Unit 1: Alopecic Disorders of Dogs & Cats Flashcards

1
Q

What is the cuticle?

A

Outermost layer that has a fish scale appearance, is up to 10 layers thick

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the cortex?

A

Middle layer where the pigment is contained;

Clear appearance, contributes to sheen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the medulla?

A

Innermost layer of vacuated cells;

Degeneration of glycogen that builds up and contributes to sheen;

Contributes to insulating capability

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the bulb?

A

Active part of the follicle that causes growing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the isthmus?

A

Middle portion of the follicle that is affected by some AI diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the bulge of the follicle?

A

Area where the sebaceous glands empty into

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the infundibulum of the follicle?

A

Opening surface down to where the sebaceous glands open

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the hair cycle?

A

Anagen –> Catagen –> Telogen –> Exogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

_____ is the active growing phase.

A

anagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

_____ is the transition from growing to non-growing hairs.

A

catagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

____ is the resting phase.

A

telogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Majority of hairs in dogs and cats are in _____ phase.

A

telogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

_____ is active shedding of the follicle.

A

exogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What growth phase is this?

A

telogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What growth phase is this?

A

anagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What should the ratio of telogen : anagen be?

A

10-20 : 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What hormones stimulate hair growth?

A

Thyroid, melatonin, growth hormone, androgens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What hormones inhibit hair growth?

A

Cortisol, estrogen, progesterone, prolactin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What breed is this and why are they hairless?

A

Chinese Crested - autosomal dominant trait

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What breed is this and why are they hairless?

A

Mexican hairless - autosomal dominant trait

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What happens if the Mexican Hairless has homozygous dominant alleles?

A

It is lethal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What breed is this and what is special about them?

A

Peruvian Inca Orchid - oldest dog breed on record

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What breed is this and why are they bred for?

A

American Hairless Terrier;

Bred for “hyperallergenicity” but allergens are actually in the saliva not the hair

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What breed is this and what are the characteristics?

A

Devon Rex;

Primary hairs resemble secondary hairs

Whiskers absent or stubbled

Bald ventral surfaces

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What breed is this and what are the characteristics?

A

Cornish Rex;

Lack primary hairs, whiskers are short and curly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

What breed is this and what are the characteristics?

A

Sphinx;

Have hair follicles and hair fiber

hair doesn’t form normally, fracture before they get to the surface

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

What alopcic conditions are not treatable?

A

X-linked/Congenital, canine pattern alopecia, Black Hair Follicular Dysplasia, Color Dilution Alopecia, Breed-Specific Acquired Alopecia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What is X-linked/Congenital alopecia?

A

Genetic mutation with ectodermal differentiation, recessive x-linked gene (males affected)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What are characteristics of congenital alopecia?

A

Varying degrees affecting the head, scral resion, abdomen, and proximal extremities

30
Q

What are characteristics of canine pattern alopecia?

A

Onset of 6 months, ventral type vs. pinnal type (3-5 yo) vs. alopecia/melanoderma of the Yorkie

31
Q

What is the treatment for canine pattern alopecia?

A

None; it is a cosmetic problem

32
Q

What are characteristics of black hair follicular dysplasia/color dilution alopecia?

A

Affects black hair or dilute colors - Dobermans, Silver Labs

33
Q

How is black hair dysplasia/color dilution alopecia diagnosed?

A

Trichogram - clumping of melanin –> weakening and fracturing of hair

34
Q

What breeds get Breed Specific Acquired Alopecia?

A

Chesapeake bay Retrievers, Curly-Coated Retrievers, Portuguese Water Dog, Irish Water Spaniel

35
Q

What areas are affected by breed specific alopecia?

A

Flanks, dorsum, rump, caudal thighs

36
Q

What is characteristic of alopecia in the Irish Water Spaniel?

A

Bald neck and tail

37
Q

What alopecic conditions MIGHT be treatable?

A

Canine Recurrent Flank Alopecia, Bald Thigh Syndrome, Alopecia X

38
Q

What is Canine Recurrent Flank Alopecia AKA?

A

Seasonal Flank Alopecia

39
Q

What breeds commonly get seasonal flank alopecia?

A

Boxer, English Bulldog, Airedale Terrier, Schnauzer

40
Q

What are characteristics of seasonal flank alopecia?

A

Onset at 4 yo, rapid onset of well-demarcated flank alopecia and hyperpigmentation

41
Q

How is seasonal flank alopecia diagnosed?

A

History, CS, exclusion, biopsy

42
Q

How can seasonal flank alopecia be treated?

A

Spontaneous regrowth or melatonin to try to prevent episodes from recurring the following year

43
Q

What breed gets bald thigh syndrome?

A

Greyhounds 2-3 yo

44
Q

What is the potential treatment for bald thigh syndrome?

A

Regrowth of hair observed in some cases after racing career has finished

45
Q

What breeds are affected by Alopecia X?

A

Pomeranians, Malamutes, Chows, Keeshonds 1-3 yo

46
Q

What are the CS of Alopecia X?

A

Symmetrical, hyperpigmentation sparing the head and limbs

47
Q

What is the diagnosis for Alopecia X?

A

exclusion

48
Q

What is the treatment for Alopecia X?

A

Benign neglect, neutering, melatonin, pumice stone?

49
Q

What are characteristics of hypothyroidism?

A

Dull/dry/brittle hair, symmetric alopecia, bridge of nose and tail affected, pyoderma and otitis possible, facial myxedema

50
Q

What is the cause of hypoT4?

A

primary most common

51
Q

What tests can be used to diagnose hypoT4?

A

tT4, fT4, TSH, TgAA

52
Q

What CBC findings are consistent with hypoT4?

A

Normocytic, normochromic, non-regen anemia

53
Q

What chem findings are consistent with hypoT4?

A

hypercholesterolemia, hypertriglyceridemia, elevated ALT/CK

54
Q

What diagnostic is normal in hypoT4?

A

U/A

55
Q

What characteristics are associated with Cushing’s?

A

Generalized alopecia, thin skin, comedones, calcinosis cutis, pyoderma

56
Q

What is Cushing’s caused by?

A

Pituitary or adrenal tumor

57
Q

What tests are used to diagnose Cushing’s?

A

LDDS (slower), ACTH stim (faster, $$)

58
Q

What CBC findings are consistent with Cushing’s?

A

Leukocytosis, neutrophilia, lymphopenia, eosinopenia, thrombocytosis

59
Q

What chem findings are consistent with Cushing’s?

A

Elevated ALP +/- ALT

60
Q

What U/A findings are consistent with Cushing’s?

A

Low USG, bacteriuria, elecated UCCR ratio

61
Q

What is the treatment for Cushing’s?

A

Trilostane or Mitotane

62
Q

What are characteristics of hyperestrogenism?

A

Alopecia of abdomen, thighs, perineal region

Linear preputial dermatosis = pathognomonic

63
Q

Feminization is more common with _____.

A

cryptorchids

64
Q

What causes hyperestrogenism?

A

Ovarian cysts/tumors, diethylstilbestrol administration, Sertoli cell tumors, accidental hormone exposure

65
Q

How is hyperestrogenism diagnosed?

A

Signalment, history, CS, serum estradiol

66
Q

What CBC findings are consistent with hyperestrogenism?

A

Non-regen anemia, leukopenia, thrombocytopenia

67
Q

What diagnostic tests are normal with hyperestrogenism?

A

Chem and UA

68
Q

_____ effluvium is acute onset of hair loss due to antimitotic drugs.

A

anagen

69
Q

_____ effluvium is not as rare, due to stressful event, and hair loss is noted _____ after insult.

A

Telogen; 1-3 months

70
Q

What is post-clipping alopecia?

A

Lack of hair regrowth after close clipping for catheters and surgical sites; NOT disease

71
Q

What breeds are predisposed to post-clipping alopecia?

A

Huskies, Malmutes, Samoyeds, Chows

72
Q

Why does post-clipping alopecia happen?

A

Breeds have prolonged telogen phases, so only “treatment” is to give the hair time to grow back