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STEP1: GI > UC > Flashcards

UC Flashcards

1
Q

Possible etiology

A

Autoimmune

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2
Q

Location

A

Colitis: colonic and continuous

always rectal involvement

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3
Q

Gross morphology

A

Mucosal and submucosal inflam only
Fiable mucosal pseudopolyps with free hanging mesentery

Loss of haustra: leadpipe appearance on imaging

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4
Q

Microscopic

A

Crypt abscess and ulcer
Bleeding
No granuloma (TH2 mediated vs. Crohns)

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5
Q

Complication

A

Malnutrition,
Sclerosis cholangitis
Toxic megacolon
Colorectal carcinoma (worse with R sided or pancolitis)

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6
Q

Intestinal manifestation

A

Bloody diarrhea

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7
Q

Extraintestinal manifestations

A 
Pyroderma gangrenosum
(vs. erythema nodosom of crohns)
1' scleorsing cholangitis
Ankylosing spondylitis
Uveitis
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8
Q

Treatment

A

ASA prep (sulfasalazine)
6-Mercaptopurine
Infliximab
Colectomy.

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STEP1: GI (62 decks)

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