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Chemistry Module 4 > Tumor Markers Part 2 > Flashcards

Tumor Markers Part 2 Flashcards

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0
Q

This tumor marker can detect non-Hodgkin’s lymphoma, acute leukemia, and testicular cancer.

A

LD

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1
Q

this tumor marker is seen in primary or secondary liver cancer; greatest elevation seen in patients with prostate cancer with bone metastases

A

ALP

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2
Q

This tumor marker is found in neuronal tissue and detects neuroblastomas, carcinoid tumors, and pheochromocytoma.

A

Neuron-Specific Enolase (NSE)

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3
Q

This tumor marker is primarily used to screen, stage, and monior treatment and recurrence of prostate cancer.

A

Prostate specific antigen (PSA)

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4
Q

This tumor marker detects pituitary tumors or ectopic ACTH producing tumors

A

adrenocorticotrophic hormone (ACTH)

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5
Q

This tumor marker is used to detect familial medullary carcinoma of the thyroid (autosomal dominant)

A

calcitonin

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6
Q

This tumor marker is used to detect gastrinomas, which cause Zollinger-Ellison syndrome

A

Gastrin

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7
Q

This marker is elevated in trophoblastic diseases (associated with the uterine endometrial lining) and germ cell tumors; can go along with AFP to identify testicular tumors

A

Human Chorionic Gonadotropin

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8
Q

these two catecholamines are increased in pheochromocytomas (tumors in adrenal medulla)

A

epinephrine and norepinephrine

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9
Q

This catecholamine is increased in neuroblastomas

A

dopamine

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10
Q

This tumor marker arises from carcinoid tumors of the GI tract and pancreas

A

serotonin and 5-HIAA

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11
Q

In cancer patients, production of these antigens demonstrates that certain genes are reactivated during malignant cellular transformation.

A

oncofetal antigens

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12
Q

this is found in hepatocellular and germ cell (non-seminoma) carcinoma
LIVER CANCER

A

alpha fetoprotein

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13
Q

this marker is useful for colorectal carcinoma (70%) COLON CANCER

A

carcinoembryonic antigen (CEA)

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14
Q

This marker is elevated in 69% of cases of breast cancer; not used to diagnost but most useful in followup of treated breast cancer

A

CA 15-3

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15
Q

This marker is used for the detection of recurrent breast cancer in patients with stage II or stage III disease

A

CA 27.29

16
Q

This marker is usedful in detecting active breast cancer, but not early breast cancer

A

CA 549

17
Q

This is used as a marker for ovarian cancer, useful in differentiating benign from malignant disease in patients with palpable ovarian masses

A

CA 125

Chemistry Module 4 (15 decks)

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