CNS Flashcards

1
Q

Lithium Monitoring after start of treatment

A

3 monthly

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2
Q

What colour does entacapone make you urine

A

red/brown

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3
Q

What drug class is duloxetine

A

SNRI

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4
Q

How long does it take for Buspirone to work

A

up to 2 weeks

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5
Q

Over how long does Clozapine need to be withdrawn to reduce symptoms

A

over 1 to 2 weeks

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6
Q

Which of the medications below is likely to have caused Mrs K Alory’s weight gain?

A. Metformin
B. Pizotifen
C. Methylphenidate
D. Semaglutide

A

B. Pizotifen

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7
Q

Which one of the drugs below can be used for the treatment of nocturnal enuresis in children?
A. Citalopram
B. Sertraline
C. Imipramine
D. Duloxetine

A

C. Imipramine

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8
Q

Which of the medicines below is most likely to prompt you to ring the prescriber due to an interaction with the Fluoxetine?
A. Tamoxifen
B. Anastrozole
C. Alendronic Acid
D. Omeprazole

A

A. Tamoxifen

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9
Q

Which antiepilepetic has the longest half life

A

Phenobarbital

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10
Q

A drug is indicated for the short-term relief (two to four weeks only) of anxiety that is severe, disabling, or causing the patient unacceptable distress.
Which of the following is the drug most likely to be?
A. Promethazine
B. Temazepam
C. Methadone
D. Lorazepam
E. Tetrabenazine

A

D. Lorazepam

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11
Q

Treatment with this drug is associated with impulse control disorders, including pathological gambling, binge eating and hypersexuality.
Which of the following is the drug most likely to be?
A. Varenicline
B. Selegiline
C. Apomorphine
D. Promethazine
E. Rasagiline

A

C. Apomorphine

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12
Q

The drug is indicated for conscious sedation for dental procedures 30-60 minutes before procedure.
Which of the following is the drug most likely to be?
A. Lorazepam
B. Promethazine
C. Temazepam
D. Methadone
E. Carbamazepine

A

C. Temazepam

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13
Q

The drug is a potent dopamine-receptor agonist indicated in advanced Parkinson’s disease for patients experiencing ‘off’ periods. The patient must be taught to self-administer the medicine by subcutaneous injection at the first sign if an ‘off’ episode.
Which of the following is the drug most likely to be?
A. Tetrabenazine
B. Selegiline
C. Co-careldopa
D. Apomorphine
E. Bromocriptine

A

D. Apomorphine

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14
Q

What does low sodium do to Lithium serum levels

A

increase

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15
Q

Which migraine prophylactic agent has an interaction with Amiodarone

A

Propranolol

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16
Q

What is the interaction of Lithium and ACE

A

increase conc of lithium

17
Q

What is the interaction between fludrocortisone and methadone

A

increase risk of torse de points

18
Q

What are therapeutic lithium levels

A

0.4 to 1

19
Q

What are therapeutic lithium levels in patients with acute mania

A

0.8 to 1

20
Q

Which drug carries an increased risk of cleft palate when given in the first trimester?
A. Sodium valproate
B. Carbamazepine
C. Topiramate
D. Phenytoin

A

C. Topiramate

21
Q

Which toxicity can sodium valproate cause

A

hepatotoxicity

22
Q

Which electrolyte imbalance causes fall in elderly

A

Hyponatraemia

23
Q

What are red flag symptoms of Ibuprofen

A
  • Diarrhoea
  • vomiting
  • drowsiness
  • muscle twitching
24
Q

How long can domperidone be prescribed for

A

7 days

25
Q

Which SSRI has the highest half life

A

fluoxetine

26
Q

How long can metoclopramide be prescribed for

A

3 days

27
Q

What are withdrawal symptoms of benzodiazepines for anxiety?

A

Weight loss
Loss of appetite
Insomnia
Tinnitus
Tremor

28
Q

Which test is not needed when starting lithium

A

Hepatic function

29
Q

1st Line anti-epileptic for children

A
  • Levatiractam
30
Q

What is the serious skin condition associated with Galantamine?
A. Steven-Johnson Syndrome
B. Seborrhoic eczema
C. Kawasaki Disease
D. Shingles

A

A. Steven-Johnson Syndrome

31
Q

Which of the following anti-epileptics has a long half-life?
A. Perampanel
B. Sodium Valproate
C. Levetiracetam
D. Ethosuximide

A

A. Perampanel