Unit 1: Alopecic Disorders of Dogs & Cats Flashcards
What is the cuticle?
Outermost layer that has a fish scale appearance, is up to 10 layers thick
What is the cortex?
Middle layer where the pigment is contained;
Clear appearance, contributes to sheen
What is the medulla?
Innermost layer of vacuated cells;
Degeneration of glycogen that builds up and contributes to sheen;
Contributes to insulating capability
What is the bulb?
Active part of the follicle that causes growing
What is the isthmus?
Middle portion of the follicle that is affected by some AI diseases
What is the bulge of the follicle?
Area where the sebaceous glands empty into
What is the infundibulum of the follicle?
Opening surface down to where the sebaceous glands open
What is the hair cycle?
Anagen –> Catagen –> Telogen –> Exogen
_____ is the active growing phase.
anagen
_____ is the transition from growing to non-growing hairs.
catagen
____ is the resting phase.
telogen
Majority of hairs in dogs and cats are in _____ phase.
telogen
_____ is active shedding of the follicle.
exogen
What growth phase is this?
telogen
What growth phase is this?
anagen
What should the ratio of telogen : anagen be?
10-20 : 1
What hormones stimulate hair growth?
Thyroid, melatonin, growth hormone, androgens
What hormones inhibit hair growth?
Cortisol, estrogen, progesterone, prolactin
What breed is this and why are they hairless?
Chinese Crested - autosomal dominant trait
What breed is this and why are they hairless?
Mexican hairless - autosomal dominant trait
What happens if the Mexican Hairless has homozygous dominant alleles?
It is lethal
What breed is this and what is special about them?
Peruvian Inca Orchid - oldest dog breed on record
What breed is this and why are they bred for?
American Hairless Terrier;
Bred for “hyperallergenicity” but allergens are actually in the saliva not the hair
What breed is this and what are the characteristics?
Devon Rex;
Primary hairs resemble secondary hairs
Whiskers absent or stubbled
Bald ventral surfaces
What breed is this and what are the characteristics?
Cornish Rex;
Lack primary hairs, whiskers are short and curly
What breed is this and what are the characteristics?
Sphinx;
Have hair follicles and hair fiber
hair doesn’t form normally, fracture before they get to the surface
What alopcic conditions are not treatable?
X-linked/Congenital, canine pattern alopecia, Black Hair Follicular Dysplasia, Color Dilution Alopecia, Breed-Specific Acquired Alopecia
What is X-linked/Congenital alopecia?
Genetic mutation with ectodermal differentiation, recessive x-linked gene (males affected)