Cardiovascular Flashcards

1
Q

Which of following is an example of a thiazide like diuretic?
- Metolazone
- Triamterene

A

Metolazone

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2
Q

With successful hip replacement operation. He has been discharged with Rivaroxaban 10mg 1 OD for prophylaxis of VTE.
How long would you expect Mr P to take the Rivaroxaban for?
-14 days
- 21 days
- 28 days
- 35 days

A

35 days

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3
Q

Which of the following drugs below could blue urine be associated with?
- Metolazone
- Xipamide
- Amiloride
- Triamterene

A

Triamterene

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4
Q

One of the nurses asks what a patients INR should ideally be if they are to switch over to Apixaban from Warfarin straight away?
- <2
- <2.5
- Between 2 and 3
- >2.5

A

<2

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5
Q

Which of the following drugs below can cause an increased risk of QT prolongation when taken alongside Sotalol?
- Citalopram
- Naproxen
- Digoxin
- Methotrexate

A

Citalopram

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6
Q

Which ONE of the following signs and symptoms is least likely to occur in Reye’s Syndrome?

  • Vomiting
  • Seizures
  • Muscle aches
  • Raised white cell count
  • Delirium
A

Muscle Aches

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7
Q

Which ONE of the following drugs should be omitted in order to have the greatest reduction in risk of complications associated with the insertion of an epidural catheter?
- Candesartan
- Levothyroxine
- Dabigatran
- Gliclazide
- Dalteparin

A

Dabigatran (NAOC)

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8
Q

Mr INR is a 62-year-old man who has been prescribed warfarin to treat myocardial infarction. Whilst working in a community pharmacy, you check his warfarin prescription and ask to see his yellow book.
What is the most appropriate target INR for Mr INR?
- 1.5
- 2.0
- 2.5
- 3.0
- 4.5

A

2.5

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9
Q

Mr DVT has been experiencing recurrent deep-vein thrombosis. He has been taking warfarin for several months. His last three INR readings have been stable at 2.4.
What should his INR target be?
- 2
-2.5
- 3
- 3.5
- 4.5

A

3.5

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10
Q

Which of the following can cause cold extremities
- Carvedilol
- Verapamil
- Diltiazem
- Amlodipine
- Bendroflumethiazide

A

Carvedilol (beta blocker)

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11
Q

Mr KV has suffered from a pulmonary embolism, which is suggested to be as a result of deep vein thrombosis. He has been prescribed Warfarin for the treatment of this pulmonary embolism.
What is the most appropriate target INR level for the warfarin therapy?
A. 2.0
B. 2.5
C. 3.0
D. 3.5
E. 4.0

A

2.5

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12
Q

What is the maximum dose for Ramipril, if eGFR is between 30-60mL/minute/1.73m2.

A

5mg

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13
Q

Which of his medications listed above is most likely to predispose Mr S to digoxin toxicity?

A

Bumetanide:
is a loop diuretic, loop and thiazide diuretics can cause hypokalaemia which predisposes to digoxin toxicity.

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14
Q

Which statement is correct about warfarin?

A. A patient with a prosthetic heart valve requires warfarin for 12 weeks
B. A patient with isolated calf-vein deep-vein thrombosis requires warfarin for 12 weeks
C. A patient who’s acquired a venous thromboembolism from surgery requires warfarin for 1
month
D. A patient who has an unprovoked proximal deep vein thrombosis requires warfarin for at
least 3 months
E. A patient who has atrial fibrillation requires warfarin for 1 month

A

D. A patient who has an unprovoked proximal deep vein thrombosis requires warfarin for at
least 3 months

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15
Q

Warfarin duration for isolated calf vein DVT

A

6 weeks

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16
Q

Warfarin duration forVTE provoked by surgery or other transient factors

A

3 months

17
Q

Warfarin duration for unprovoked proximal DVT or PE

A

at least 3 months

18
Q

Warfarin duration for AF and prosthetic heart valve

A

life

19
Q

Which electrolyte imbalance can cause visual disturbances
A. Hypokalaemia
B. Hyperkalaemia C. Hypernatraemia D. Hypercalcaemia E. Hyponatraemia

A

A. Hypokalaemia

20
Q

Mrs O Mron 42-years-old, has recently had an antenatal appointment, as she has found out she is pregnant. The midwife believes that Mrs O Mron is at high risk of developing pre- eclampsia and writes to the GP advising if they can prescribe Aspirin 150mg to be taken. From what week during the pregnancy would you expect Mrs O Mron to commence a daily dose of 150mg Aspirin?

A. Week 1
B. Week 9
C. Week 12
D. Week 36

A

C. Week 12

21
Q

Which one of the following diuretics is associated with gynecomastia?
A. Furosemide
B. Bumetanide
C. Bendroflumethiazide
D. Eplerenone

A

D. Eplerenone (both potassium sparing do)

22
Q

Which of the following drugs has a potential interaction with cranberry juice?
A. Apixaban
B. Clopidogrel
C. Warfarin
D. Amiodarone

A

Warfarin

23
Q

What a patients INR should ideally be if they are to switch over to Apixaban from Warfarin straight away?
A. <2
B. <2.5
C. Between 2-3
D. >2.5

A

<2

24
Q

Some of the drugs prescribed are to prevent CVD events from occurring again, stable angina.
What statin would you expect to see prescribed for Mr P?

A. Atorvastatin 20mg
B. Simvastatin 20mg
C. Simvastatin 40mg
D. Atorvastatin 80mg

A

Atorvastatin 80mg

25
Q

Which of the beta-blockers below is not classed as water soluble?
A. Atenolol
B. Celiprolol
C. Nadolol
D. Bisoprolol

A

D. Bisoprolol

26
Q

Which of the medications below could possibly be changed to try reduce further attacks of gout?
A. Sildenafil
B. Febuxostat
C. Bendroflumethiazide
D. Amlodipine

A

C. Bendroflumethiazide

27
Q

Mrs L I Pitor has recently been started on Atorvastatin 20mg. She had her LFTs checked before starting treatment.
Assuming there are no signs or symptoms suggestive of hepatotoxicity, when should she next have her LFTs checked again?
A. Within 3 months
B. Within 4 months
C. Within 5 months
D. Within 6 months

A

A. Within 3 months

28
Q

Which of the following counselling points is false regarding Warfarin use?

A. Large amounts of green leafy vegetables should be avoided
B. It is present in milk, therefore should be avoided in breast feeding mothers
C. Patients should be advised to consult their GP if they develop a painful skin rash
D. Patients should make their dentist aware that they take Warfarin before undergoing
dental surgery.

A

B. It is present in milk, therefore should be avoided in breast feeding mothers

29
Q

What electrolyte disturbance would be most likely to occur with co-administration of Trimethoprim and Amiloride?
A. Hypokalaemia
B. Hyperkalaemia
C. Hyponatraemia
D. Hypernatraemia

A

B. Hyperkalaemia

30
Q

Both Amiodarone and Digoxin can increase the risk of bradycardia.
What do manufacturers advise when both drugs are given together?
A. Half the dose of Amiodarone
B. Half the dose of Digoxin
C. Quarter the dose of Amiodarone
D. Quarter the dose of Digoxin

A

B. Half the dose of Digoxin

31
Q

Which one of the following would not need to be carried out as baseline bloods for initiating a statin?
A. Non-fasting lipid profile
B. CRP
C. Renal function
D. TSH

A

B. CRP

32
Q
  1. Which of the following diuretics can be given twice daily, if needed, without risking interfering with sleep?
    A. Metazalone
    B. Bendroflumethiazide
    C. Furosemide
    D. Indapamide
A

C. Furosemide

33
Q

Which of the following drugs/substances is NOT known for causing secondary hypertension?
A. Ciclosporin
B. Leflunomide
C. NSAIDs
D. Progesterone Only Pill

A

D. Progesterone Only Pill