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SL12001 Biochemistry > Transport of lipids > Flashcards

Transport of lipids Flashcards

1
Q

What is used to transport lipids?

A

Lipoprotein complexes

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2
Q

What are lipids transported via?

A

The bloodstream

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3
Q

How are lipoprotein complexes classified?

A

Density

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4
Q

What is an issue with classifying lipoprotein complexes by density?

A

There is overlap in composition from one tyre to the next

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5
Q

What are the four classifications of lipoprotein complex?

A

Chylomicrons, VLDL, LDL, HDL

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6
Q

VLDL stands for?

A

Very low density lipoproteins

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7
Q

LDL stands for?

A

Low density lipoproteins

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8
Q

HDL stands for?

A

High density lipoproteins

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9
Q

What are all classes of lipoproteins made up of?

A

Protein, phospholipid, free cholesterol, cholesteryl esters and triacylglycerols

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10
Q

What are the lipid droplets surrounded by in lipoprotein complexes?

A

Proteins and phospholipids

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11
Q

What do the proteins and phospholipids surrounding lipid droplets in lipoprotein complexes do?

A

Make them soluble in water

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12
Q

How are free fatty acids transported in the blood?

A

Bound to serum albumin, causing them to be solubilised

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13
Q

Order of lipoprotein complex that lipids cycle through when moving through the capillaries?

A

Chylomicron–> VLDL–>LDL–>HDL

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14
Q

What happens to a lipid before it progresses to the next lipoprotein complex?

A

Within the capillaries a lipoprotein lipase interacts with the lipoprotein complex, causing some of the lipids to be released and pass into the surrounding tissue

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15
Q

What happens to the lipids that dont get absorbed by the tissue surrounding the capillary?

A

The remnants from the lipoprotein complex they were in end up in the liver, and are modified to form the next lipoprotein complex

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16
Q

Where is lipoprotein lipase present?

A

Capillary surfaces of the tissues that absorb lipids from the blood

17
Q

Which tissues absorb lipids from the blood

A

mammary, muscle, adipose

18
Q

What activates lipoprotein lipase?

A

Apo-CII

19
Q

What is Apo-CII a component of?

A

Chylomicrons

20
Q

What can lipoprotein lipase break triacylglycerols down to?

A

FAs and monoacylglycerol

21
Q

What substances can diffuse and out of chylomicrons?

A

FAs and monoacylglycerol

22
Q

What happens to FAs once inside cells?

A

They are metabolised to give energy

23
Q
A

SL12001 Biochemistry (14 decks)

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