Toxicity Treatments Flashcards
Acetaminophen
N-Acetylcysteine Replenish Glutathione (GSG)
AChE Inhibitors
Organophosphates
Atropine: Central and Peripheral
Pralidoxime: Peripheral
Antimuscarinic/Anticholinergic Agents
Physostigmine
Control Hyperthermia
Arsenic
Dimercaprol
Succimer
Benzodiazepenes
Flumazenil
Beta-Blockers
Atropine
Glucagon
Carbon Monoxide
100% O2
Hyperbaric O2
Copper
Penicillamine
Trientine
(Think Wilson’s)
Cyanide
Nitrite + Thiosulfate
Hydroxycobalamin
Digitalis (Digoxin)
Anti-dig Fab fragments
Heaparin
Protamine Sulfate
Iron
Deferoxamine
Derasirox
Deferiprone
Lead
EDTA
Dimercaprol
Succimer
Penicillamine
Mercury
Dimercaprol
Succimer
Methanol or Ethylene Glycol
- Fomepizole
- Ethanol
- Dialysis
Methemoglobin
Methylene blue
Vitamin C
Opioids
Naloxone
Salicylates
NaHCO3 (Alkalinize urine)
Dialysis
TCA’s
NaHCO3
Warfarin
Vitamin K (Delayed) FFP (Immediate)
Neuroleptic Malignant Syndrome
Dantrolene
Serotonin Syndrome
Cyproheptadine
Tetrodotoxin MOA
Pufferfish
Binds fast voltage-gated Na+ channels in cardiac/nerve tissue - preventing depolarization
TX: Supportive
Ciguatoxin
Reef fish - Barracuda, Snapper, Moray eel
Opens Na+ channels causing depolarization
TX: Supportive
Spoiled dark-meat fish - Tuna, Mahi mani, Mackerel, Bonito
Scombroid poisoning
Bacterial Histidine decarboxylase converts Histidine to HISTAMINE
Looks like Anaphylaxis
Frequently misdiagnosed as fish allergy
TX: Antihistamines, Albuterol and Epinephrine if needed
