CNS Part 2 Flashcards
What are examples of Non-ergot -derived dopamines
- Pramipexole
- Rotigotine
- Ropinerole
What can Non-ergot -derived dopamines do to blood pressure
Hypotension (pramipexole, rotigotine, ropinerole)
What is the normal OTC age for Codeine sale
12 plus
What are the monitoring requirements for patients taking Antipsychotics
- body weight
- UandE
- FBCs
- Blood lipids
- blood glucose
- pulse
- blood pressure
- ECGs
- Prolactin levels
- LFTs
Which monitoring requirements do antipsychotics not warrant
renal tests
What is the minimum age for Domperidone
12 plus
What is the washout period for imipramine and clomipramine when changing form MAOi
3 weeks
What disorders can lithium cause
Thyroid
What can a symptom of SSRIs or NSAIDs be confused with
SSRIs cause GI bleed can be thought to be heartburn
When should lithium serum conc samples be taken after administration
12 hours
How often should methylphenidate monitoring be done
every 6 months
What does Phenytoin do to blood glucose levels
Hyperglycaemia
How often should lithium monitoring take place
every 6 months
What is the Pneumonic for Benzodiazepines that have a legal driving limit
COLD FeeT
Why take sertraline in the morning
can cause insomnia
Which Tricyclic antidepressants are least sedating
- Imipramine
- Lofepramine
- Nortiptaline
Treatment of Hospital Status epilepticus
- IV Lorazepam (repeated 1 time after 10 mins)
- IV Diazepam
What should happen if patient taking Rivastigmine become dehydrated (N+V)
- stop medication
- change to patch or amend dose
When does Domperidone cause QT interval
when given with lithium
Lisdexamphetamine toxicity symptoms
2 phases:
Phase 1:
alert, paranoid, all body systems full force
Phase 2:
exhausted, seizures, hyperthermia, coma
How to treat derleium in alcohol dependance
Oral lorazepam
Carbamazepine, Phenytoin and Sodium Valproate side effects
- depression
- suicide
- hepatotoxicity
- blood dyscrasia
Which deficiency is Carbamazepine, Phenytoin and Sodium Valproate associated with
- vit D deficiency
How long after dose change or withdrawal from anti-epileptics should you not drive for
6 months after
What colour can levodopa make urine
Red
What colour can amitriptyline make urine
green blue
Which medications should be avoided for depression and why
Amitriptyline
Dosuleptin
(dangerous in overdose)
What can amitriptyline do to blood pressure
Hypotension
Which 2nd Generation anti-psychotics cause the most hyperglycaemia
- Clozapine
- Risperidone
- Olanzapine
- Quetiapine
Which antidepressants decrease efficacy of Tamoxifen
- Fluoxetine
- Paroxetine
