Cytokines Flashcards
1
Q
IL-1
A
pyrogen
2
Q
IL-2
A
stimulates T cells
3
Q
IL-3
A
stimulates bone marrow
4
Q
IL-4
A
Stimulates IgE production
5
Q
IL-5
A
stimulates IgA production
6
Q
IL-6
A
causes fever and stimulates acute phase proteins
7
Q
IL-8
A
chemotactic factor for neutrophils
8
Q
IL-12
A
induces differentiation of T cells into Th1 cells.
9
Q
TNF-alpha
A
mediates septic shock
activates endothelium
causes leukocyte recruitment and vascular leak
10
Q
Secreted by macrophages
A
IL-1 IL-6 IL-8 IL-12 TNF-alpha
11
Q
Secreted by all T cells
A
IL-2
IL-3
12
Q
Secreted by Th1 cells
A
IFN-gamma
13
Q
Secreted by Th2 cells
A
IL-4
IL-5
IL-10
14
Q
IFN-gamma
A
Antiviral and antitumor
15
Q
IL-10
A
modulates inflammatory response
Inhibits activated T cells and Th1 cells
