Toxicology & Pharmacology (3%)

Question 1

Which of the following drug(s) is contraindicated for us with tizanidine?
•	Ciprofloxacin
•	Diltiazem
•	Erythromycin
•	Ketoconazole

Answer 1

• Ciprofloxacin

Question 2

Which of the following drugs works through reversible binding at the aromatase enzyme?
•	Bicalutamide
•	Toremifene
•	Leuprorelin
•	Anastrozole

Answer 2

• Anastrozole

Question 3

Which of the following is a correct list of how exposure to toxins can occur?
• inhaling, injecting, absorbing, ingesting
• injecting, inhaling, excreting, ingesting
• inhaling, injecting, excreting, absorbing
• absorbing, inhaling, excreting, ingesting

Answer 3

• inhaling, injecting, absorbing, ingesting

Question 4

Which of the following is used as an antidote for heparin poisoning?
•	Protamine sulfate
•	Methylene blue
•	Nalmefene
•	Calcium gluconate

Answer 4

• Protamine sulfate

Question 5

Hyperthermia in a patient of poisoning is a pointer to all EXCEPT:
•	Selective serotonin reuptake inhibitor
•	Ecstasy
•	Salicylates
•	Chlorpromazine

Answer 5

• Chlorpromazine

Question 6

What is the most common side effect experience by patients taking verapamil?
•	Constipation
•	Headache
•	Diarrhea
•	Hypertension

Answer 6

• Constipation

Question 7

A person was brought by police from the railway platform. He is talking irrelevant. He is having dry mouth with hot skin, dilated pupils, staggering gait and slurred speech. The most probable diagnosis is?
•	Alcohol intoxication
•	Carbamates poisoning
•	Datura poisoning
•	Organophosphorus poisoning

Answer 7

• Datura poisoning

Question 8

A 12-year-old boy had an alleged history of snake bite and presented to the hospital with inability to open eyes well and difficulty in breathing. He is very anxious and is having tachycardia and tachypnea. On examination bite mark cannot be visualized and there is no swelling of the limb. He has bilateral ptosis. His 20 min whole blood clotting test is good quality. What is the next course of action?
• Give ASV and keep the patient in observation
• “Reassure the patient and send him home with
anxiolytic”
• “Don’t give anti-snake venom (ASV), but
observe the patient”
• “Give ASV, and give neostigmine and observe
the patient”

Answer 8

• “Give ASV, and give neostigmine and observe

the patient”

Question 9

Which antibacterial drug is known to discolour urine a brown-ish hue?
•	Clofazimine
•	Benzylpenicillin
•	Nitrofurantoin
•	Doxycycline

Answer 9

• Nitrofurantoin