UEA Flashcards
Patient walks in and has developed sore mouth and bleeding gums. She takes these medication:
Aspirin 75mg dispersible tabs, 1 OD
Betahistine 8mg tabs, 1 TDS
Carbamazepine 200mg tabs, 1 BD
Simvastatin 40mg tabs, 1 ON
Which ONE of the following is the MOST appropriate course of action?
A Refer her to the doctor as she may be suffering from carbamazepine side effects
B Sell chlorhexidine 0.5% mouthwash with additional mouth hygiene advice
C Sell Oragel® Dental Gel (benzocaine 10% w/w) with additional mouth hygiene advice
D Suggest an alternative to betahistine which can cause dry mouth leading to sore and bleeding gums
E Tell her to stop the aspirin as bleeding gums leading to soreness is a recognised a side effect of antiplatelet medications
refer as suffering from carbamazapine side effects
The doctors decide to start the patient on a broad spectrum antimicrobial drug which has activity particularly against atypical bacteria.
3. Which ONE of the following antimicrobials would be the MOST appropriate treatment for him?
A Amoxicillin
B Ciprofloxacin
C Clarithromycin
D Co-amoxiclav
E Metronidazole
Clarithrmycin
Which ONE of this patients medications listed below is MOST likely to require temporary discontinuation in view of his Clostridium difficile infection?
A Ferrous sulphate
B Finasteride
C Ibuprofen
D Levothyroxine
E Paracetamol
Ferrous Sulphate
A 45-year old female is is undergoing chemotherapy with moderate emetogenic
potential. She has just received her first dose of CMF; Cyclophosphamide, Methotrexate, 5- Flourouracil as neoadjuvant chemotherapy prior to a mastectomy. You are asked to recommend an antiemetic for management of her acute symptoms.
Which ONE of the following agents is the MOST appropriate choice for this patients chemotherapy-induced nausea and vomiting?
A Chlorpromazine
B Cyclizine
C Droperidol
D Metoclopramide
E Ondansetron
Ondansetron
What age is Bonjela for and why
16 or over
as it contains salicylate (a derivative of aspirin), which is contraindicated in children and adolescents under 16 years of age due to the risk of Reye’s syndrome
Which post surgery analgesic interacts with Dabigatran and why
Tramadol: it causes increases risk of bleeding
What is the preferred NSAID for managing pain in RA
Naproxen
Which ONE of the following is LEAST likely to occur as a result of hypersensitivity to aspirin?
A Angioedema
B Bronchospasm
C Haemorrhagic stroke
D Rhinitis
E Urticaria
Haemorrhagic stroke
What is the maximum dose of Simvastatin when used with Amlodipine. And why
10mg due to risk of rhabdomylosis
Which ONE of the following is MOST likely to reduce this patients serum theophylline levels?
A Use of St Jh Wort for mild depression
B Occasional cannabis use
C Use of diazepam 2mg BD for anxiety
D An alcohol intake of double measure 40% whiskey per day
E Smoking 20 roll ups a day
Smoking: as it induces CYP1A2 reducing its serum conc
What electrolyte imbalance do Beta Agonists create
Hypokalaemia
What electrolyte imbalance does Insulin create
hypokalaemia
What electrolyte imbalance do loop diuretics create
hypokalaemia
What substnace imbalance does timolol cause
Hypoglycaemia
Timolol is a beta-blocker, similar to propranolol, and can have effects on blood glucose regulation.
What substance imbalance does alcohol cause
Hypoglycaemia
Alcohol can inhibit gluconeogenesis (the production of glucose in the liver), especially when consumed on an empty stomach or in moderate to high amounts.
What substance imbalance does propranolol cause
Hypoglycaemia
Propranolol, a non-selective beta-blocker, can mask the symptoms of hypoglycaemia and may also interfere with the liver’s ability to release glucose.
At what age is Guaifenasin, OXymetazoline, Phenylehidrine and Pseudoephedrine spray allowed?
6 and over
What infection do these side effects entail; itching, frothy/ smelly/ yellow-green discharge from vagina
Trichomoniasis Vaginalis
What are the symptoms of Phenelzine? (MOAi)
pale, sweaty, anxious, severe headache, N+V, chest pressure and shortness of breath
How to treat severe community acquired pneumonia
Levofloxacin
What is the most significant reason that staff should avoid handling crushed or broken finasteride tablets?
A Pharyngeal irritation if particles are inhaled
B Risk to the male foetus
C Risk of absorption into semen
D Risk of decreased libido
E The drug is cytotoxic
B Risk to the male foetus
What is neurally mediated syncope
fainting due to drop in blood pressure and reduced blood flow to brain
What would you do if a patient develops neurally mediated syncope after vaccine
elevate legs to allow blood back to brain
Which ONE of the following is NOT licensed for once daily use?
A Aclidinium
B Glycopyrronium
C Indacaterol
D Tiotropium
E Umeclidinium
Aclidinium
Which ONE of the medications is the MOST likely causative agent of her hyponatraemia?
A Aspirin
B Atorvastatin
C Bisoprolol
D Citalopram
E Ramipril
Citalopram
What is red mans syndrome
flushing, itching and dyspnoea (can’t breath well)
What drug can cause red mans syndrome and why
Aspirin 75mg OD
Dalteparin SC 5000 units OD
Felodipine 5mg OD
Gliclazide 80mg OD
Insulin glargine 12 units nocte
Paracetamol PO 1g QDS PRN
Vancomycin IV 1g daily
vancomycin due to rapid infusion rate
Which ONE of the following antibiotics is RARELY associated with C. difficile diarrhoea?
A Ciprofloxacin
B Clindamycin
C Co-amoxiclav
D Cefalexin
E Doxycycline
Doxycycline
What vitamin imbalance does Isoniazide cause
Vitmain b6
What is nicorandil used for
stable angina
What happens when you take phenytoin and levonorgestrel
phenytoin is enzyme inducer, reducing effectiveness of contraception
What antihypertensives cause peripheral oedema
Amlodipine and felodepine
Which of these opioids have a mixed agonist and antagonist opioid receptor activity:
A Alfentanyl
B Diamorphine
C Fentanyl
D Meptazinol
E Methadone
F Morphine
G Pethidine
H Tramadol
Meptazinol
When and why would you Alfentanyl instead of diamorphine in injections
in renal impairment, as opioids like diamorphine have active metabolites that can accumulate due to renal impairment
what colour does doxorubicin make your urine
red
What symptoms does vincristine cause
- peripheral neuropathy (pins and needles),
- constipation
- loss of tendon reflexes
Which medication is related with pulmonary fibrosis.
A Bleomycin
B Cyclophosphamide
C Doxorubicin
D Lomustine
E Melphalan
F Mitomycin
G Paclitaxel
H Vincristine
A Bleomycin
What vitamin deficiency is caused by Wernicks Encapethlopathy
Vitmain B1 (Thiamine)
What is status epilepticus
A seizure lasting more than 5 mins
What is acute treatment for status epilepticus
rectual diazepam
