Cartilage Flashcards
what type of tissue is cartilage ? what do its properties and function depend on ?
connective tissue. cells live in their own matrix. the properties and function of tissue depend on molec on the extracell matrix
cartilage is the only _____ connective tissue
avascular. need tissue w/ blood supply next to it and nutrients must diffuse through matrix
what are mature cells of cartilage called
chondocytes -often contain a lipid droplet
what are cartilages matrix components
what kind of matrix is it
collagen and proteoglycan (PGs)
avascular and non mineralized (bone is mineralizsed)
cartilage provides semi-rigid support in the….
trachea, ear, respiratory tree, joints
chondrocytes contain….
lipids, glycogen, well devleoped RER (for continuous secretion), golgi.
they are highly synthetic
chondrocytes are surrounded by…..
they have limited…
and have significant….
perichondrium. (undifferentiated cells, not in articular cartliage or fibrocartiblage, nearest blood vessels)
- limited mitosis. wounded=not easy to repari
- significant nutrient requirements (synthesize lots of matrix, prtoeglycans bc highly active)
link proteins bind what to waht
PGs to hyalouronic acid
collagen binds to waht
side chains of PGs -acts as spacers in between collagen type 2
what are the 3 types of cartialge
elastic, hyaline, fibrocartilage
what are chondroblasts
immature cells on their way to become mature chondrocytes
what are fibroblasts
most immature cells
the perichondrium contain what
chondroblasts and fibroblasts
-chondroblasts are more mature than fibroblasts
in the extracellular matrix: hyaline is mainly what type of collagen
type 2-stains pink
what are some locations of hyaline cartilage
fetus skeleton template, articular surfaces of joints (adult), tracheal rings, bronchi, larynx, nose, costal (rib) cartilage
what is an isogenous group of chondrocytes
cells that are undergoing active mitosis
-synthesis matrix to push away from each other and make tissue bigger
the territorial matrix is the…
the interterritorial matrix is the…
immature matrix
more mature
the outermost layers of perichondrium have…
vasculature
2 types of cartilage growth. what are they
appositional-main type
interstitial-during early growth
chodrogenic cells in periochondrium to chondroblassts, lay down matrix at surface. waht kind of growth?
appositional
there is
pre-existing chondrocytes divide, add matri w/in cartilage center. what kind of groth
interstitial (center)
hyaline cartilage:
- ________ surrounded by a perichondirum except in articualr cartilage
- has an outer _____ layer, an inner _____ layer and blood vessels
- type ___ collagen
- temporary skeleton of the…
- proteoglycans
- avascular
- fibrous
- chondrogenic
- type 2
- embryo, articular cartilage (no perichondrium here) and much of the respiratory tract (nose, larynx, trachea, and bronchi) and costal cartilage too T__T
lacuna are…
cells no longer in their spaces
elastic cartilage:
- matrix is like _____ but here it has elastic fibers and sheets along w/ collagen
- elastic, resilience, and ______
- matrix is not ______
- located in the …..
- hyaline
- pliability
- calcified
- external ear, auditory canal, tube, epiglottis, larynx
