Trabecular Meshwork and Aqueous Outflow

Question 1

what is the anterior chamber depth? what is the horizontal diameter and vertical diameter?

Answer 1

3.6mm
11mm
vertical diameter is larger than the horiz by 100 micrometers

Question 2

what is the anterior chamber filled with? to support what? how much can it hold?

Answer 2

aqueous humor to suppor avascular area *lens,cornea, trab meshwork.
can hold 200 microliters

Question 3

where is the post chamber located? how much aqueous humor can it hold?

Answer 3

behind the iris and in front of the lens and can hold 50 micrometers

Question 4

where is the anterior chamber located?

Answer 4

behind the cornea and in front of the lens and iris

Question 5

the path of aqueous humor

1. secreted by _____
2. flows through the _____
3. flows through the ______
4. enters ____ on surface of the eye

Answer 5

1. ciliary body
2. pupil
3. outflow pathway
4. veins on surface of eye

Question 6

every minute, how many microliters of aqueous humor are produced by the ciliary body

Answer 6

2.5 microliters

Question 7

where is the trabecular meshwork

Answer 7

triangle that connects anteriorly to cornea and post to scleral spur

Question 8

where does desceme’s membrane of corneal epithelium end and trabecular meshwork bein?

Answer 8

schwalbe’s line

Question 9

wehre does trab meshwork insert

Answer 9

scerla spur-post area

Question 10

what causes the trab meshwork to open and help the aqueous drain

Answer 10

one of the layers of the ciliary muscle is the longitudinal bundle. when it contracts it pulls the scleral spur posteriorly

Question 11

what 2 parts are the trabeuclar meshwork divided into

Answer 11

uveal meshwork and corneosclera meshwork

Question 12

which meshwork is close to the iris (AC side) and which is closer to the outside of the eye

Answer 12

uveal

corneoscleral

Question 13

what is the pathway of the aqueous

Answer 13

uveal meshwork, corneoscleral meshwork, juxtacanalicular meshwork (JCT), schlemm’s canal, collector channels, deep scleral plexus, intrascleral plexus, episclearal veins

Question 14

which region is the non-filtering region TM? what amount of pigment is here? why?

Answer 14

anterior region (not against SC) 
LESS pigemnt bc LESS flow here. more towards cornea

Question 15

which region is the filtering region of TM? what amount of pigment? why?

Answer 15

post region (most flow go through this)
MORE pigment bc MORE flow here.
-phagocytic capabilities here

Question 16

Schwalbe’s line is the peripheral terminus of which corneal layer?

Answer 16

descemet’s

Question 17

the scleral spur serves as point of attachment for the:

Answer 17

longitudinal bundle of the ciliary muscle

Question 18

in a gonioscopic view of the ant chamber angle which is positioned most inferiorly?

Answer 18

ciliary body band

Question 19

gonioscopy is a lens used to see the angle and you will see 5 lines. from 1st to last what are tehy

Answer 19

schwalbe’s line (dark)
white and dark tabec meshwork
white scleral spur
ciliary body band

Question 20

which of the portions of the trab meshwork is most of the normal aqueous outflow resistance felt to reside?

Answer 20

JCT-only here the space is small enough to generate significant resistnace to maintain normal IOP

Question 21

which region of the trab meshwork is closest to the ant chamber?

Answer 21

uveal-closer to int of the eye

Question 22

which region is more toward the surface of the eye

Answer 22

schlemm’s canal

Question 23

which structures are observed along the inner wall endothelium of schlemm’s canal

Answer 23

giant vacuoles

Question 24

aqueous humor leaving the canal of schlemm that does NOT enter an aqueous vein would first enter what?

Answer 24

collector channel

Question 25

the approx %age of aq humor outflow that passes through the uveoscleral and trab outflow is?

Answer 25

20 and 80% respectively