spectrum

Question 1

cotrimoxazole

Answer 1

enterobacteriaceae (typhi, serratia, Klebsiella, yersinia) pneumocystis jiroveci, staph and strepto, H influenza, gonococci and meningococci

Question 2

sufonamides

Answer 2

most gram positive and gram negative aerobes, Chlamydiae, actinomycetes, nocardia, Toxoplasma

Question 3

quinolones (flourination at 6 and piperazine at 7 th position)

Answer 3

gram negative mostly

newer fq also inhibit gram positive

Question 4

nalidixic acid

Answer 4

gram negative coliforms

not pseudomonas

Question 5

newer fq

Answer 5

gram negative, gram positive and anaerobes

Question 6

ciprofloxacin

Answer 6

gram negative aerobes (enterobacteriaceae, neisseria) MIC <0.1 MICROGRAM/ML
hemophilous
campylobacter
vibrio

Question 7

pseudomonas pneumonia in cystic fibrosis

Answer 7

ciprofloxacin

Question 8

resistant typhoid

Answer 8

cirpofloxacin

Question 9

ofloxacin

Answer 9

gram positive, anaerobes, (somewhat less gram negative)
m tb (resistant), leprae

Question 10

levooflxacin

Answer 10

streptococcus pneumoniae, gram positive and negative

moderate - anaerobes

Question 11

lamofloxacin

Answer 11

gram negative bacteria, Chlamydiae, and rest like ciprofloxacin

Question 12

sparfloxacin

Answer 12

gram positive, anaerobes, bacillus fragilis

Question 13

moxifloxacin

Answer 13

strept. pneumonia, gram positive, some anerobes, tb, beta lactam resistant

Question 14

gemifloxacin

Answer 14

aerobic gram positive, some mdr

Question 15

prulifloxacin

Answer 15

gram positive and negative

Question 16

gentamicin (and amikacin)

Answer 16

coli, Klebsiella, pneumoniae, enterobacter, influenza, proteus, serratia, pseudomonas aeruginosa, staph aureus, strept fecalis, listeria, yersinia, citrobacter, fransisella, brucella, campylobacter

Question 17

netilmicin

Answer 17

Klebsiella, enterobacter, staphylococcus

Question 18

neomycin

Answer 18

most gram negative bacillus, some gram positive cocci

Question 19

macrolides

Answer 19

gram positive, some gram negative

static at low concentrations
cidal at high

Question 20

erythromycin

Answer 20

positive, some negative
like PnG
(strept pyogenes, pneumonia
n gonnorhea
clostridium
diphtheriae
listeria)
unlike pnG
(catarha, mycoplasma, campylobacter, legionella, g. vaginalis)

Question 21

clarithromycin

Answer 21

(acid stable)

mycobacterium
mac in aids
anaerobes
pylori 1-2 weeks
mycoplasma pneumonia
moraxella
legionella
strept pyogenes
staph aureus 

cross resistance with erythromycin

Question 22

azithromycin

Answer 22

(azalide congener of erythromycin)

mac
PP staph aureus
influenza
respiratory pathogens

cross resistance with erythromycin

LARGE INTRACELLULAR DISTRIBUTION

Question 23

respiratory pathogens

Answer 23

mycoplasma, Chlamydiae pneumoniae, trachomatis, legionella, moraxella, campylobacter, ducreyi, calymm granulomatis, N. gonorrhea

Question 24

clindamycin

Answer 24

gram positive cocci (except mrsa)
clostridium perfringes
diphtheria
nocardia
toxoplasmosis
actinomycetes
plasmodia
anaerobic bacteria like
BACTERIA FRAGILIS

accumulation in macrophages and neutrophils

Question 25

bacteria fragilis

Answer 25

ceftizoxime clindamycin linezolid

Question 26

vancomycin

Answer 26

gram positive cocci mrsa difficile s. viridians

Question 27

teicoplanin

Answer 27

im mrsa enterococci vre

Question 28

linezolid

Answer 28

mrsa, vre, brsa, streptococcus, m tb, clostridium, corynebacterium, listeria, BACRERIA FRAGILIS

Question 29

spectinomycin

Answer 29

gonorrhoea

Question 30

quin/dapfopristine PRISTINAMYCIN

Answer 30

``` positive cocci marsa vrsa Chlamydiae neisseria legionella ```

Question 31

mupirocin

Answer 31

streptococcus, staph, gram positive

Question 32

fusidic acid

Answer 32

steroidal staphylococcus TROPICAL

Question 33

cycloserine

Answer 33

mac, gram positive e coli, Chlamydiae