Tumormarker, Ak.. Flashcards

1
Q

Bedeutung von AFP?

A
  • Tumore:
    • HCC
    • Embryonalzell-, Dottersack-CA
  • Pränatal-Dg:
    • erhöht bei Bauchwand-, Neuralrohrdefekten
    • vermindert bei Trisomie 21
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2
Q

Bedeutung von b-HCG:

A
  • Tumore:
    • Ovar: Chorion-CA
    • Hoden: Chorion-, Embryonalzell-CA, Seminom
  • SS-Test
  • Blasenmole
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3
Q

CA-125:

A
  • Ovarial-CA (80-100%)
  • Zervix-CA
  • andere gynäkolog. Tumore
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4
Q

CA 19-9:

A
  • Pankreas-CA
  • Magen-CA
  • CRC
  • Gallengangs-CA
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5
Q

Calcitonin:

A

medulläres SD-CA

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6
Q

CEA:

A

bei meisten Adeno-CA:

  • Bronchus-CA (inkl. SCLC)
  • Mamma-CA, Endometrium-CA
  • GIT-CA
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7
Q

Chromogranin-A:

A
  • NET
  • Phäochromozytom
  • medulläres SD-CA
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8
Q

NSE

A
  • SCLC
  • NET
  • Neuroblastom
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9
Q

PLAP (plazentare alkalische Phosphatase):

A

Seminom

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10
Q

Vimentin (IHC):

A
  • Sarkome
  • Mesotheliom
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11
Q

Desmin (IHC):

A

Rhabo- & Leimyosarkome

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12
Q

Bei welchen Tumoren v.a. paraneoplastische zerebelläre Ak:

A
  • Ovarial-, Mamma-, Uterus-CA
  • Bronchus-CA

Anti-Hu- und Anti-Yo-Ak

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