Antimicrobials Flashcards

1
Q

sulfonamides

A

sulfadiazine, para amino salicylic acid, sulfones

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2
Q

sulfones

A

dapsone

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3
Q

diamino pyramidines

A

trimethoprim, pyrimethamine

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4
Q

Quinolones

A

Flouroquinolones

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5
Q

flouroquinolones

A

inhibits DNA gyrase

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6
Q

Quinolones

A

nalidixic acid, norfloxacin, ciprofloxacin, prulifloxacin

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7
Q

beta lactams

A

cell wall synthesis inhibitors

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8
Q

cell wall synthesis inhibitors

A

vancomycin, beta lactams, cycloserine, bacitracin

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9
Q

leakage from cell membrane

A

polyenes, polypeptides

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10
Q

polypeptides

A

polymyxin B, bacitracin, colistin, tyrothricin

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11
Q

polyenes

A

amphotericin B, hamycin, nystatin

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12
Q

inhibition of protein synthesis

A

chloramphenicol, clindamycin, linezolid, tetracyclines, erythromycin

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13
Q

misreading of mRNA

A

aminoglycosides

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14
Q

antibacterial

A

penicillin, erythro, fq, aminoglycosides

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15
Q

antifungal

A

griseoful, amphotericin B, ketoconazole

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16
Q

macrolides

A

erythromycin, clarithromycin, azithromycin

17
Q

high therapeutic index

A

penicillin, cephalosporins, erythromycin

18
Q

aminoglycosides

A

ototoxicity, and kidney toxicity

19
Q

tetracyclines

A

liver and kidney damage, antianabolic

20
Q

chloramphenicol

A

bone marrow depression

21
Q

polymyxin B

A

neurological and renal toxicity

22
Q

vancomycin

A

hearing loss, kidney toxicity

23
Q

amphotericin b

A

kidney, bone neurological toxicity

24
Q

broad spectrum

A

tetracyclines, ampicillin, new cephalosporins, chloramphenicol

25
Q

superinfection diarrhea

A

tetracyclines, ampicillin, amoxicillin (because of less absorption)

26
Q

intestinal flora

A

B12, folic acid synthesis, vit K