Mitochondrial electron transport system Flashcards
Travel of electrons through the inner mitochondrial membrane?
Enter at complex I, flow to CoQ, complex III and then complex IV
How many H+ are concomitantly translocated?
10
How many H+ are translocated via compelx I?
4
How many H+ are translocated by complex II?
4
How many H+ are translocated by complex III?
2
Where does FADH2 enter the ETC?
Complex II
What does FADH2 not do regarding the proton gradient?
Contribute to it
What is complex I called?
NADH-Ubiquinone Oxidoreductase
Where do the e- that enter complex I come from?
NADH
How do e- move through complex I?
They move through inorganic cofactors
How do the inorganic cofactors in CI remain in place?
They are covalently bound to the protein
What is flavin mononucleotide (FMN) used for in CI?
It accepts 2 e- from NADH
What does FMN accept (other than e-) and what does it form?
2 H+, forming FMNH2
What is the intermediate formed between FMN and FMNH2?
Semiquinone intermediate
Where do e- go after forming FMNH2?
Through Fe-S clusters