will prevent animal pain and distress if the HVAC system fails
C- how the facility will provide animals with potable water in the case of a disaster
D- how the facility will prevent the use of expired anesthetic and analgesics on animals

Answer 23

D- how the facility will prevent the use of expired anesthetic and analgesics on animals

Question 24

The majority of poikilothermic laboratory animals are:

Answer 24

Fish and aquatic amphibians

Question 25

If ventilated caging has adequate filters, the air exhausted from the caging may be returned into the room, although it is generally preferred that the air be vented to:

Answer 25

The facility’s exhaust system

Question 26

Which of the following is NOT part o the micro environment in an animal room?
A- shoebox cage
B- bedding 
C- food
D- biological safety cabinet

Answer 26

D- biological safety cabinet

Question 27

Animals can adapt to temperature extremes by al of the following mechanisms EXCEPT: 
A- pharmacological
B- physical
C- behavioral
D- metabolic

Answer 27

A- pharmacological

Question 28

What is the recommended number of air changes per hour in an animal room?

Answer 28

10 to 15