TYPHOID FEVER

Question 1

Typhoid fever ETIOLOGIC AGENT

Answer 1

Salmonella typhi

Question 2

Typhoid fever Source of infection

Answer 2

Feces and urine of infected persons

PS: Ulceration of peyer’s patches that causes emboli to the skin (rose spots)

Question 3

Typhoid fever Incubation period

Answer 3

1-3 wks

Question 4

Typhoid fever Mode of transmission

Answer 4

● Direct or indirect contact; feces/urine
● 5Fs
● Contaminated water

Question 5

Typhoid fever S/sx
S, H, R, U, L, S

Answer 5

● Step like or ladder like fever
● Headache
● Rose colored spots on the trunk , chest and abdomen
● Ulceration of peyer’s patches
● Loss if appetite
● Splenomegaly

Question 6

Typhoid fever Dx tests
W, C (WelCome)

Answer 6

● Widal Test/Typhidot; test for agglutination (the antigen-antibody response will clamp together)
● CBC; expect leukopenia

Question 7

Typhoid fever Nursing Management

Answer 7

● TSB to promote heat loss
● Oral care
● Report blood in the stools

Question 8

Typhoid fever DOC
C,C,A

Answer 8

● Chloramphenicol
● Cotrimoxazole
● Ampicillin

Question 9

Typhoid fever PATHOGENESIS

Answer 9

1. Ingestion of contaminated food/water
2. Attach to Peyer’s patches in terminal ileum
3. Incubation stage
4. Pass through lymphatics to reticuloendothelial system (Pass into circulation= abscesses and osteomyelitis)
5. From gallbladder secreted back into GI tract (Cholecystitis)
6. Necrosis and ulceration of Peyer’s patches
7. Intestinal perforation and bleeding