Colonic polyps

Question 1

Colonic polyps

Answer 1

Masses protruding into gut lumen
Sawtooth appearance 
90% non neoplastic
Often rectosigmoid
Can be tubular or villous

Question 2

Adenomatous

Answer 2

Adenomatous are precancerous
Malignant risk increased with size, villous histology, epithelial dysplasia

Precursor to colorectal cancer (CRC)
The more villious the more polyps, the more likely malignant (villous=villainous)

Polyp symptoms: often asymptomatic, lower GI bleed, partial obstruction, secretory diarrhea.

Question 3

Hyperplastic

Answer 3

Most common non neoplastic poly in colon

>50% in rectosigmoid colon

Question 4

Juvenile

Answer 4

Mostly sporadic lesions in children <5 yrs
80% in rectum
If single, no malignant potential

Juevenile polyposis syndrome: multiple in GI
increased risk of adenocarcinoma

Question 5

Peutz-Jeghers

Answer 5

Single polyps are not malignant
Peutz-Jeghers: AD multiple nonmalignant hamartomas throughout GI, hyperpigmented mouth, lips, hand, genitalia

Associated with increased risk of CRC an other malignancies.