Final Exam Flashcards
Which body approves the animal use protocol before animals can be used for research?
Institutional Animal Care and Use Committee
How many Institutional Animal Care and Use Committee (IACUC) members does Public Health Service (PHS) Policy require?
5
What does the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) endorse as one of its standards for the accreditation of animal laboratory programs?
Guide for the Care and Use of Laboratory Animals
What are animal dealers that raise and sell animals themselves licensed as?
Class A
How often do both the Public Health Service (PHS) and the Animal Welfare Regulations (AWR) require that the Institutional Animal Care and Use Committee (IACUC) conduct inspections of the animal facilities and study areas? How often does the Guide state that inspections should be conducted?
At least every 6 months; at least once per year
Which of the following is included in the Good Laboratory Practice (GLP) Regulations?
A- The requirement for facilities to relate and adhere to standard operating procedures (SOPs)
B- Specifications on how raw data should be handled
C- The requirement that archives must be maintained
D- All of the above
D- All of the above
Which of the four parts of the Animal Welfare Regulations (AWR) list requirements and procedures for research institutions and dealers working with Animal Welfare Act (AWA)- covered species?
Regulations
Which of the following, while not a regulation, has regulatory authority for institutions conducting Public Health Service (PHS)-supported activities in animal research programs?
A- Guide for the Care and Use of Laboratory Animals
B- Guidelines for the Humane Transportation of Research Animals
C- Occupational Health andSafety in the Care and Use of Research Animals
D- Biosafety in Microbiological and Biomedical Laboratories
A- Guide for the Care and Use of Laboratory Animals
According to the American Veterinary Medical Association (AVMA) Guidelines on euthanasia, what must be confirmed before disposal of a body of an animal?
Death
If an investigator searches for a technique that will cause animals less distress, which of he 3 R principles is being applied?
Refinement
What is TRUE in a systematic process of ethical decision making?
A- factors the research staff view as important are primarily considered
B- it is best to have one or two people discuss and decide on an action
C- all important factors are considered
D- decisions must be made primarily based on financial consideration
C- all important factors are considered
What is the type of management program called in which each department is responsible for its own animal care staffing?
Decentralized management program
What is the term that refers to the cost charged to maintain one unit, either one animal or one cage of animals, for one day?
per dime rate
How many years does the Public Heath Service (PHS) require that protocol records be kept after completion of a study?
3 years
Which of the following is not a sterilizer? A- vaporized hydrogen peroxide B- chorine dioxide gas C- quaternary ammonium compounds D- peracetic acid
C- quarternary ammonium compounds
Which biological safety cabinet provides maximum protection for the worker and the environment outside the cabinet?
class III
Which of the following is FALSE about hazardous material?
A- the protocol must specify information about the hazard
B- animal technicians should use appropriate personal protective equipment when handling animal wastes containing hazardous materials
C- animals given hazardous substances can be kept in the same cage as animals that are not given hazardous substances
D- personnel working with animals dosed with gamma-emitting radioisotopes are monitored with film badges
C- animals given hazardous substances can be kept in the same cage as animals that are not given hazardous substances
What is the relative room humidity required by semi aquatic and terrestrial amphibian species?
50-80% or greater
What type of filtration involves passing water over activated charcoal?
Chemical
Which system maintains low levels of nitrogen and algae and conserves water?
Recirculating
What is the process of gas exchange between an organism and its environment?
Respiration
What is the name of a structure that contains at least two different types of tissue?
Organ
What component of a cell contains the genetic material?
Nucleus
What is the passive movement of solvent molecules across the cell membrane called?
Osmosis
What is the technical name for a nerve cell?
Neuron
What is the term for preserving a genetic line by freezing embryos, sperm cells, or ovaries?
Cryopreservation
Which fulfills the concepts of the 3Rs in breeding colonies?
A- choosing the appropriate genotype of animals to mate together
B- calculating the number of offspring of each genotype that will result
C- preventing unplanned mating
D- all of the above
D- all of the above
In pigs, what does the term farrowing mean?
Giving birth
Which type of breeding produces animals with minimal genetic variation?
Inbreeding
A cat weighing 4kg is to given a 15 mg/kg dose of antibiotic. The antibiotic comes in a concentration of 20 mg/mL. How may mL will you administer?
3.0 mL
A prescription is written for 360 mg of a drug. The drug comes in a concentration of 40 mg/mL. How many mL would you draw up into the syringe?
9 mL
What is the amount of a drug administered per unit of body weight?
Dosage
Which of the following can deuce accidental needle sticks? A- hypodermic needles B- transdermal needs-free injectors C- syringe slip tips D- tuberculin syringes
B- transdermal needs-free injectors
Which of the following CANNOT be determined when using a dipstick for urinalysis? A- pH B- presence of blood C- blood type D- protein level
C- blood type
What may be indicated by the presence of white blood cells in urine?
Kidney or badder infection
What are the two classifications of animal cancer models?
Induced and spontaneous
What test is used as an alternative to the use of rabbits for the detection of pyrogens?
Limulus amebocyte lysate (LAL) test
Which of the following is FALSE about immunocompromised animals?
A- they may have a poor appetite
B- they may have difficulty drinking
C- they may take longer to recover from wounds and ailments
D- they may be kept in open-to cages
D- they may be kept in open-top cages
Why are synthetic suture materials preferred?
They cause little inflammatory reaction
What happens to nonabsorbable sutures in the body?
They do not break down in the body
Which can be used in place of sutures to close a wound? A- gauze pads B- wound clips C- retractor D- hemostatic forceps
B- wound clips
How often should you repeat scrubbing a surgical site?
3 times
How does the Guide define major surgery?
Entering or exposing a body cavity or causing permanent disability or physiologic change
Which of the following is FALSE about nonsurvival surgery?
A- the animal must be monitored for appropriate anesthetic depth
B- the instruments must be sterilized
C- fur needs to be clipped from around the surgical site
D- gloves should be worn
B- the instruments must be sterilized
What are the clinical signs of ataxia?
Loss of coordination and ability to control movements
In what part of the body does otitis occur?
Ears
Which of the following conditions may occur in frogs? A- Q-fever B- B virus C- red leg D- barbering
C- red leg
Which statement is FALSE about anesthetic emergencies?
A- oxygen administration may be necessary in cases of cardiac or respiratory distress
B- clear communication is helpful in coordinating response by personnel to the situation
C- knowledge of emergency drugs and ther effects on the body is valuable in managing animals in this situation
D- SOPs are seldom usefu for managing these types of emergencies
D- SOPs are seldom useful for managing these types of emergencies
Which of the following is FALSE about giving birth?
A- an animal in labor should be checked on often and quietly
B- it is important to have an idea of how long contractions have been going on for
C- a veterinarian should be called if labor does not progress normally
D- dystocia is a routine occurrence for most animals
D- dystocia is a routine occurrence for most animals
What is the first action a technician should take for an animal discovered bleeding profusely from a a wound on its shoulder?
Apply pressure to the site to limit blood loss
When using an adenosine triphosphate (ATP) detection test, what does the presence of ATP in a sample indicate about the surface it came from?
The surface was not adequately cleaned
Which type of disease is characterized by a sudden outbreak affecting a large number of animals?
Endemic
Which of the following is FALSE about a decentralized management program?
A- each department that uses animals is responsible for getting its own supplies
B- each department that uses animals is managed by one supervising department
C- each department that uses animals has its own operating budget
D- each department that uses animals maintains its own facility
B- each department that uses animals is managed by one supervising department
Which system provides the framework of the body? A- integumentary B- skeletal C- muscular D- endocrine
B- skeletal
What controls sexual reproduction? A- pituitary gland and gonads B- hormones C- chemicals in the body D- all of the above
D- all of the above
Which of the following is true regarding aseptic surgical procedures?
A- the procedures are the same for nonsurvival surgery s for survival surgery
B- they are required for all vertebrate animals expected to recover from the anesthesia
C- these procedures ensure absolute sterility in the surgical room
D- a dedicated operating room is required for major survival surgery on rodents to ensure asepsis
C- these procedures ensure absolute sterility in the surgical room
What type of mating system occurs when 2 or more females are bred with 1 male and the females are removed from the mating cage once they are determined to be pregnant?
Polygamous mating
