Travel Infections Flashcards
What microorganisms can cause malaria?
Plasmodium falciparum
Plasmodium vivax
Plasmodium ovale
What is the vector for malaria?
Female anopheles mosquito
What are the symptoms of malaria?
Headache
Fever
Muscle ache
Splenomegaly
What is seen on a blood film in malaria?
Parasites in RBCs
How is malaria diagnosed?
3x blood film
How is malaria caused by plasmodium falciparum managed?
Artesunate
Quinine + doxycycline
How is malaria caused by plasmodium vivax/ovale managed?
Chloroquine
How is malaria prevented?
Bite prevention
Prophylaxis
What organisms cause enteric fever?
Salmonella typhi
Salmonella paratyphi
What is the transmission of typhoid?
Faecal-oral
What type of organism is salmonella typhi?
Enterobacteriaceae
Aerobic gram negative bacillus
What is the virulence of salmonella typhi?
Survives gastric acid
Fimbriae adhere to epithelium over ileal lymphoid tissue -> RE system
Reside within macrophages
What are the symptoms of enteric fever?
Fever
Headache
Abdominal discomfort
Relative bradycardia
What are investigation findings in enteric fever?
Moderate anaemia
Lymphopenia
Raised LFTs
How is enteric fever managed?
IV ceftriaxone or azithromycin
