Tumor Markers Flashcards

1
Q

Alkaline Phosphatase

A

Metastases to bone, liver, Paget’s

seminoma (placental ALP)

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2
Q

Alpha fetoprotein

A

hepatocellular carcinoma
yolk sack tumor
testicular cancer
mixed germ tell tumor (with b-hcg)

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3
Q

Beta-hCG

A

hydatidiform moles
choriocarcinoma
testicular cancer

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4
Q

CA-15-3/CA-27-29

A

Breast cancer

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5
Q

CA-19-9

A

Pancreatic adenocarcinoma

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6
Q

CA-125

A

ovarian cancer

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7
Q

Calcitonin

A

Medullary thyroid carcinoma

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8
Q

CEA

A

lots of cancers, but present in 70% of colorectal cancers

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9
Q

PSA

A

prostate cancer (questionable)

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10
Q

s-100

A

neural crest origin

  • melanoma
  • schannomas
  • Langerhan’s cell histocytosis
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11
Q

TRAP

A

Hairy cell leukemia (B cell)

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