Unit 1: Autoimmune Diseases 1

Question 1

What is the key cytologic feature of patients with pemphigus complex?

Answer 1

Acantholytic keratinocytes (and non-degenerate neutrophils)

Question 2

What type of pemphigus rarely reveals acantholytic cells?

Answer 2

vulgaris

Question 3

What appearance does P. vulgaris have?

Answer 3

Tombstone appearance

Question 4

What is the target for PF?

Answer 4

Desmocollin 1

Question 5

What is the target for PV?

Answer 5

Desmoglein 3

Question 6

What is the most common AI disease in dogs and cats?

Answer 6

PF

Question 7

What are drug-induced causes of PF?

Answer 7

Cephalosporins, sulfonamides, and amitraz-containing products

Question 8

What is the primary lesion of PF?

Answer 8

Pustules spanning multiple follicular units or interfollicular

Question 9

What is the primary lesion for PV?

Answer 9

Vesiculobullous lesions rapidly progressing to erosions and ulcerations

Question 10

What is the location of disease with PF?

Answer 10

Head, face, ears, nasal planum, paw pads, claw folds (cats)

Question 11

What is the location of disease with PV?

Answer 11

Oral cavity and mucocutaneous lesions;

May involve paw pads or claw beds