Drugs Flashcards
use
Clopidogrel
ADP inhibitor (Antiplatelet)
Aspirin
NSAIDS
Heparin
Anticoagulant (inhibits Thrombin)
Ketotifin
Mast Cell stabilizer
Loratadine
2nd Gen Antihistaminic (H1)
Second generation antihistaminics
Fexofenadine, loratidine, desloratidine, cetirizine, levocitirizine, azelastine, mizolastine, ebastine, rupatadine
Cinnarizine
Antihistaminic H1
anticholinergic, antiserotonergic, vasodilatory, sedative
H2 antagonist
Cimetidine, ranitidine, famotidine, roxatidine
oral iron preparations
ferrous sulfate, ferrous gluconate, ferrous fumarate, colloidal ferric hydroxide, carbonyl iron, (ferrous succinate, iron choline citrate, iron calcium complex, ferrous ammonium citrate, ferrous aminoate, ferrous glycerophosphate, ferric hydroxy polymaltose)
fondaparinaux
factor Xa inhibition - anticoagulant
danaparoid
heparan sulfate
thrombin inhibitor (direct)
parenteral - lepirudin, bivalirudin, argatroban
oral- dabigatran etexilate
protamine sulfate
heparin antagonist
oral anticoagulants
warfarin, dicumarol, nicoumalone, ethyl biscoumacetate, phenindione
factor Xa inhibitor
rivaroxaban
enteric coated tablet
erythromycin (bc its base is acid labile)
erythromycin
given as acid stable esters
erythromycin
acid labile enteric coated tablet secreted in bile wide distribution half life 1.5 hr
erythromycin
stearate
estolate
ethyl succinate
less acid labile
macrolides
erythromycin, roxithromycin, clarithromycin, azithromycin
antagonism
when drug action sites are proximally located
clindamycin
potentiate NM blockers
lincomycin
excretion bile
five hours half life
side effects diarrhea and colitis
urinary ph acidic
nitrofurantoin
methenamine
tetracyclines
cloxacillin
