Infections

Question 1

What are the administration instructions of phenoxymethylpenicillin

Answer 1

empty stomach (1 hour before or 2 hours after)

Question 2

What should the “trough” concentration be for Gentamicin, when used in a multiple daily dose regimen for Endocarditis?
A. <0.5mg/L
B. <1mg/L
C. <2mg/L
D. <5mg/L

Answer 2

B. <1mg/L

Question 3

Mr C has been confirmed to have C. Difficile. You are reviewing his medical history to see if there are any drugs which may need to be stopped, in case they contribute to developing C. Difficile.
Which one of the following drugs below is most likely to contribute to developing C. Difficile?
A. Metronidazole
B. Vancomycin
C. Fidoxamicin
D. Omeprazole

Answer 3

C. Fidoxamicin

Question 4

What is the dose of Pyridoxine B6 for peripheral neuropathy when using Isonazide

Answer 4

Pyroxidine 10mg to 20mg daily

Question 5

Mr P57-years-old has been discussed in an MDT. The consultant is wanting to initiate treatment with Gentamicin on multiple daily dose regimen for the treatment of Endocarditis. What should be the maximum duration of treatment?
A. 3 days
B. 5 days
C. 7 days
D. 14 days

Answer 5

C. 7 days

Question 6

What are metronidazole administration instructions

Answer 6

take with food or just after a meal

Question 7

Which of the following antibiotics is most likely to be associated with causing C.Difficile infection?
A. Clindamycin
B. Doxycycline
C. Lymecycline
D. Metronidazole

Answer 7

A. Clindamycin

Question 7

When is mefloquine contraindicated

Answer 7

• depression / anxiety
• psychiatric symptoms

Question 9

Nitrofurantoin administration instructions

Answer 9

take with or after food

Question 10

Which of the following factors would increase the risk of tendon damage in Miss T while taking ciprofloxacin?

A. Taking oral prednisone daily for the management of rheumatoid arthritis
B. A history of gout
Chapter 5 Quiz BNF Infections
C. Taking oral diclofenac daily for the management of osteoarthritis
D. Age over 55 years
E. A history of osteoporosis

Answer 10

• Corticosteroids
• over 60

Question 11

Which of the following statements regarding Daktarin cream is TRUE?

A. Continue to apply for 5 days after the lesions have cleared
B. Continue to apply for 7 days after the lesions have cleared
C. Continue to apply for 10 days after the lesions have cleared
D. Continue to apply for 14 days after the lesions have cleared
E. Continue to apply for 21 days after the lesions have cleared

Answer 11

C. Continue to apply for 10 days after the lesions have cleared

Question 12

Which tests should be performed 18-24 hours after the first dose of gentamicin?
A. C-reactive protein concentration
B. Audiometry
C. Serum creatinine concentration
D. Serum gentamicin concentration
E. Estimated glomerular filtration rate

Answer 12

D. Serum gentamicin concentration

Question 13

Mrs Shelly is 42-year-old who comes into the pharmacy with a prescription for an antibiotic. She tells you that she has been diagnosed with an exacerbation of chronic bronchitis. She has no allergies and is not taking no other medication.
Which of the following is most likely to be on the prescription?
A. Amoxicillin
B. Cefradine
C. Erythromycin
D. Metronidazole
E. Fusidic acid

Answer 13

A. Amoxicillin

Question 14

Which one of the following antibiotics is least likely to have its absorption and/or efficacy impaired if taken after a meal with an antacid?
A. Ciprofloxacin 250mg tablets
B. Co-amoxiclav 250mg/125mg tablets
C. Flucloxacillin 250mg capsules
D. Phenoxymethylpenicillin 250mg tablets
E. Tetracycline 250mg tablets

Answer 14

B. Co-amoxiclav 250mg/125mg tablets

Question 15

Which is the single most appropriate antibiotic to treat the Clostridium Difficile infection?
A. Co-amoxiclav tablets
B. Co-trimoxazole tablets
C. Doxycycline capsules
D. Erythromycin tablets
E. Vancomycin

Answer 15

E. Vancomycin
and miconazole capsules

Question 16

What antibiotic treats Cushing’s Syndrome

Answer 16

Ketoconazole (specialist use only)

Question 17

A 9-year-old presents at the pharmacy
What is the most appropriate treatment for a 9-year-old with a widespread impetigo infection?
A. Clindamycin
B. Flucloxacillin
C. Fusidic acid
D. Ciprofloxacin
E. AmoxicillinA 9-year-old presents at the pharmacy

Answer 17

B. Flucloxacillin

Question 18

How to treat uncomplicated genital chlamydia

Answer 18

• Azithromycin 1g single dose
• Doxycycline 7 day course

Question 19

A 6-year-old child of average weight has been prescribed Phenoxymethylpenicillin solution 125mg.5mL for cellulitis. There is no dose on the prescription so you decide to contact the doctor.
Which of the following would be the most appropriate dose to recommend?
A. 2.5mL BD
B. 5mL QDS
C. 10mL BD
D. 10mL QDS
E. 20mL BD

Answer 19

D. 10mL QDS

Question 20

What is the 1st line treatment for Threadworm in under 6 months

Answer 20

For children aged 6 months and under, hygiene measures alone are recommended

Question 21

. A 29-year-old woman has been prescribed metronidazole for bacterial vaginosis 500mg BD for 7 days. Her regular ongoing medication includes Tegretol (carbamazepine) 100mg tablets. The patient’s usual dose is one tablet BD.
Which of the following statements in INCORRECT?

A. The dose of metronidazole is within the normal BNF range for the treatment of bacterial vaginosis
B. At this dose metronidazole can increase the plasma concentration of carbamazepine
C. Metronidazole has high activity against anaerobic bacteria and protozoa
D. Metronidazole tablets should be taken with or just after food, and the patient should avoid
alcohol
E. Interactions do not apply to topical metronidazole preparations

Answer 21

B. At this dose metronidazole can increase the plasma concentration of carbamazepine

Question 22

Which antibiotic need to be stopped when experiencing diarrhoea

Answer 22

Clindamycin

Question 23

Why does clindamycin need to be stopped in diarrhoea

Answer 23

is associated in antibiotic associated colitis (which might be fatal)

Question 24

Which Tuberculosis drugs are associated with Liver toxicity

Answer 24

Rifampicin, Rifabutin, Isoniazid and Pyrazinamide

Question 25

Which Tuberculosis drugs are not associated with Liver toxicity

Answer 25

Ethambutol

Question 26

If taking Rifampicin with hormonal contraception, how long do you need to have precaution for after stopping rifampicin

Answer 26

4 weeks