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Pharmacology (personal) > treatments > Flashcards

treatments Flashcards

1
Q

candida albicans

A

Nystatin, clotrimazole

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2
Q

staphylococcus (resistant)

A

cloxacillin and vancomycin/linezolid

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3
Q

clostridium defficile

A

(pseudomembranous enterocolitis)
(because of broad spectrum antibiotics)
tx - metronidazole and vancomycin

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4
Q

proteus

A

cephalosporins, gentamicin

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5
Q

pseudomonas

A

piperacillin, carbenicillin, ceftazidime, cefaperazone, gentamicin

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6
Q

neomycin

A

damage intestinal mucosa

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7
Q

chloramphenicol

A

gray baby syndrome

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8
Q

sulfonamides

A

kernicterus (displaces bilirubin from protein binding site)

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9
Q

tetracyclines

A

discoloration and weakness of the teeth

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10
Q

macrolides, aminoglycosides work at pH

A

alkaline

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11
Q

syphilis

A

tetracyclines, penicillin

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12
Q

prostate

A

fq, trimethoprime

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13
Q

pregnancy safe

A

penicillin, cephalosporins, erythromycin

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14
Q

tetracyclines in pregnancy causes

A

acute yellow atrophy, pancreatitis, kidney damage - mother

teeth and bone deformation in child

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15
Q

hemolysis in g6pd patients

A

primaquine, nitrofurantoin, sulfonamides, chloramphenicol

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16
Q

cotrimoxazole

A

uti, prostatitis, respiratory, otitis media, bacterial diarrheas, pneumonia in neutropenic and AIDS, chancroid, typhoid,

used in agranulocytosis patients

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17
Q

pneumocystis jiroveci

A

one DS tablet 4-6 times a day for 2-3 weeks

one DS daily - prophylactic

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18
Q

chancroid

A

ceftriaxone, azithromycin, ciprofloxacin, cotrimoxazole

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19
Q

nalidixic acid

A

urinary,
(nitrofurantoin antagonise it’s effect)
diarrhea

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20
Q

ciprofloxacin

A

uti, gonorrhoea, bacterial gastroenteritis, wound infections (staph, gram negative bacteria), chanroid, typhoid, respiratory infection (not by pneumo/strepto), tuberculosis 2nd line (mdr), septicemia, meningitis, prophylactic, conjunctivitis

enzyme inhibitor

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21
Q

diabetic foot

A

clindmaycin/metronidazole + ciprofloxacin

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22
Q

inhalation anthrax biological warfare

A

cirpofloxacin

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23
Q

gram negative septicemia

A

ciprofloxacin + cephalosporins/aminoglycosides

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24
Q

norfloxacin

A

less potent- uti, bacterial diarrhea

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25
Q

meningeal infections

A

fq pefloxacin (penetrability into csf)

dose to reduced in case of liver disease

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26
Q

ofloxacin

A

chronic bronchitis, respiratory, ent infections, gonorrhoea

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27
Q

levooflxacin

A

pneumonia, chronic bronchitis, soft tissue infection, prostatitis

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28
Q

sparfloxacin

A

upper respiratory, ent, pneumonia, chronic bronchitis

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29
Q

moxifloxacin

A

respiratory infections

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30
Q

moxifloxacin contraindications

A

liver diseases, seizures, those proarrhythmogenic

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31
Q

gemifloxacin

A

pneumonia, chronic bronchitis

32
Q

prulifloxacin

A

chronic bronchitis, uti

33
Q

tularemia

A

streptomycin

34
Q

tb

A

streptomycin

35
Q

SABE

A

Streptomycin

36
Q

plague

A

streptomycin, tetracyclines

37
Q

topical use

A

gentamicin

38
Q

second line drug in resistance tb

A

kanamycin

39
Q

pseudomonas and proteus infections

A

tobramycin

40
Q

bacterias producing aminoglycoside inactivating enzymes

A

amikacin (widest spectrum)

41
Q

pseudomonas infection

A

tobramycin, sisomycin

42
Q

bacterias producing aminoglycoside inactivating enzymes

A

netilmicin, amikacin

43
Q

neomycin

A

not used systemically (oral/tropical application - less systemic toxicity)

44
Q

topical wounds ulcers burns ear, eye infections

A

neomycin with polypeptide antibiotics

45
Q

preparing bowel before surgery

A

neomycin with metronidazole

46
Q

surgical prophylaxis

A

cefazolin, cephalexin, cephadroxil

47
Q

hepatic coma

A

neomycin suppress intestinal flora that forms ammonia

48
Q

hepatic coma

A

lactulose preffered

49
Q

therapeutic concentration of erythromycin

A

in prostrate

also does not cross bbb, but cross serous membranes and placenta

50
Q

erythromycin

A

stimulate motilin receptors - gastric emptying (prokinetic) - used in diabetic gaatroparesis

51
Q

erythromycin

A

streptococcus infection, sabe, rheumatic fever
pneumococcal infections
h influenza
diphtheria - 7 days treatment
tetnus, syphilis, gonorrhea, leptospirosis
WHOOPI COUGH
CHANCROID

52
Q

erythromycin (2nd choice)

A

legionella pneumonia, campylobacter enteritis, Chlamydiae trachomatous, penicillin resistant staph aureus

53
Q

whooping cough

A

erythromycin
corticosteroids
beta stimulants

54
Q

roxothromycin

A

(acid stable)
Catarrhalis, G. vaginalis, legionella infections

less enzyme inhibition

55
Q

Chlamydiae trachomatous

A

azithromycin

urithritis
gential infections
lymphogranuloma venereum
trachoma in eyes

56
Q

Chlamydiae pneumoniae

A

azithromycin

57
Q

legionella pneumonia

A

azithromycin

58
Q

calymm. granulomatous

A

Donovanosis

azithromycin

59
Q

CHANCROID

A

azithromycin

erythromycin

60
Q

PPNG urethritis

A

azithromycin

61
Q

MAC IN AIDS

A

clarithromycin

azithromycin

62
Q

azithromycin

A

typhoid fever, toxoplasmosis

63
Q

toxoplasmosis gondii / recurring abortion

A 
SPIRAMYCIN
3 weeks course of 2-3 per day 3 MU 
2Weeks gap
repeated
gap 
repeated
gap
repeated till delivery
64
Q

pseudomembranous colitis

A

by defficile superinfection - metronidazole/vancomycin

65
Q

prophylaxis endocarditis dental surgery

A

clindamycin

66
Q

acne vulgaris

A

clindamycin

67
Q

staph enterocolitis

A

vancomycin

68
Q

enterococci endocarditis

A

vancomycin

69
Q

empirical BACTERIAL MENINGITIS

A

vancomycin + ceftriaxone/cefotaxime

70
Q

infection in cancer pts/ chemotherapy

A

vancomycin

71
Q

vancomycin

A

pneumococcal infections
diphtheriods infection
surgical prophylaxis mrsa

72
Q

vancomycin

A

pneumococcal infections
diphtheriods infection
surgical prophylaxis mrsa (teicoplanin can be given)

73
Q

enterococci endocarditis

A

teicoplanin/vancomycin + gentamicin

74
Q

SPECTINOMYCIN

A

resistant gonorrhoea

when beta lactams and macrolides allergic patients

75
Q

nitrofurantoin

A

uncomplicated uti upper bc of e coli with no prostatitis

Pharmacology (personal) (21 decks)

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