PTB Flashcards

1
Q

Highly infectious chronic dse. Caused by tubercle bacilli

A

Pulmonary TB

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2
Q

CAUSATIVE AGENTS

A
  1. Mycobacterium tuberculae
  2. M. Africanum
  3. M. Bovis
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3
Q

Classification

A

Bacterial

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4
Q

TB among children

A

Primary complex (not contagious)

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5
Q

2 types of TB

A
  1. Pulmonary TB- micro-bacterium within lungs
  2. Extrapulmonary TB- adjacent organs
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6
Q

Mode of transmission
D, A, D, I

A

DROPLET
AIRBORNE
DIRECT INVASION (rare)
INGESTION OF UNPASTEURIZED MILK OR DAIRY PRODUCTS

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7
Q

Extreme temp to destroy microorganisms in unpasteurized milk

A

63 deg celsius (30mins)/71.6-71.7 deg F (5-15secs)

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8
Q

Incubation period

A

2-8 wks (12 wks max)

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9
Q

Period of communicability

A
  • while bacillus is in the sputum
  • good compliance to regimen (not contagious 2-4 wks. After)
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10
Q

Terminologies
C, H, H

A
  1. Close contact
  2. High risk group
  3. High risk clinical group
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11
Q

Close contact

A

Enclosed space for 3 mos.

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12
Q

High risk group

A

Closed environment (prison cell, skin-to-skin contact)

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13
Q

High risk clinical group

A

AIDS/HIV/DM/RF (immunocompromised pt.)

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14
Q

6 Cardinal sign of PTB
C, NS, WL, A, H, LGF (CNS, WLAH, LGF)

A

Cough productive
Night sweats
Weight loss
Anorexia
Hemoptysis
Low grade fever in the afternoon

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15
Q

Dx test

A
  1. DSSM (Direct sputum smear microscopy)
  2. X-rays
  3. TST (Tuberculin Skin Test- primary complex)
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16
Q

DSSM
Conventional strategy (SPOT)

A

Instruct the patient to return the next day, early in the morning

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17
Q

DSSM
SPOT-SPOT

A

3 SPECIMENS
1st- right away/after chief complaint
2nd- after 1 hr
3rd- the next day, early in the morning

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18
Q

Sputum analysis

A

If 2 sputum are (+) = PTB
If 1 (-) and 1 (+) = Chest x-ray

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19
Q

Classification based on history of previously TB treatment
N, R, T, T, O, P (Nursing Reaching To TOP)

A

New pt.
Relapse pt.
Treatment after failure
Treatment after loss to follow up pt.
Other previously treated pt.
Pt. With unknown previous TB treatment history

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20
Q

New pt

A

Not yet diagnosed/ with TB before and taking anti-tubercular drug for 2 mos.

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21
Q

Relapse pt.

A

After receiving treatment for her TB, pt. Was diagnosed again with the illness

22
Q

Treatment after failure pt.

A

The TB treatment was unsuccessful

23
Q

Treatment after loss to follow-up pt.

A

Return after default/loss of contract or follow up for 2 mos.

24
Q

Other previously treated pt.

A

No known treatment/undocumented TB treatment

25
Q

Pt. With unknown previous TB treatment history

A

Does not fit in any category under classification of previous TB treatment

26
Q

DOTS

A

Directly Observed Treatment Short Course
- appointed person to monitor the daily intake (assigned health worker)

27
Q

Intensive phase

A

2 mons.

28
Q

Maintenance phase

A

4 mos.

29
Q

Recommended category of treatment regimen
4C’s?

A

C1, 2, 3, 4

30
Q

C1

A
  • new PTB, (+) smear, extensive parenchymal lesions (lungs), seriously ill, x-ray
    IP: 2 mos. HRZE (RIPE)
    MP: 4 mos. HR (RI)
31
Q

C2

A

Relapse, tx failure, return after default, and others
IP: 2 mos. HRZES (RIPES)
MP: 5 mos. HRE (RIE)

32
Q

C3

A

New PTB, with minimal lesions, not seriously ill
IP: 2 mos. HRZ (RIP)
MP: 4 mos. HR (RI)

33
Q

C4

A

Chronic PTB, (+) TB, (+) SPUTUM SMEAR AFTER SUPERVISED TX.
No meds

34
Q

Scone line drugs: Injectables
Aminoglycosides

A

Kanamycin
Amikacin
Capreomycin

35
Q

Second line drugs: Oral
Fluoroquinolone

A

Levofloxacin
Ciprofloxacin
Moxifloxacin

36
Q

JAUNDICE

A

RIPE

37
Q

Visual impairment

A

Ethambutol

38
Q

Tinnitus and hearing impairment

A

Streptomycin

39
Q

Oliguria and albuminiria

A

Strep and rifampicin

40
Q

Psychosis and convulsion

A

Isoniazid

41
Q

thrombocytopenia & anemia

A

Rifampicin

42
Q

DR- TB

A

DRUG RESISTANCE- ISONIAZID

43
Q

MDR- TB

A

MULTIPLE DRUG RESISTANCE- ISO & RIFAM

44
Q

XDR-TB

A

EXTENSIVELY DRUG RESISTANCE- ISO, RIFAM, FLUORO

45
Q

XXDR-TB

A

EXTREMELY DRUG RESISTACE- ISO, RIFAM, & FLUORO

46
Q

TDR- TB

A

TOTAL DRUG RESISTANCE- ISO, RIFAM, FLUORO

47
Q

RIFAM (SE)

A

RED ORAGE URINE, SWEAT, TEARS, SEMEN

48
Q

ISO (SE)

A

PERIPHERAL NEURITIS (PRICKILING OR TINGLING SENSATION)
VIT B6 FOR SE

49
Q

PYRAZINAMIDE (SE)

A

HYPERURICEMIA (INCREASED URIC ACID OR GOUT)
NEPHROTOXICITY/HEPATOTOXICITY (ALT & AST)

50
Q

ETHAMBUTOL (SE)

A

OPTIC NEURITIS/ BLURRING OF VISION

51
Q

STREP (SE)

A

8TH CRANIAL NERVE
VERTIGO & TINNITUS

52
Q

MANTOUX TEST (PURIFIED PROTEIN DERIVATIVE)

A

ROUTE OF ADMINISTRATION: ID

WHEAL FORMATION
(+) 10mm - exposure to normal people
(+) 5mm- exposure to immunocompromised people (HIV/AIDS)