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PH 172 > Toxoplasma + Cryptosporidium > Flashcards

Toxoplasma + Cryptosporidium Flashcards

1
Q

phylum of Cryptosporidium

A

Apicomplexa

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2
Q 
false about Cryptosporidium
A. only affects humans
B. opportunistic
C. causes water-borne diarrhea
D. can be seen through acid fast stain
A

A

zoonotic siya

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3
Q

Each Cryptosporidium oocyst contains how many naked sporozoites?

A

4

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4
Q

enumerate processes of Cryptosporidium that occur in the small intestine

A

merogony/schizogony
gametogony
sporogony

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5
Q

[Cryptosporidium]

Where does merogony take place, and how many merozoites does it yield?

A

microvilli

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6
Q

[Cryptosporidium]

Water and food are contaminated with ___ oocysts

A

thick-walled

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7
Q

[Cryptosporidium]

Describe asexual cycle of reproduction.

A

merozoites invade other enterocytes to produce more merozoites

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8
Q

[Cryptosporidium]

first step of sexual cycle of reproduction

A

gametogony to form microgamont & macrogamont

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9
Q

[Cryptosporidium]
Which is true?
A. A microgamont fertilizes a macrogamont.
B. A microgamete from a macrogamont fertilizes a microgamont.
C. A microgamete from a microgamont fertilizes a macrogamont.
D. Microgamonts and macrogamonts are not formed.

A

C

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10
Q 
[Cryptosporidium]
Which type of oocyst causes autoinfection?
A. thin-walled oocyst
B. thick-walled oocyst
C. both
D. no auto-infection occurs
A

A

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11
Q 
[Cryptosporidium]
not an established mode of transmission
A. hand to mouth
B. handling animals
C. human and animal feces contam
D. injection of needles
A

D

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12
Q 
[Cryptosporidium]
affected in pathogenesis
A. cGMP
B. cAMP
C. CFTR
D. All of the above
A

B

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13
Q 
[Cryptosporidium]
stool sample of patient with this parasite is often like
A. dysentery
B. cholera
C. EHEC
D. none of the above
A

B

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14
Q 
[Cryptosporidium]
main site of pathogenesis
A. duodenum
B. ileum
C. jejunum
D. all  of the above
A

A

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15
Q 
[Cryptosporidium]
other sites of pathogenesis include all except
A. biliary tree
B. brain
C. gall bladder
D. respiratory tract
A

B

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16
Q

Enumerate acid fast staining methods for Cryptosporidiun

A

Kinyoun
modified Ziehl-Neelsen
Auramine

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17
Q

specimen viewed in immunofluorescence test for Cryptosporidium

A

oocyst

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18
Q

current drug of choice for Cryptosporidium

A

nitazoxanide`

19
Q

Which is false?
A. Wash hands before handling food/after defecation to prevent transmission of Cryptosporidium.
B. Fluid replacement (via oral or IV) may be used for treatment of Cryptosporidium.
C. both are true

A

C

20
Q

[Toxoplasma]

only part of tachyzoite stage that is seen in light microscope

A

nucleus

21
Q

[Toxoplasma]

shape of tachyzoite stage

A

piriform

22
Q

[Toxoplasma]

wall of mature pseudocyst: composition

A

combination of host and parasitic components

23
Q

[Toxoplasma]

tissue cysts are often found in the ___ of the host

A

muscles

24
Q

[Toxoplasma]

T/F. Oocysts shed @ cat feces are infective.

A

F. Oocysts sporulate @ envt –> infective

25
Q

[Toxoplasma]

Upon entry, oocyte undergoes ___ and enters enterocytes/mucosal cells

A

schizogony

26
Q

[Toxoplasma]

After schizogony & entering mucosal cells, sporozoite multiplies into many merozoites. This process is called __

A

endodyogeny

27
Q

[Toxoplasma]

Merozoites –> ___ @ definitive host

A

tachyzoites

28
Q 
[Toxoplasma]
Humans are infected by eating undercooked meat of animals that have \_\_ stages.
A. sporozoite
B. merozoite
C. bradyzoite
A

C

29
Q 
[Toxoplasma]
What does the parasite form inside human host?
A. tachyzoite
B. bradyzoite
C. tissue cyst
D. all of the above
A

C

30
Q

[Toxoplasma]
t/f
humans are definitive host

A

f

Family Felidae (Cats plus relatives) ang definitive host
humans: intermediate host
31
Q

[Toxoplasma]

enumerate most affected cells by this parasite

A

macrophage

dendritic cell

32
Q

[Toxoplasma]

type of exanthem seen in Toxoplasma patients

A

typhus like (Rickettsia-like)

33
Q

[Toxoplasma]

Why is chorioretinitis possible?

A

blindness by presence of cyst @ eye

34
Q

[Toxoplasma]

What is Sabin Syndrome?

A

internal hydrocephalus, chorioretinitis, convulsions, cerebral calcification

35
Q

[Toxoplasma]

What is Sabin-Feldman dye test?

A

method involving incubation of live trophozoites, and if Abs are present, cell membrane is destroyed & dye will get inside cell

36
Q

[Toxoplasma]

dye @ Sabin-Feldman test

A

methylene blue

37
Q

[Toxoplasma]

diag method @ 1st term of pregnancy

A

IgM ELISA

38
Q

[Toxoplasma]

type of lesions seen @ brain MRI of patient with Toxoplasma

A

ring typical lesions

39
Q

[Toxoplasma]

skin test for this parasite

A

Frenkel side test

40
Q

[Toxoplasma]

Drugs vs Toxoplasma can lyse tissue cysts of the parasite.T/F

A

F

Drugs: for control only

41
Q

[Toxoplasma]

two animals that have higher prevalence of positive titers for Toxoplasma antibodies

A

pigs and rats

42
Q

[Toxoplasma]

what devt stage can be seen @ bone marrow samples

A

tachyzoites

43
Q

[Toxoplasma]

T/F tissue cysts have bradyzoites

A

T

PH 172 (25 decks)

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