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Pharmacology (personal) > treatments > Flashcards

treatments Flashcards

1
Q

candida albicans

A

Nystatin, clotrimazole

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2
Q

staphylococcus (resistant)

A

cloxacillin and vancomycin/linezolid

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3
Q

clostridium defficile

A

(pseudomembranous enterocolitis)
(because of broad spectrum antibiotics)
tx - metronidazole and vancomycin

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4
Q

proteus

A

cephalosporins, gentamicin

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5
Q

pseudomonas

A

piperacillin, carbenicillin, ceftazidime, cefaperazone, gentamicin

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6
Q

neomycin

A

damage intestinal mucosa

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7
Q

chloramphenicol

A

gray baby syndrome

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8
Q

sulfonamides

A

kernicterus (displaces bilirubin from protein binding site)

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9
Q

tetracyclines

A

discoloration and weakness of the teeth

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10
Q

macrolides, aminoglycosides work at pH

A

alkaline

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11
Q

syphilis

A

tetracyclines, penicillin

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12
Q

prostate

A

fq, trimethoprime

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13
Q

pregnancy safe

A

penicillin, cephalosporins, erythromycin

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14
Q

tetracyclines in pregnancy causes

A

acute yellow atrophy, pancreatitis, kidney damage - mother

teeth and bone deformation in child

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15
Q

hemolysis in g6pd patients

A

primaquine, nitrofurantoin, sulfonamides, chloramphenicol

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16
Q

cotrimoxazole

A

uti, prostatitis, respiratory, otitis media, bacterial diarrheas, pneumonia in neutropenic and AIDS, chancroid, typhoid,

used in agranulocytosis patients

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17
Q

pneumocystis jiroveci

A

one DS tablet 4-6 times a day for 2-3 weeks

one DS daily - prophylactic

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18
Q

chancroid

A

ceftriaxone, azithromycin, ciprofloxacin, cotrimoxazole

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19
Q

nalidixic acid

A

urinary,
(nitrofurantoin antagonise it’s effect)
diarrhea

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20
Q

ciprofloxacin

A

uti, gonorrhoea, bacterial gastroenteritis, wound infections (staph, gram negative bacteria), chanroid, typhoid, respiratory infection (not by pneumo/strepto), tuberculosis 2nd line (mdr), septicemia, meningitis, prophylactic, conjunctivitis

enzyme inhibitor

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21
Q

diabetic foot

A

clindmaycin/metronidazole + ciprofloxacin

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22
Q

inhalation anthrax biological warfare

A

cirpofloxacin

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23
Q

gram negative septicemia

A

ciprofloxacin + cephalosporins/aminoglycosides

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24
Q

norfloxacin

A

less potent- uti, bacterial diarrhea

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25
meningeal infections
fq pefloxacin (penetrability into csf) dose to reduced in case of liver disease
26
ofloxacin
chronic bronchitis, respiratory, ent infections, gonorrhoea
27
levooflxacin
pneumonia, chronic bronchitis, soft tissue infection, prostatitis
28
sparfloxacin
upper respiratory, ent, pneumonia, chronic bronchitis
29
moxifloxacin
respiratory infections
30
moxifloxacin contraindications
liver diseases, seizures, those proarrhythmogenic
31
gemifloxacin
pneumonia, chronic bronchitis
32
prulifloxacin
chronic bronchitis, uti
33
tularemia
streptomycin
34
tb
streptomycin
35
SABE
Streptomycin
36
plague
streptomycin, tetracyclines
37
topical use
gentamicin
38
second line drug in resistance tb
kanamycin
39
pseudomonas and proteus infections
tobramycin
40
bacterias producing aminoglycoside inactivating enzymes
amikacin (widest spectrum)
41
pseudomonas infection
tobramycin, sisomycin
42
bacterias producing aminoglycoside inactivating enzymes
netilmicin, amikacin
43
neomycin
not used systemically (oral/tropical application - less systemic toxicity)
44
topical wounds ulcers burns ear, eye infections
neomycin with polypeptide antibiotics
45
preparing bowel before surgery
neomycin with metronidazole
46
surgical prophylaxis
cefazolin, cephalexin, cephadroxil
47
hepatic coma
neomycin suppress intestinal flora that forms ammonia
48
hepatic coma
lactulose preffered
49
therapeutic concentration of erythromycin
in prostrate | also does not cross bbb, but cross serous membranes and placenta
50
erythromycin
stimulate motilin receptors - gastric emptying (prokinetic) - used in diabetic gaatroparesis
51
erythromycin
streptococcus infection, sabe, rheumatic fever pneumococcal infections h influenza diphtheria - 7 days treatment tetnus, syphilis, gonorrhea, leptospirosis WHOOPI COUGH CHANCROID
52
erythromycin (2nd choice)
legionella pneumonia, campylobacter enteritis, Chlamydiae trachomatous, penicillin resistant staph aureus
53
whooping cough
erythromycin corticosteroids beta stimulants
54
roxothromycin
(acid stable) Catarrhalis, G. vaginalis, legionella infections less enzyme inhibition
55
Chlamydiae trachomatous
azithromycin urithritis gential infections lymphogranuloma venereum trachoma in eyes
56
Chlamydiae pneumoniae
azithromycin
57
legionella pneumonia
azithromycin
58
calymm. granulomatous
Donovanosis azithromycin
59
CHANCROID
azithromycin | erythromycin
60
PPNG urethritis
azithromycin
61
MAC IN AIDS
clarithromycin | azithromycin
62
azithromycin
typhoid fever, toxoplasmosis
63
toxoplasmosis gondii / recurring abortion
``` SPIRAMYCIN 3 weeks course of 2-3 per day 3 MU 2Weeks gap repeated gap repeated gap repeated till delivery ```
64
pseudomembranous colitis
by defficile superinfection - metronidazole/vancomycin
65
prophylaxis endocarditis dental surgery
clindamycin
66
acne vulgaris
clindamycin
67
staph enterocolitis
vancomycin
68
enterococci endocarditis
vancomycin
69
empirical BACTERIAL MENINGITIS
vancomycin + ceftriaxone/cefotaxime
70
infection in cancer pts/ chemotherapy
vancomycin
71
vancomycin
pneumococcal infections diphtheriods infection surgical prophylaxis mrsa
72
vancomycin
pneumococcal infections diphtheriods infection surgical prophylaxis mrsa (teicoplanin can be given)
73
enterococci endocarditis
teicoplanin/vancomycin + gentamicin
74
SPECTINOMYCIN
resistant gonorrhoea | when beta lactams and macrolides allergic patients
75
nitrofurantoin
uncomplicated uti upper bc of e coli with no prostatitis

Pharmacology (personal) (21 decks)

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