Final Exam Flashcards

1
Q

Which body approves the animal use protocol before animals can be used for research?

A

Institutional Animal Care and Use Committee

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2
Q

How many Institutional Animal Care and Use Committee (IACUC) members does Public Health Service (PHS) Policy require?

A

5

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3
Q

What does the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) endorse as one of its standards for the accreditation of animal laboratory programs?

A

Guide for the Care and Use of Laboratory Animals

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4
Q

What are animal dealers that raise and sell animals themselves licensed as?

A

Class A

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5
Q

How often do both the Public Health Service (PHS) and the Animal Welfare Regulations (AWR) require that the Institutional Animal Care and Use Committee (IACUC) conduct inspections of the animal facilities and study areas? How often does the Guide state that inspections should be conducted?

A

At least every 6 months; at least once per year

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6
Q

Which of the following is included in the Good Laboratory Practice (GLP) Regulations?
A- The requirement for facilities to relate and adhere to standard operating procedures (SOPs)
B- Specifications on how raw data should be handled
C- The requirement that archives must be maintained
D- All of the above

A

D- All of the above

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7
Q

Which of the four parts of the Animal Welfare Regulations (AWR) list requirements and procedures for research institutions and dealers working with Animal Welfare Act (AWA)- covered species?

A

Regulations

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8
Q

Which of the following, while not a regulation, has regulatory authority for institutions conducting Public Health Service (PHS)-supported activities in animal research programs?
A- Guide for the Care and Use of Laboratory Animals
B- Guidelines for the Humane Transportation of Research Animals
C- Occupational Health andSafety in the Care and Use of Research Animals
D- Biosafety in Microbiological and Biomedical Laboratories

A

A- Guide for the Care and Use of Laboratory Animals

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9
Q

According to the American Veterinary Medical Association (AVMA) Guidelines on euthanasia, what must be confirmed before disposal of a body of an animal?

A

Death

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10
Q

If an investigator searches for a technique that will cause animals less distress, which of he 3 R principles is being applied?

A

Refinement

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11
Q

What is TRUE in a systematic process of ethical decision making?
A- factors the research staff view as important are primarily considered
B- it is best to have one or two people discuss and decide on an action
C- all important factors are considered
D- decisions must be made primarily based on financial consideration

A

C- all important factors are considered

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12
Q

What is the type of management program called in which each department is responsible for its own animal care staffing?

A

Decentralized management program

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13
Q

What is the term that refers to the cost charged to maintain one unit, either one animal or one cage of animals, for one day?

A

per dime rate

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14
Q

How many years does the Public Heath Service (PHS) require that protocol records be kept after completion of a study?

A

3 years

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15
Q
Which of the following is not a sterilizer?
A- vaporized hydrogen peroxide
B- chorine dioxide gas
C- quaternary ammonium compounds
D- peracetic acid
A

C- quarternary ammonium compounds

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16
Q

Which biological safety cabinet provides maximum protection for the worker and the environment outside the cabinet?

A

class III

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17
Q

Which of the following is FALSE about hazardous material?
A- the protocol must specify information about the hazard
B- animal technicians should use appropriate personal protective equipment when handling animal wastes containing hazardous materials
C- animals given hazardous substances can be kept in the same cage as animals that are not given hazardous substances
D- personnel working with animals dosed with gamma-emitting radioisotopes are monitored with film badges

A

C- animals given hazardous substances can be kept in the same cage as animals that are not given hazardous substances

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18
Q

What is the relative room humidity required by semi aquatic and terrestrial amphibian species?

A

50-80% or greater

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19
Q

What type of filtration involves passing water over activated charcoal?

A

Chemical

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20
Q

Which system maintains low levels of nitrogen and algae and conserves water?

A

Recirculating

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21
Q

What is the process of gas exchange between an organism and its environment?

A

Respiration

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22
Q

What is the name of a structure that contains at least two different types of tissue?

A

Organ

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23
Q

What component of a cell contains the genetic material?

A

Nucleus

24
Q

What is the passive movement of solvent molecules across the cell membrane called?

A

Osmosis

25
Q

What is the technical name for a nerve cell?

A

Neuron

26
Q

What is the term for preserving a genetic line by freezing embryos, sperm cells, or ovaries?

A

Cryopreservation

27
Q

Which fulfills the concepts of the 3Rs in breeding colonies?
A- choosing the appropriate genotype of animals to mate together
B- calculating the number of offspring of each genotype that will result
C- preventing unplanned mating
D- all of the above

A

D- all of the above

28
Q

In pigs, what does the term farrowing mean?

A

Giving birth

29
Q

Which type of breeding produces animals with minimal genetic variation?

A

Inbreeding

30
Q

A cat weighing 4kg is to given a 15 mg/kg dose of antibiotic. The antibiotic comes in a concentration of 20 mg/mL. How may mL will you administer?

A

3.0 mL

31
Q

A prescription is written for 360 mg of a drug. The drug comes in a concentration of 40 mg/mL. How many mL would you draw up into the syringe?

A

9 mL

32
Q

What is the amount of a drug administered per unit of body weight?

A

Dosage

33
Q
Which of the following can deuce accidental needle sticks?
A- hypodermic needles
B- transdermal needs-free injectors
C- syringe slip tips
D- tuberculin syringes
A

B- transdermal needs-free injectors

34
Q
Which of the following CANNOT be determined when using a dipstick for urinalysis?
A- pH
B- presence of blood
C- blood type
D- protein level
A

C- blood type

35
Q

What may be indicated by the presence of white blood cells in urine?

A

Kidney or badder infection

36
Q

What are the two classifications of animal cancer models?

A

Induced and spontaneous

37
Q

What test is used as an alternative to the use of rabbits for the detection of pyrogens?

A

Limulus amebocyte lysate (LAL) test

38
Q

Which of the following is FALSE about immunocompromised animals?
A- they may have a poor appetite
B- they may have difficulty drinking
C- they may take longer to recover from wounds and ailments
D- they may be kept in open-to cages

A

D- they may be kept in open-top cages

39
Q

Why are synthetic suture materials preferred?

A

They cause little inflammatory reaction

40
Q

What happens to nonabsorbable sutures in the body?

A

They do not break down in the body

41
Q
Which can be used in place of sutures to close a wound?
A- gauze pads
B- wound clips
C- retractor
D- hemostatic forceps
A

B- wound clips

42
Q

How often should you repeat scrubbing a surgical site?

A

3 times

43
Q

How does the Guide define major surgery?

A

Entering or exposing a body cavity or causing permanent disability or physiologic change

44
Q

Which of the following is FALSE about nonsurvival surgery?
A- the animal must be monitored for appropriate anesthetic depth
B- the instruments must be sterilized
C- fur needs to be clipped from around the surgical site
D- gloves should be worn

A

B- the instruments must be sterilized

45
Q

What are the clinical signs of ataxia?

A

Loss of coordination and ability to control movements

46
Q

In what part of the body does otitis occur?

A

Ears

47
Q
Which of the following conditions may occur in frogs?
A- Q-fever
B- B virus
C- red leg
D- barbering
A

C- red leg

48
Q

Which statement is FALSE about anesthetic emergencies?
A- oxygen administration may be necessary in cases of cardiac or respiratory distress
B- clear communication is helpful in coordinating response by personnel to the situation
C- knowledge of emergency drugs and ther effects on the body is valuable in managing animals in this situation
D- SOPs are seldom usefu for managing these types of emergencies

A

D- SOPs are seldom useful for managing these types of emergencies

49
Q

Which of the following is FALSE about giving birth?
A- an animal in labor should be checked on often and quietly
B- it is important to have an idea of how long contractions have been going on for
C- a veterinarian should be called if labor does not progress normally
D- dystocia is a routine occurrence for most animals

A

D- dystocia is a routine occurrence for most animals

50
Q

What is the first action a technician should take for an animal discovered bleeding profusely from a a wound on its shoulder?

A

Apply pressure to the site to limit blood loss

51
Q

When using an adenosine triphosphate (ATP) detection test, what does the presence of ATP in a sample indicate about the surface it came from?

A

The surface was not adequately cleaned

52
Q

Which type of disease is characterized by a sudden outbreak affecting a large number of animals?

A

Endemic

53
Q

Which of the following is FALSE about a decentralized management program?
A- each department that uses animals is responsible for getting its own supplies
B- each department that uses animals is managed by one supervising department
C- each department that uses animals has its own operating budget
D- each department that uses animals maintains its own facility

A

B- each department that uses animals is managed by one supervising department

54
Q
Which system provides the framework of the body?
A- integumentary
B- skeletal
C- muscular
D- endocrine
A

B- skeletal

55
Q
What controls sexual reproduction?
A- pituitary gland and gonads
B- hormones
C- chemicals in the body
D- all of the above
A

D- all of the above

56
Q

Which of the following is true regarding aseptic surgical procedures?
A- the procedures are the same for nonsurvival surgery s for survival surgery
B- they are required for all vertebrate animals expected to recover from the anesthesia
C- these procedures ensure absolute sterility in the surgical room
D- a dedicated operating room is required for major survival surgery on rodents to ensure asepsis

A

C- these procedures ensure absolute sterility in the surgical room

57
Q

What type of mating system occurs when 2 or more females are bred with 1 male and the females are removed from the mating cage once they are determined to be pregnant?

A

Polygamous mating