CNS Part 2

Question 1

What are examples of Non-ergot -derived dopamines

Answer 1

• Pramipexole
• Rotigotine
• Ropinerole

Question 2

What can Non-ergot -derived dopamines do to blood pressure

Answer 2

Hypotension (pramipexole, rotigotine, ropinerole)

Question 3

What is the normal OTC age for Codeine sale

Answer 3

12 plus

Question 4

What are the monitoring requirements for patients taking Antipsychotics

Answer 4

• body weight
• UandE
• FBCs
• Blood lipids
• blood glucose
• pulse
• blood pressure
• ECGs
• Prolactin levels
• LFTs

Question 5

Which monitoring requirements do antipsychotics not warrant

Answer 5

renal tests

Question 6

What is the minimum age for Domperidone

Answer 6

12 plus

Question 7

What is the washout period for imipramine and clomipramine when changing form MAOi

Answer 7

3 weeks

Question 8

What disorders can lithium cause

Answer 8

Thyroid

Question 9

What can a symptom of SSRIs or NSAIDs be confused with

Answer 9

SSRIs cause GI bleed can be thought to be heartburn

Question 10

When should lithium serum conc samples be taken after administration

Answer 10

12 hours

Question 11

How often should methylphenidate monitoring be done

Answer 11

every 6 months

Question 12

What does Phenytoin do to blood glucose levels

Answer 12

Hyperglycaemia

Question 13

How often should lithium monitoring take place

Answer 13

every 6 months

Question 14

What is the Pneumonic for Benzodiazepines that have a legal driving limit

Answer 14

COLD FeeT

Question 15

Why take sertraline in the morning

Answer 15

can cause insomnia

Question 16

Which Tricyclic antidepressants are least sedating

Answer 16

• Imipramine
• Lofepramine
• Nortiptaline

Question 17

Treatment of Hospital Status epilepticus

Answer 17

• IV Lorazepam (repeated 1 time after 10 mins)
• IV Diazepam

Question 18

What should happen if patient taking Rivastigmine become dehydrated (N+V)

Answer 18

• stop medication
• change to patch or amend dose

Question 19

When does Domperidone cause QT interval

Answer 19

when given with lithium

Question 20

Lisdexamphetamine toxicity symptoms

Answer 20

2 phases:

Phase 1:
alert, paranoid, all body systems full force

Phase 2:
exhausted, seizures, hyperthermia, coma

Question 21

How to treat derleium in alcohol dependance

Answer 21

Oral lorazepam

Question 22

Carbamazepine, Phenytoin and Sodium Valproate side effects

Answer 22

• depression
• suicide
• hepatotoxicity
• blood dyscrasia

Question 23

Which deficiency is Carbamazepine, Phenytoin and Sodium Valproate associated with

Answer 23

• vit D deficiency

Question 24

How long after dose change or withdrawal from anti-epileptics should you not drive for

Answer 24

6 months after

Question 25

What colour can levodopa make urine

Answer 25

Red

Question 26

What colour can amitriptyline make urine

Answer 26

green blue

Question 27

Which medications should be avoided for depression and why

Answer 27

Amitriptyline
Dosuleptin

(dangerous in overdose)

Question 28

What can amitriptyline do to blood pressure

Answer 28

Hypotension

Question 29

Which 2nd Generation anti-psychotics cause the most hyperglycaemia

Answer 29

• Clozapine
• Risperidone
• Olanzapine
• Quetiapine

Question 30

Which antidepressants decrease efficacy of Tamoxifen

Answer 30

• Fluoxetine
• Paroxetine