Pioneer 2024 May Flashcards
What is xerostomia?
dry mouth, not enough salvia produced
Which of these drugs can cause xerostomia
amitriptyline
aspirin
bisoprolol
gliclazide
metformin
amitriptyline
which of these medications has a serious interaction
-apixaban 5mg twice daily
-bisoprolol 10mg once daily
-digoxin 125micrograms once daily
-GTN 400micrograms spray as directed
-ramipril 5mg once daily
-spironolactone 25mg once daily
-verapamil 80mg once daily
Verapamil and Bisoprolol
(increases risk of CVD events)
Which of these symptoms requires GP when taking estradiol
- acute liver disease
- patient has amenorrhoea
- patient who takes warfarin for a non-mechanical heart valve
- symptoms of vaginal soreness, burning and painful intercourse
- Women aged above 50
- acute liver disease
In relation to ‘sick day’ rules for type I diabetes mellitus, which is the correct piece of advice?
- avoid unhealthy foods such as sugary drinks or ice cream
- drink only clear fluids such as water
- do not adjust your insulin doses
- do not continue taking insulin if you are not eating
- measure your ketones
- measure your ketones
A 65-year-old woman takes methotrexate 10mg weekly for rheumatoid arthritis. She has been maintained on this dose for over a year and her condition is stable.
How often does she need to have her full blood count monitored?
- at least fortnightly
- at least monthly
- at least every twelve weeks
- at least every six months
- at least every year
- at least every twelve weeks
What can colchicine and digoxin cause
increase risk of
- myopathy
- rhabdomylosis
How to treat bollous impetigo with penicillin allergy
Clarithromycin
What is the shelf life of vincristine
18 months
What is a common side effect of Iron tablets
teeth discolouration
What do Omega-3-acid ethyl ester medicines (Omacor/Teromeg 1000mg capsules) increase the risk of in patients with established CVD.
atrial fibrillation
Maximum number of times you can use OTC Tadalafil in 1 week
Once
What is the age range of OTC tranexamic acid
18 to 45
A 4-year-old girl is admitted to hospital. She is diagnosed with non-severe hospital-acquired pneumonia that is treatable with antibiotics. She has NKDA and takes no other medication.
Which of the following is the most appropriate antibiotic for her to take for a 5-day course?
- amoxicillin 250mg/5mL suspension10mL BD - clarithromycin 250mg/5mL suspension- 10mL BD
- co-amoxiclav 125mg/31mg/5mL suspension- 10mL TDS
- doxycycline 100mg capsules – 1 BD
- erythromycin 125mg/5mL suspension- 5mL QDS
- co-amoxiclav 125mg/31mg/5mL suspension- 10mL TDS
Which antibiotic does the MHRA remind healthcare professionals to be vigilant for signs and symptoms of pulmonary and hepatic damage?
- amoxicillin
- doxycycline
- nitrofurantoin
- trimethoprim
- vancomycin
- nitrofurantoin
When is the first dose of the rotavirus vaccine given?
at birth
- at 8 weeks
- at 12 weeks
- at 16 weeks
- at 1 year
- at 8 weeks
Pneumococcal polysaccharide vaccine is an inactivated, 23-valent vaccine that protects against pneumococcal disease caused by Streptococcus pneumoniae.
At what age and over is this vaccine recommended to be given?
- 25 years
- 35 years
- 50 years
- 60 years
- 65 years
- 65 years
Which of the following is a more significant side effect of phenelzine in comparison to sertraline?
- GI disturbances
- Muscle ache
- Nausea
- Postural hypotension
- Skin reactions
- Postural hypotension
At which weight should rivastigmine patches be used in caution in
under 50kg
What is a side effect of Galantamine and what should you do if you experience it
- skin cutaneous reactions (rash)
- stop taking galantamine
After initial testing, at what interval does LFT need to be tested during the first 3 months of taking Sulfasalazine?
- weekly
- fortnightly
- monthly
- every 6 weeks
- at 3 months
- monthly
Which Laxatives to avoid in patients with Dysphagia that are using a starch based thickener, changing the consistency of foods.
Avoid laxatives that PEG-based
- All Macrogols
What age is simple linctus licensed in OTC
12 +
A 52-year-old woman who takes theophylline m/r 200mg twice daily for her asthma begins to develop symptoms of nausea, vomiting and tremor. She is admitted to hospital and following some blood tests is diagnosed with acute theophylline toxicity.
Which of these following medications may have contributed to her admission to hospital?
- amlodipine
- clarithromycin
- diazepam
- doxycycline
- Ramipril
- clarithromycin
What is the maximum amount of mg you can sell of pseudoephedrine OTC
720mg
What electrolytre imbalance can an overdose of Desmopressin lead to
Hyponatraemia
What are common side effects of Desmopressin
- stomach ache
- vomiting
- rash
Which of the following symptoms is NOT typical for someone with an underactive thyroid?
- bradycardia
- brittle nails
- constipation
- heat intolerance
- weight gain
- heat intolerance
Which of the following groups does NOT require a higher daily dose of folic acid?
- women who are taking anti-epileptic medication
- women who are taking thyroid medication
- women who previously had an infant with a neural tube defect
- women with diabetes
- women with sickle-cell disease
- women who are taking thyroid medication
What is the most likely outcome of the patient taking both amoxicillin and methotrexate concurrently?
the patient will be more susceptible to methotrexate toxicit
When should samples be taken after a dose and what target serum-lithium concentration is recommended for acute episodes of mania?
12 hours and 0.8–1 mmol/litre
Which blood test is important to take in the first 6 months of sodium valproate therapy?
Liver function test
Which of these back pain symptoms would NOT require referral to a GP?
- loss of bladder control
- numbness or tingling in the buttocks
- pain lasting for more than one week
- pain that is not relieved on resting
- pain that is worse at night or affecting sleep
- pain lasting for more than one week
What interaction of Citalopram (SSRI) and Methadone
increase QT interval
Which anti-diabetic medication is most likely to cause hypoglycaemia
canagliflozin empagliflozin exenatide gliclazide insulin metformin pioglitazone sitagliptin
gliclazide (less likely sitagliptin)
Which anti diabetic medication is not associated with weight gain and causes hypoglycaemia
Sitagliptin
