Osmotic laxatives Flashcards
1
Q
Names
A
Magnesium hydroxide
Magnesium citrate
polyethylene glycol
lactulose
2
Q
MOA
A
Provide osmotic load to draw water out
Lactulose also treats hepatic encephalopathy since gut flora degrade into metabolite (lactic and acetic acid) that promotes nitrogen excretion as NH4+
3
Q
Clinical use
A
Constipation
4
Q
Toxicity
A
Diarrhea
Dehydration
Maybe be abuse by bulimics
