Drugs Flashcards

use

1
Q

Clopidogrel

A

ADP inhibitor (Antiplatelet)

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2
Q

Aspirin

A

NSAIDS

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3
Q

Heparin

A

Anticoagulant (inhibits Thrombin)

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4
Q

Ketotifin

A

Mast Cell stabilizer

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5
Q

Loratadine

A

2nd Gen Antihistaminic (H1)

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6
Q

Second generation antihistaminics

A

Fexofenadine, loratidine, desloratidine, cetirizine, levocitirizine, azelastine, mizolastine, ebastine, rupatadine

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7
Q

Cinnarizine

A

Antihistaminic H1

anticholinergic, antiserotonergic, vasodilatory, sedative

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8
Q

H2 antagonist

A

Cimetidine, ranitidine, famotidine, roxatidine

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9
Q

oral iron preparations

A

ferrous sulfate, ferrous gluconate, ferrous fumarate, colloidal ferric hydroxide, carbonyl iron, (ferrous succinate, iron choline citrate, iron calcium complex, ferrous ammonium citrate, ferrous aminoate, ferrous glycerophosphate, ferric hydroxy polymaltose)

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10
Q

fondaparinaux

A

factor Xa inhibition - anticoagulant

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11
Q

danaparoid

A

heparan sulfate

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12
Q

thrombin inhibitor (direct)

A

parenteral - lepirudin, bivalirudin, argatroban

oral- dabigatran etexilate

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13
Q

protamine sulfate

A

heparin antagonist

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14
Q

oral anticoagulants

A

warfarin, dicumarol, nicoumalone, ethyl biscoumacetate, phenindione

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15
Q

factor Xa inhibitor

A

rivaroxaban

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16
Q

enteric coated tablet

A

erythromycin (bc its base is acid labile)

17
Q

erythromycin

A

given as acid stable esters

18
Q

erythromycin

A
acid labile
enteric coated tablet
secreted in bile
wide distribution
half life 1.5 hr
19
Q

erythromycin

A

stearate
estolate
ethyl succinate

less acid labile

20
Q

macrolides

A

erythromycin, roxithromycin, clarithromycin, azithromycin

21
Q

antagonism

A

when drug action sites are proximally located

22
Q

clindamycin

A

potentiate NM blockers

23
Q

lincomycin

A

excretion bile
five hours half life
side effects diarrhea and colitis

24
Q

urinary ph acidic

A

nitrofurantoin
methenamine
tetracyclines
cloxacillin

25
Q

urinary ph alkaline

A

cotrimoxazole
aminoglycosides
cephalosporins
fq

26
Q

ph immaterial ( urine)

A

ampicillin

chloramphenicol

27
Q

terizidone

A

two molecules of cycloserine

less neurotoxicity

28
Q

tb static

A

e, cs

29
Q

tb cidal

A

km, ofx, z, eto, pto